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Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 52 Documents
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Search results for , issue "Volume 11 Issue 08 (2019) Aug. 2019" : 52 Documents clear
Expression of Endoglin in Bladder Carcinoma of Iraqi Patients Rawaa Al-Chalabi
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Angiogenesis is an important process for tumor growth in almost all malignancies. Endoglin (CD105) is a membrane glycoprotein, part of the TGF beta receptor complex, which strongly expressed on the surfaces of cancerous cells. It has a vital role in angiogenesis, tumor growth, survival and metastasis of cancer cells to other locations in the body. Methods: This study designed to evaluate the role of endoglin immune expression in the development of bladder carcinoma by using monoclonal antibody, 137 biopsies of bladder carcinoma were collected from patients and 42 normal bladder tissues were collected from forensic autopsy. Results: 118 (86.13%) out of 137 tumors and 27 (64.26%) of normal tissues gave positivity with different scores while other biopsies expressed negative staining pattern. Score +3 showed the highest frequency among the tumor tissues while normal bladder tissues expressed score+1 as the highest one. Conclusion: endoglin is a marker of angiogenesis closely associated with malignant potential and bladder carcinoma development.Keywords: Endoglin, Angiogenesis, Urinary bladder Carcinoma (UBC)
Executive Dysfunction in Frontotemporal Epilepsy Due to Traumatic Brain Injury Dewa Putu Gde Purwa Samatra
Journal of Global Pharma Technology Volume 11 Issue 08 (2019) Aug. 2019
Publisher : Journal of Global Pharma Technology

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Abstract

Traumatic brain injury has been recognized as a cause of epilepsy. Epilepsy could impair cognitive function and the cognitive profiles are as heterogenous as the epileptic syndromes themselves. In most idiopathic epilepsies, cognition is only mildly deteriorated or even normal, whereas symptomatic epilepsy disorders are accompanied by focal deficits according to the specific functions of the respective areas. Poor cognitive outcome is generally associated with an early onset and a long duration of the seizure and with poor seizure control. We report a 31-year-old man, with a specific generalized tonic clonic seizure during sleep since one year ago. MRI shows cystic encephalomalacia in left frontal lobe due to head trauma 3 years ago. This patient had executive function disorder which was caused by uncontrolled frontotemporal epilepsy due to traumatic brain injury. We propose AED and cognitive stimulation to be performed routinely to prevent further cognitive deterioration.Keywords: Executive function, Frontotemporal epilepsy, Traumatic brain injury.

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