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Asian Journal of Toxicology, Environmental, and Occupational Health
Published by Institute for Advanced Science, Social, and Sustainable Future
ISSN : -     EISSN : 30253675     DOI : -
Core Subject : Health, Science,
Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary
Asian Journal of Toxicology, Environmental, and Occupational Health (AJTEOH) is an interdisciplinary journal that publishes material on all aspects of public health science which concern to toxicology, environmental, and occupational relation. AJTEOH is a peer-review journal published by Institute for Advanced Science, Social, and Sustainable Future. The journal welcomes high-impact articles on emerging public health science that covers human toxicology, pesticide hazard, behavior relation to occupational health and safety, environmental health risk assessment, occupational stress, and mental health, waste management; water, air, and soil pollution. The journal has a major focus on Asia but articles from other countries are accepted provided that the implications for Asia’s countries are addressed. The journal is multidiscilinary and aims to publish methodologically sound research from any of the academic disciplines that constitute human toxicology, pesticide hazard, behavior relation to occupational health and safety, environmental health risk assessment, occupational stress, and mental health, waste management; water, air, and soil pollution
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol. 2 No. 1: (July) 2024" : 5 Documents clear
A ecological study of galamsey activities in Ghana and their physiological toxicity Ofori, Samuel Ayetibo; Dwomoh, Joshua; Yeboah, Enoch Owusu; Aggrey, Martin Leo; Nti, Samuel; Philip, Amankwah; Asante, Clement
Asian Journal of Toxicology, Environmental, and Occupational Health Vol. 2 No. 1: (July) 2024
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/ajteoh.v2i1.2024.395

Abstract

Background: Small-Scale Small-Scale Gold Mining (ASGM), locally known as "galamsey," has emerged as a pervasive issue in Ghana characterized with environmental degradation, land and water resource depletion, health hazards for miners, social and economic impacts. This comprehensive review explores the ecological and health effects of galamsey operations across different regions of the country. Methods: The study employs a systematic analysis method to examine the available literature from 2000 to 2023. Various academic databases, including PubMed, Google Scholar, JSTOR, and relevant government publications, were searched to gather relevant information. Findings: The review reveals that galamsey has had significant ecological consequences, including deforestation, habitat destruction, water pollution, and soil degradation, which have adversely affected Ghana's natural beauty. Moreover, the study highlights the physiological health issues faced by galamsey miners, such as accidents, physical strain, mental strain, kidney problems, respiratory disorders, and metabolic diseases. The presence of elevated levels of mercury, cyanide, arsenic, and cadmium in both the environment and the human body are directly linked to ASGM in Ghana. About seventy percent (70%) of the houses in ASGM community relied on surface water, and all of the homes utilized the fields or bush as their main toilet. Conclusion: Implementing remote sensing, geospatial technologies, promoting clean mining technologies, integrating environmental conservation, occupational safety and public health awareness are key technical and innovative measures to mitigate galamsey in Ghana. Novelty/Originality of this article: This study proposes an integrated approach to address the impacts of galamsey, combining remote sensing and geospatial technologies with public health and environmental conservation programs. The model can provide a comprehensive understanding of the spatial and temporal impacts of ASGM and enable more targeted interventions.
Analysis of the relationship between attitudes, training, and perceptions of food handlers on supervision and the implementation of personal hygiene among food handlers Rahmalia, Vina
Asian Journal of Toxicology, Environmental, and Occupational Health Vol. 2 No. 1: (July) 2024
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/ajteoh.v2i1.2024.921

Abstract

Background: Poor personal hygiene can affect the cleanliness of food provided to patients. A preliminary study conducted at XX Hospital Nutrition Installation found that five food handlers failed to use complete personal protective equipment (PPE), and two food handlers engaged in conversation while preparing food. This research aims to identify factors influencing the implementation of personal hygiene among food handlers at XX Hospital Nutrition Installation. Method: This quantitative study employed a cross-sectional design from November 2019 to March 2020. The sample included 43 food handlers selected through total sampling. Data analysis utilized SPSS and Chi-square tests. Results: The study indicated that 48.8% of food handlers exhibited inadequate personal hygiene, 41.9% had limited knowledge, 53.5% demonstrated negative attitudes, 60.5% did not receive training, and 51.2% perceived inadequate supervision from their superiors. Significant correlations were observed between knowledge (p=0.004), attitude (p=0.000), training (p=0.000), and perception of supervision (p=0.004) with the implementation of personal hygiene. Conclusion: Attitude, training, and perception of supervision significantly influence the adherence to personal hygiene among food handlers at XX Hospital 's Nutrition Installation. It is recommended that the Nutrition Installation enhance supervision of food handlers' personal hygiene and conduct certified training programs on food hygiene and sanitation. Novelty/Originality: This study provides new insights into the relationship between knowledge, attitudes, training, and perceptions of supervision with implementing personal hygiene in the context of hospital food handlers. The findings suggest that although multiple factors influence individual hygiene, a better training and supervision-based approach can significantly improve compliance with hygiene practices, which is an essential contribution to managing food quality in the hospital environment.
Factors contributing to work fatigue among nurses at hospital: A study on the impact of work attitudes, shift schedules, and sleep quality Diana, Tyra Septi
Asian Journal of Toxicology, Environmental, and Occupational Health Vol. 2 No. 1: (July) 2024
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/ajteoh.v2i1.2024.937

Abstract

Background: Fatigue is an essential body protection mechanism, preventing further damage and allowing recovery after rest. In work, especially in the hospital environment, fatigue can affect the performance and well-being of medical personnel, including nurses. This study aims to identify and analyze factors associated with work-related fatigue among Dr. Adjidarmo Regional Hospital nurses. The main focus of this study includes the relationship between gender, length of service, work attitude, shift schedule, and sleep quality on the level of fatigue experienced by nurses. Method: This study adopted a cross-sectional design targeting a population of 256 nurses who are actively practicing at Dr Adjidarmo Regional Hospital. The study sample consisted of 75 respondents selected using a random sampling method. Data was collected through questionnaire-based interviews that accessed information from secondary and primary sources. The data obtained were analyzed univariate and bivariate to determine the prevalence and significant relationship between the variables studied and work-related fatigue. Findings: Univariate analysis revealed that out of 75 respondents, 54.7% reported experiencing moderate work-related fatigue. Demographic distribution showed that 74.7% of respondents were female, 81.3% had worked for five years or more, 50.7% showed risky work attitudes, 29.3% worked night shifts, and 52.0% reported poor sleep quality. The results of the bivariate analysis showed a significant relationship between work attitudes (P-value = 0.000), shift schedules (P-value = 0.002), and sleep quality (P-value = 0.000) with the level of work-related fatigue. Conclusion: Based on these findings, it is recommended that shift schedules be distributed evenly during the third shift to reduce nurse fatigue. In addition, stretching exercises and physical activity during work breaks should be encouraged to improve nurses' well-being and reduce fatigue-related problems. This intervention aims to improve nurses' working conditions, which can improve patient care quality and reduce fatigue's negative impact on work performance. Originality/Novelty: This study offers new insights into factors contributing to work-related burnout among nurses, focusing on specific variables such as work attitudes, shift schedules, and sleep quality. The study identifies significant correlations that have not been widely explored in the context of a regional hospital in Indonesia. By providing practical recommendations for redistributing shift schedules and promoting stretching exercises, this study contributes to the development of evidence-based intervention strategies to address burnout in the hospital workplace.
The impact of valproic acid administration: Effects on the growth of tongue cancer cells Rasiani, Salma
Asian Journal of Toxicology, Environmental, and Occupational Health Vol. 2 No. 1: (July) 2024
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/ajteoh.v2i1.2024.939

Abstract

Background: Tongue cancer represents the predominant malignancy within the oral cavity (25 – 40% of squamous cell carcinoma), necessitating treatment modalities such as surgery, radiotherapy, and chemotherapy. Valproic acid, an antiepileptic medication, functions as a histone deacetylase inhibitor or activator of anti-tumor signaling pathways. Objective: To deepen our understanding of the effects of valproic acid on the viability, cytotoxicity, proliferation, and migration capabilities of HSC-3 cells. Method: This study employed an in vitro laboratory approach, exposing HSC-3 cells to valproic acid. The experimental groups included a negative control with culture media devoid of valproic acid, and treatment groups exposed to valproic acid at concentrations of 145 ppm, 180 ppm, and 355 ppm, respectively. Results: Significant differences (p-value < 0.05) were observed between HSC-3 cells treated with valproic acid (145 ppm, 180 ppm, and 355 ppm) and the control group in terms of viability, cytotoxicity, proliferation, and migration. Reduced cell viability, increased cytotoxicity, and decreased proliferation were noted. Migration assays indicated suppressed migration of HSC-3 cells.  Conclusion: In summary, this study reveals that valproic acid exerts substantial effects on various aspects of HSC-3 cell behavior. It decreases cell viability, enhances cytotoxicity, suppresses proliferation, and inhibits cell migration. These findings highlight the potential of valproic acid as a therapeutic agent for tongue cancer by targeting crucial cellular processes involved in cancer progression. Further research and clinical trials are essential to confirm these effects and explore their application in cancer treatment strategies. Novelty/Originality of this article:: This study shows valproic acid has potential as a therapeutic agent for tongue cancer by decreasing cell viability, increasing cytotoxicity, suppressing proliferation, and inhibiting migration of HSC-3 cells. These findings introduce a new application of valproic acid as an anticancer agent, expanding the use of antiepileptic drugs. This study opens up opportunities for developing more effective tongue cancer therapies and encourages further research and clinical trials to validate these findings.
Characterization of waste composition as a basis for developing a community-based 3R TPS system in waste management efforts Aprilia, Reza; Noerhayati, Eko; Rahmawati, Anita
Asian Journal of Toxicology, Environmental, and Occupational Health Vol. 2 No. 1: (July) 2024
Publisher : Institute for Advanced Science, Social, and Sustainable Future

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61511/ajteoh.v2i1.2024.1010

Abstract

Background: The issue of waste management has become a major concern in many regions, including Pandansari Lor Village, Malang Regency. To address this challenge, it is necessary to develop an effective waste management system that involves the active participation of the community. This study aims to determine the waste composition in Pandansari Lor Village as a basis for developing a 3R (Reduce, Reuse, and Recycle) Waste Transfer Station system that is tailored to the needs of the community. Method: The research methodology includes primary data collection through sampling and analysis of waste composition, as well as secondary data collection from relevant sources. Findings: The results show that the waste composition in Pandansari Lor Village is dominated by organic waste, including food waste (58.42%) and garden waste (3.84%), followed by plastic waste (26.74%), paper waste (5.89%), and other types of waste. Conclusion: These findings provide valuable insights for the design and implementation of a community-based 3R Waste Transfer Station system that can effectively manage the waste generated in the village. The proposed system aims to maximize resource recovery, reduce the amount of waste sent to landfills, and promote sustainable waste management practices within the community. Novelty/Originality of this article: This study develops a waste disposal model tailored to the specific waste composition of the village, focusing on processing organic waste into high-quality compost and recycling plastic into products of economic value. The model also integrates a community-based education system to increase participation in waste sorting at source.

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