cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
I Wayan Sudarsa
Contact Email
sudarsa@unud.ac.id
Phone
-
Journal Mail Official
globalpharmatechnology@gmail.com
Editorial Address
India
Location
Kota denpasar,
Bali
INDONESIA
Journal of Global Pharma Technology
Published by Universitas Udayana
ISSN : 09758542     EISSN : -     DOI : -
Core Subject : Health,
Medicine & Pharmacology
ournal of Global Pharma Technology is a monthly, open access, Peer review journal of Pharmacy published by JGPT Journal publishes peer-reviewed original research papers, case reports and systematic reviews. The journal allows free access to its contents, which is likely to attract more readers and citations to articles published in JGPT. JGPT publishes original research work that contributes significantly to the scientific knowledge in pharmacy and pharmaceutical sciences- Pharmaceutics, Novel Drug Delivery, Pharmaceutical Technology, Cosmeticology, Biopharmaceutics and Pharmacokinetics, Pharmacognosy, Natural Product Research, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmaceutical Analysis, Pharmacology, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics, Biotechnology and Applied Computer Technology. For this purpose we would like to ask you to contribute your excellent papers in pharmaceutical sciences.
Arjuna Subject : Kedokteran - Onkologi
Articles 4 Documents
 1 
Search results for , issue "Volume 13 Issue 01 (2021) Jan. 2021" : 4 Documents clear
Evaluation of In Vitro Antioxidant Activity of Ethanolic Extract from Vallaris solanacea Leave Pitchaimuthu Pandian
Journal of Global Pharma Technology Volume 13 Issue 01 (2021) Jan. 2021
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.051 KB)

Abstract

Several methods employed in evaluating antioxidant activities on varied samples gives varying results depending on the specificity of the free radical or oxidant used as a reactant. This study investigated the antioxidation /radical scavenging properties since ethanolic extraction on Vallaris solanacea leaves. Antioxidant capacity on Vallaris solanacea leaves were evaluate near measuring a DPPH photometric assay, Superoxide radical scavenging activities, Iron chelating activities, Hydroxyl radical scavenging activity, Nitric oxide radical scavenging activities, Total antioxidant activities, Ferric Reducing Ability Power (FRAP) assay, full phenol content overall flavonoids content. A concentration was 125, 250, 500, 1000 μg/ml. The standard was used according to their methods. All values are expressed for mean ± SEM for three determinations with percentage of activity (±SEM) of IC50 values. The result revealed that DPPH as 625μg/ml, Superoxide radical scavenging as 459μg/ml, Iron chelating activity as 639μg/ml, Hydroxyl radical scavenging as 556μg/ml, Nitric oxide original scavenging as 683μg/ml, Total antioxidant as 638 μg/ml, FRAP as 543μg/ml and the total phenolic , flavonoids content was 3.980±0.007 and 2.651±0.077. The findings from the study reveal that the antioxidative potentials of Vallaris solanacea leaves of ethanolic extract and could serve as free radical inhibitors, phenolic and flavonoids as possibly acting as principal antioxidantsKeywords: Vallaris solanacea antioxidant, phenols, flavonoids, free radical.
Significance of TLC and HPTLC in Phytochemical Screening of Herbal Drugs Anguraj Moulishankar; Prasanna Ganesan; Madhivanan Elumalai; Karthikeyan Lakshmanan
Journal of Global Pharma Technology Volume 13 Issue 01 (2021) Jan. 2021
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Plants provide the most of the pharmacologically active principles like alkaloids, anthraquinones, cardiac glycosides, coumarins, flavonoids, saponins, tannins, essential oils to humans. A large number of the medicinal plants were used by traditional and folk medicinal practitioners for various ailments. The active principles in them are detected by qualitative chemical tests for each category of phytoconstituents. Many chromatographic methods help in separation of the complex mixtures into individual phytoconstituent. Even though Thin Layer Chromatography (TLC) and HPTLC are rapid and easy methods, the selection of stationary phase and solvent system is always a time-consuming process. The general solvent systems for the specific category of secondary metabolites are available in various literatures, but for specific phytoconstituent one should do trial and error method to identify a suitable solvent system. This review article aims to minimize the valuable time of both beginning and experienced researchers by providing well-organized information about TLC and HPTLC in phytochemical screening. Keywords: TLC, HPTLC, Solvent system, Extraction, Phytochemical analysis, Herbal drugs.
Design and Development of Losartan Potassium Press Coated Tablets for Pulsatile Drug Delivery S Ramkanth; Ashok Kumar Janakiraman; Saminathan Kayarohanam; Vetriselvan Subramaniyan; Sinouvassane Djearamane
Journal of Global Pharma Technology Volume 13 Issue 01 (2021) Jan. 2021
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The objective of the present study was to design and evaluate time-dependent pulsatile delivery systems (PDDS) of losartan potassium pulsatile press coated tablets. Losartan potassium (LP) is angiotensin II (AG II) receptor antagonists to treat hypertension. LP pulsatile systems are time-controlled drug delivery systems which are designed to mimic the circadian rhythm of the body and deliver the drug at a specific time. LP core tablets were prepared by direct compression method using a single punch machine. The prepared tablets were shielded with a combination of different grades of Hydrosy propyl methyl cellulose (HPMC) and Ethyl cellulose (EC) as coated materials. Prepared core and pulsatile tablets were optimized and evaluated for various properties like diameter and thickness, uniformity of weight, hardness, friability, disintegration time, drug content and in vitro dissolution studies. The drug release profile LP pulsatile tablet batch of LH-3 designated as the optimized batch that shows the lag time 8 hrs with complete drug release of 99%. LP pulsatile tablets will be taken at bedtime, releasing the drug in the morning hrs when the symptoms are more prevalent can prove to be a revolution in the treatment of hypertension.
Preformulation Parameters Characterization towards Design, Development and Formulation of Etodolac Loaded Nanoparticles Saminathan C
Journal of Global Pharma Technology Volume 13 Issue 01 (2021) Jan. 2021
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The purpose of the present study was to systematically investigate some of the important physicochemical properties of Etodolac loaded nanoparticles. Etodolac is a non-steroidal anti-inflammatory drug, is used to manage rheumatoid arthritis associated symptoms. Almost all drugs are marketed as tablets, capsules or both. Prior to the development of these major dosage forms, it is essential that pertain fundamental physical and chemical properties of the drug molecule and other divided properties of the drug powder are determined. This information decides many of the subsequent events and approaches in formation development. A modified release nanoparticle of Etodolac was prepared by solvent evaporation method using EUTRAGIT RS 100 as coating material. Hence along with selection of excipients, the preformulation study of drug Etodolac is completed for successful formulation of modified release nanoparticles. Preformulation studies included solubility, pKa, dissolution, melting point, assay development, stability in Solution, stability in solid state; microscopy, bulk density, flow properties, excipients compatibility, entrapment efficiency and release profile of nanoparticles were investigated. The experimental values and results of this study will be presented. Keywords: Nanoparticles, Entrapment efficiency, Etodolac, EUTRAGIT RS 100, Preformulation.

Page 1 of 1 | Total Record : 4

 1 

Filter by Year

2021 2021


Reset
Filter By Issues
All Issue Volume 17 Issue 12 (2025) Dec. 2025 Volume 17 Issue 11 (2025) Nov.2025 Volume 17 Issue 10 (2025) Oct. 2025 Volume 17 Issue 04 (2025) April 2025 Volume 17 Issue 03 (2025) March 2025 Volume 17 Issue 02 (2025) Feb. 2025 Volume 17 Issue 01 (2025) Jan 2025 Volume 16 Issue 12 (2024) Dec. 2024 Volume 16 Issue 11 (2024) November 2024 Volume 16 Issue 10 (2024) October 2024 Volume 16 Issue 09 (2024) September 2024 Volume 16 Issue 08 (2024) August 2024 Volume 16 Issue 07 (2024) July 2024 Volume 16 Issue 06 (2024) June 2024 Volume 16 Issue 05 (2024) May 2024 Volume 16 Issue 04 (2024) April 2024 Volume 16 Issue 03 (2024) March 2024 Volume 16 Issue 02 (2024) February 2024 Volume 16 Issue 01 (2024) January 2024 Volume 14 Issue 05 (2022) May 2022 Volume 13 Issue 05 (2021) May 2021 Volume 13 Issue 04 (2021) April 2021 Volume 13 Issue 03 (2021) March 2021 Volume 13 Issue 02 (2021) Feb. 2021 Volume 13 Issue 01 (2021) Jan. 2021 Volume 12 Issue 12 (2020) Dec. 2020 Volume 12 Issue 11 (2020) Nov. 2020 Volume 12 Issue 10 (2020) Oct. 2020 Volume 12 Issue 09 (2020) Sept. 2020 Volume 12 Issue 08 (2020) Aug. 2020 Volume 12 Issue 07 (2020) July 2020 Volume 12 Issue 06 (2020) June 2020 Volume 12 Issue 05 (2020) May 2020 Volume 12 Issue 04 (2020) April 2020 Volume 12 Issue 03 (2020) March 2020 Volume 12 Issue 02 (2020) Feb. 2020 Volume 12 Issue 01 (2020) Jan. 2020 Volume 12 Issue 08 Volume 11 Issue 12 (2019) December 2019 Volume 11 Issue 11 (2019) November 2019 Volume 11 Issue 10 (2019) October 2019 Volume 11 Issue 09: (2019) September 2019 Volume 11 Issue 09 (2019) September 2019 Volume 11 Issue 08 (2019) Aug. 2019 Volume 11 Issue 07 (2019) July 2019 Volume 11 Issue 06 (2019) June 2019 Volume 11 Issue 05 (2019) May 2019 Volume 11 Issue 04 (2019) April 2019 Volume 11 Issue 03 (2019) March. 2019 Volume 11 Issue 02 (2019) Feb. 2019 Volume 11 Issue 01 (2019) Jan. 2019 Volume 11 Issue 2: 2019 Volume 10 Issue 12. Volume 11 Issue 6. Volume 10 Issue 12 (2018) December 2018 Volume 10 Issue 11 (2018) November 2018 Volume 10 Issue 10 (2018) October 2018 Volume 10 Issue 09: (2018) September 2018 Volume 10 Issue 08: (2018) August 2018 Volume 10 Issue 07: (2018) July 2018 Volume 10 Issue 06: (2018) June 2018 Volume 10 Issue 05: (2018) May2018 Volume 10 Issue 04: (2018) April 2018 Volume 10 Issue 02: (2018) Feb 2018 Volume 10 Issue 01: (2018) Jan. 2018 Volume 10 Issue 10: 2018 Volume 10 Issue 01 Volume 09 Issue 12 Volume 09 Issue 11 Volume 9 Issue 11 . Vol. 9 Issue 7 : 2017 Volume 9 Issue 10 Volume 09 Issue 09 Volume 09 Issue 08 Volume 9 Issue 07 Volume 09 Issue 05 Volume 09 Issue 04 Volume 09 Issue 03 Volume 09 Issue 02 Volume 08 Issue 11 Volume 08 Issue 07 Volume 08 Issue 06 Volume 08 Issue 05 Volume 08 Issue 04 Volume 08 Issue 03 Volume 08 Issue 02 Volume 08 Issue 01 Volume. 9 Issue 6 Volume 08 Issue 10: (2016) October 2016 Volume 08 Issue 09: (2016) September 2016 Volume 12 Issue 01 Volume 11 Issue 07 Volume 11 Issue 05. Volume 11 Issue 04. Volume 11 Issue 03 Volume 11 Issue 01. Volume 08 Issue 08 Volume 04 Issue 02: (2012) February 2012 Volume 03 Issue 06: (2011) June 2011 Volume 03 Issue 04: (2011) April 2011 Volume 02 Issue 10: (2010) Oct.2010 Volume 02 Issue 07: (2010) July 2010 Volume 02 Issue 05: (2010) May 2010 Volume 02 Issue 03: (2010) March 2010 More Issue