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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 12 Documents
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Search results for , issue "Volume 10 Issue 01: (2018) Jan. 2018" : 12 Documents clear
Analytical Method Development for Simultaneous Estimation of Cobicistat and Darunavir by RP-HPLC Method A. Sindhuja
Journal of Global Pharma Technology Volume 10 Issue 01: (2018) Jan. 2018
Publisher : Journal of Global Pharma Technology

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Abstract

A new method was established for simultaneous estimation of Cobicistat and Darunavir by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Cobicistat and Darunavir by using Xterra C18 5µm (4.6*250mm) column, flow rate was 1ml/min, mobile phase ratio was Phosphate buffer (0.05M) pH 4.6: ACN   (30:70%v/v)   (pH was adjusted with orthophosphoric acid), detection wave length was 255nm. Five trails have been done with various composition of mobile phase. Among them the mobile phase composition Acetonitrile and phosphate buffer in the ratio of 70:30 (trail no 5), using C18 column as stationary phase and detection at 255nm has produced a well resoluted peak. The no of theoretical plates was 5105, 3788 with a tailing factor of 1.3, 1.4. The peak retention time was 2.399, 3.907 with a peak area of 946124, 11541. The results shown that developed method is rapid, specific for the simultaneous estimation of cobicistat and darunavir in combined dosage form.Keywords: Cobicistat,Darunavir, RP-HPLC, Phosphate buffer, ACN
Evaluation of In-Vitro Anticancer Activity of Hibiscus Rosa Sinensis against HeLa cell Line P. Sampath Kumar
Journal of Global Pharma Technology Volume 10 Issue 01: (2018) Jan. 2018
Publisher : Journal of Global Pharma Technology

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Abstract

            The antifungal activity of Hibiscus rosa sinensis was evaluated against the following pathogenic fungi such as Candida albicans, Aspergillus niger, Trichoderma viride and  Rhizopus microsporus. The acetone extract of Hibiscus rosa sinensis flower showed little antifungal activity.  The acetone extract of Hibiscus rosa sinensis flower showed higher activity against HeLa cell line using MTT assay. The results obtained from the study revealed that Hibiscus rosa sinensis flower  Possess anticancer  activity against HeLa cell line using MTT assay.  

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