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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 69 Documents
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Search results for , issue "Volume 10 Issue 10: 2018" : 69 Documents clear
The Effect of Muscular Endurance Exercises According to Superset Theory in some Physiological Abilities and Completion of Running 800 Meters Advanced Suhad Qasem Al-Moussawi
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
Publisher : Journal of Global Pharma Technology

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Abstract

This study aimed to identify the effect of muscular endurance in the development of some physiological abilities to achieve an 800-meter run. The researchers hypothesized that there was a positive effect of the Super Set muscular endurance exercises in advanced race runners. The researchers used the experimental approach to suitability and the nature of the research. The study sample consisted of (10) players divided equally into experimental and control groups. The experimental group used muscle training exercises in Superset to develop physiological variables such as anaerobic and aerobic abilities and the concentration of lactic acid in blood. The control group In addition to the physiological variables such as the measurement of the levels of lactic acid in the blood (before and after) the brown effort, the experiment lasted (10) weeks and (3) units The results of the study showed that there were significant differences in some variables, such as the arithmetic mean, the standard deviation, the torsion coefficient, and the t-test of the interrelated samples. Physiology and the concentration of lactic acid in blood between the experimental and control groups. The results of the study showed the existence of random differences between the two groups in the post-test of the concentration of lactic acid before the effort.Keywords: Athletics, Running 800 meters, Superset exercises, Anaerobic and aerobic abilities and lactic acid concentration.
Antibacterial Activity of Origanumvulgare Leaves against Different Types of Bacteria Isolated from Urinary Tract Infection Patients in Baghdad/Iraq Hayfaa M. Fahad
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
Publisher : Journal of Global Pharma Technology

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Abstract

In the gift study, antibacterial drug potency of Origanumvulgare was studied on four sorts of morbific microorganism isolated from urinary tract infection patient samples, Staphylcoccus aureus, E. coli, Klebsiella pneumonia, and Sallmonellatyphi by agar well diffusion assay. The repressive effects of this leaves extract were compared with control distilled water. The inhibition result of Origanumvulgare in numerous concentration against microorganism growth were studied, the results showed that there's an excellent inhibition growth on all studied microorganism isolates except Klebsiella pneumonia. This study conclude that the data ensure the antibacterial drug potential and highlight the promising role of oregano as new lead structure within the explore for novel antibacterial drug agents. Therefore, any experiment involving a bigger sample size and extract a concentration is deserve analysis.Keywords: antibacterial drug, Vulgare.
Effects of Purified Bauhinia Variegate Leaves and Methanolic Extract on Diabetic Type-2 Alloxan-Induced in Male Albino Rats Jameelah Kadhim Taher
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The anti-diabetic effects of purified Bauhinia variegate leaves and methanolic extract were Compared with standard drug Insulin. In vivo studyreveals that animal treated with methanolic extract of Bauhinia variegate show reduction in blood glucose sigificantly, body weight, triglycerides, HDL, cholesterol in Alloxan induced diabetic rats. In Bauhinia variegate treated group, there are no significant increase in urea and creatinine level when compared to the control group which reveals the protective nature of the plant source. It concludes that In vivo antidiabetic activity of whole plant extracts of Bauhinia variegate on normal and Alloxan induced diabetic rats was evaluated and concluded that it possesses anti-diabetic activity. From the above results, it is conducted that purified leaves and methanolic extract of Bauhinia variegate whole plant possess significant hypoglycemic and hypolipidemic effects in alloxan induced diabetic rats.Keywords: Bauhinia variegates, Hypoglycemic, Hypolipidemic, Methanilic extract.
The Effect of Enrichment Activities on Positive Thinking and on the Skill of the High-dribble and the Scoring of Stability Amina Abbas Hassan
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

Through the experience of the researcher as a teacher working to develop the thinking of the student and give students freedom to think as well as to encourage them to participate positively in the classroom and learn the basic skills in an interesting and enjoyable so used the activities of enrichment and its connection to the process of positive thinking, and the utility of enrichment activities to transfer students from the status of the recipient Negative to the state of positive interaction during the course of the study and because of the recent enrichment activities and use in other materials such as mathematics, chemistry and Arabic use within the classroom, and the introduction of these activities in the enrichment curriculum. One of the contemporary trends in the development of the curriculum of sports in different stages of education, in order to achieve the principle of sport for all and so the researcher remained only to achieve the objectives of this study, which came as follows - to know the degree of positive thinking among fifth-grade students prepare - the number of educational units enrichment activities to learn to target of stability, and the high level of basketball in the fifth grade preparatory students. The research community was determined by the students of Al-Adhamiya for the fifth grade of Literary Literacy, which were 90 students divided into three groups (A + B + C). The research community was determined by the intentional method. The sample was randomly selected in the drawing method, and the number of (60) students distributed equally to the two divisions. Experimental Division A and Division C were withdrawn and pretest tests were conducted with selected skills and then the proposed curriculum was implemented. With 9 weeks. The number of educational units per week reached two educational units, (18) educational units. Different exercises were adopted, different from basketball activities and skills in warm-up and aim to avoid boredom and introduce the element of suspense and fun in the hearts of students. After completion of the curriculum, the researcher conducted post tests under the same pretest conditions, data and statistical treatment and concluded that the use of enrichment activities in the curriculum for the teaching of physical education for female students has a direct and significant impact on the learning of students, skills in question. Enrichment activities also helped to open the door for dialogue and discussion and to express opinions freely through the division of one class into small groups, which in turn helped to learn the skills studied, and the leadership of each group helped to learn the courage and strengthen the personality of the female student.Keywords: Enrichment activities, Positive thinking, High-dribble and the scoring of stability.
Differential-Pulse Polarography Method for Evaluation of Diclofenac Sodium in Pharmaceuticals Heba Y. Ahmed
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
Publisher : Journal of Global Pharma Technology

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Abstract

A reliable DPP process has been developed and applied for the estimation of Diclofenac sodium in pharmaceuticals form with DME versus Ag/AgCl. The best peak response was established a cathodic peak -1.14V in 0.002 M acetate buffer at pH5and 0.1M KCl as supporting electrolyte with four electrons transferred in irreversible process. To attain the highest sensitivity, instrumental and experimental and parameters were examined including the type and concentration of supporting electrolyte, pH, buffer solutions, pulse amplitude, and voltage step time. Diffusion current was in direct proportion to Diclofenac sodium concentration and with a linear relationship with the drug concentration in the range of (5 - 30 μg. mL-1) i.e. (1.57 × 10-5-9.4× 10-5 mol·L–1) with a correlation coefficient (r= 0.9993), detection limit (S/N = 3) was 0.85 μg. mL-1(i.e.2.67 × 10-6 mol·L–1) and the values of precision, in terms of RSD% ranged between 1.28- 4.11%.The established DPP methods offers excellent analytical figures of merits as well as applied to examine the commercial drug olfen capsule and Diclofenac sodium injection for the determination of Diclofenac sodium and found to be 99.8 mg, 76.9 mg compared to the stated value of 100mg and 75 mg respectively.Keywords: Differential-pulse polarography; Diclofenac sodium.
Comparative Study for Photocatalytic Degradation of Bromo Phenol Blue by Some Nanoparticales Semiconductors Amer Muosa Juda
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

In this study, a comparison of different types of nanocatalyst such as zinc oxide nanoparticles, copper oxide nanoparticles and magnesium oxide nanoparticles on the photocatalytic activity efficiency of Bromo Phenol blue dye. Heterogeneous photocatalytic method was utilized; it was approved out by using UV (A) as light source. Some factors influence on the rate of the photocatalytic degradation of each catalyst were studied and compared and selected the most efficient nanocatalyst. The results of many factors, (such as weight of catalyst, primary dye concentration, pH of aqueous solution, and temperature) , shows that the photodecolorization and degradation is a pseudo-first order reaction giving to the Langmuir-Hinshelwood relationship. The experiments were carried out by varying weight of catalyst (0.02–0.07 g), initial concentration of dye (50–30ppm ) , pH solution  (1-11), and temperature range(298-313)K. The optimum conditions were approximated as: pH 3 when use ZnO NPs and pH = 5 when using both of CuO NPs and MgO NPs, catalyst amount of 0.06 g,0.05,  and 0.03g for ZnO NPs, CuO NPs and MgO NPs respectively. The degradation extents of 92.85%, 65.16% and 74.18% with ZnO NPs, CuO NPs and MgO, respectively obtained for BPB during 20 min irradiation and 30ppm dye concentration. The degradation extent was monitored by UV–vis spectroscopy. The Photocdecolorazation and degradation extent was observed increase with high temperature. Arrhenius plot shows that the Ea is equal to (29.7±1, and 18.54±1, 13.9±1) kJ mol-1 by using ZnO, CuO and MgO NPs respectively. The thermodynamic parameters of the photocatalytic degradation of BPB, like Ea, ΔH*, ΔS*and ΔG*showed the efficiency of the process. The most efficient nanocatalyst ZnO NPs>MgO NPs>CuO NPs
Evaluation of the Level of Health Awareness of the Players of the Iraqi Premier League in Handball Ahmed Kadhim Abdulkareem
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The objective of researchSetting levels of the health awareness measure and its application to the players of the Iraqi Premier League handball applicants.Recognition of the level of health awareness of the players of the Iraqi Premier League handball applicants.Evaluation of the level of health awareness of the players of the Iraqi Premier League handball applicants.The researchers used the descriptive method in the survey method to determine the level of health awareness. The scale was applied in the final form to a sample of the players of the Iraqi Premier League in handball for the 2017-2018 sports season. The researchers then set levels for the health awareness measure and applied it to the players of the Iraqi league Hand, and used the researchers Statistical Bulletin of Social Sciences (SPSS) version XVII. The following conclusions were reached:Five levels of health awareness measure have been developed.The ability of the health awareness scale to be applied by the researchers in measuring health awareness.The majority of the players of the Iraqi Premier League handball a poor level in the health awareness measure.Keywords: Health awareness, Premier League and handball.
Intratumoral Co-Administration of Oncolytic Newcastle Disease Virus and Bacterial Hyaluronidase Enhances Virus Potency in Tumor Models Hasanain Sahib Salih
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

Purpose: Bacterial hyaluronidase in co delivery evaluation effect with oncolytic Newcastle Disease Virus to determine spreading of the virus throughout Adenocarcinoma tumors Models in mice, and evaluate the reduction in tumor mass by efficacy of co delivery injection in tumor models. This study aimed to define the success of Combination effect between bacterial origin hyaluronidase and Newcastle Disease Virus and compare the invasion of this combination versus treatment with hyaluronidase enzyme or with oncolytic Newcastle disease virus only.Experimental Design:Newcastle disease virus (NDV) titration 6.3x105 injected in combined dose with 200 international unit (IU)  bacterial origin hyaluronidase to provide a mass invasion efficiency and spread of Newcastle disease virus within tumors that detected through the measurement of growth inhibition of tumor mass and  immunofluorescence detection assay. The experiment performed in vivo in mice bearing AMN3 tumor cell line model. Conclusion: The data presented in this study show that combination treatment of solid tumors with an NDV and bacterial origin hyaluronidase significantly improves spread of virus through the tumor mass, resulting in prolonged survival of the tumor-bearing animals and in vivo tumor mass reduction without increasing the metastatic potential. Thus, this combination of NDV and hyaluronidase may offer a novel and promising therapy for the treatment of patients with cancer.Keyword: NDV (Newcastle Disease Virus), HA (Hyaluronic Acid), AMN3 (Ahmed Murtatha Nahi 2003 Cell Line), ECM (Extra Cellular Matrix).
Comparing the Gene ACE Variant with Some Cardiac Muscle Variables for Handball Players Nagham Salman Kareem
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

The study objective to recognize the diversity of the gene ACE and the heart variables and the researcher used the descriptive research in the survey method to identify the majority of players who have cardiac functions that distinguish them from others according to genetic diversity where the dominant gene types were identified in the sample research (DD, ID , ii) The search sample was identified and chosen in the intentional manner, the 12-player handball players of the Diwaniya Governorate, divided by shapes into DD (6) players and (II) were (3) players and finally (ID) were (3) players and a blood withdrawal test was performed for the sample P Date on Monday (5 \ 3 \ 2018) and after which the checks were performed on the ACE gene and all the players have appeared to have the gene where the genes were dominant in the sample then the gene forms were detected to know the differences between groups through any group delayed to reach fatigue and the group. The gene structure (DD) is the most delayed to reach the anaerobic threshold where the researcher attributes that the genetic structure (DD) is what distinguished this group from others and the objectives of the search is to identify the types of the ACE as well as to identify the differences between the totals of the shapes according to the variables of the heart muscle In the fields of research, the human field was the handball players of the Diwaniya Sports and Spatial club, the sports hall in the Ramadan district and the period of time between (5 \03 \ 2018) – (8 \05 \ 2018) The statistical means were used (arithmetic mean, standard deviation, Variance test (p) for the differences between totals, the Law (LSD) is the least significant difference, Simple link.Keywords: ACE I, D gene and cardiac muscle.
Characterization of Silver Nano Particles Synthesized by Leaves Green Tea Extract Neeran Obied Jasim
Journal of Global Pharma Technology Volume 10 Issue 10: 2018
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Abstract

Background and Objective: Plant extract contain biomolecules which can be a reduce metal, ions, to nanoparticles in one step n synthesis process.. Materials and Methods: green synthesis of silver nanoparticles using aqueous leaves extract of green tea and study the characters of this particles using UV -VIS spectrophotometer and SEM .Also, Investigation the antifungal activity of it. Results : silver nanoparticles were synthesized using leaf extract of green tea in present of silver nitrate and the color change to brown .UV-Vis spectrophotometer appear peak in wavelength at 420nm which is prescribed for silver nanoparticles . the microscope images by SEM, showing the size of Ag nanoparticles in range 3.6-5.3nm.Antifungal activity explain the ability of biosynthesis silver nanoparticles to inhibition the growth of yeast, C. neoformans with zone of inhibition 2.7mm compare with leaves extract in diameter 7mm.Conclusion: An extract of leaves green tea at room temperature act as reducing agent and can be used in synthesis of silver nanoparticles which have antifungal activity.Keywords: Green synthesis, Nanoparticles, Silver nanoparticles, C. neoformans.

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