cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Patricia Wulandari
Contact Email
phloxinstitute@gmail.com
Phone
+6287788090173
Journal Mail Official
sjog.editor@gmail.com
Editorial Address
Jl. Sirna Raga, Delapan Ilir, Ilir Timur Tiga, Palembang, South Sumatera, Indonesia
Location
Kota palembang,
Sumatera selatan
INDONESIA
Sriwijaya Journal of Obstetrics and Gynecology
Published by Phlox Institute: Indonesian Medical Research Organization
ISSN : 29869838     EISSN : 29869838     DOI : https://doi.org/10.59345/sjog
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health
Focus Sriwijaya Journal of Obstetrics and Gynecology (SJOG) focused on the development of medical sciences especially obstetrics and gynecology for human well-being. Scope Sriwijaya Journal of Obstetrics and Gynecology (SJOG) publishes articles which encompass all aspects of basic research/clinical studies related to the field of obstetrics - gynecology and allied science fields, especially all type of original articles, case reports, review articles, narrative review, meta-analysis, systematic review, mini-reviews and book review.
Arjuna Subject : Kedokteran - Obstetrics and Gynaecology
Articles 25 Documents
 1   2   3 
Exploring the Pathophysiology of Adenomy osis in Jakarta: Novel Insights into I nflammatory Pathways and Angiogenesis Suryani, Febria; Rodriguez, Maria
Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 1 (2023): Sriwijaya Journal of Obstetrics and Gynecology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjog.v1i1.214

Abstract

Introduction: Adenomyosis, characterized by endometrial glands and stroma within the my ometrium, is a significant cause of morbidity (abnormal uterine bleeding (AUB), pain, infertility) among women globally. While its general pathophysiol ogy is increasingly understood, population-specific data, particularly f rom diverse Asian populations like that of Jakarta, Indonesia, remains limited. This study aimed to investigate the roles of specific inflammatory pathways and angiogenic factors in adenomyosis within a cohort of women in Jakarta, hypothesizing that common pathogenic mechanisms manifest in this population, potentially influenced by local factors. Methods: This prospective c ase-control study was conducted in three tertiary referral hospitals in Jakarta, Indonesia from January 2022 to December 2024. Fifty women undergoing hysterectomy, diagnosed with adenomyosis were recruited, alongside 50 cont rol women without adenomyosis undergoing hysterectomy for other benign conditions. Samples of eutopic endometrium, ectopic adenomyotic lesions, and associated myometrium were collected. Immunohistochemistry quantified inflamm atory cells (macrophages, mast cells, T-lymphocytes) and microvessel density (CD31). Expression of key inflammatory cytokines and angiogenic factors was assessed via qRT-PCR and ELISA. Results: Women with adenomyosis in th e Jakarta cohort exhibited significantly increased infiltration of M1-phenotype macrophages (p0.001) and mast cells (p0.001) in adenomyotic lesions and eutopic endometrium compared to controls. IL-6, TNF-α, and MCP-1 expression was markedly upregulated in adenomyotic foci (all p0.001). Microvessel density, VEGF-A, and VEGFR2 expression were significantly elevated in adenomyotic tissue (all p0.001). Strong positive correlations were observed between macrophage density, IL-6 levels, VEGF-A expression, and microvessel density within adenomyotic lesions, similar to findings in other populations. Conclusions: This study, conducted in Jakarta, provides strong evidence for a heightened pro-inflammatory and pro-angiogenic microenvironment in adenomyosis, consistent with general pathogenic theories. These findings i n an Indonesian population underscore the universal importance of th ese pathways and suggest that novel therapies targeting inflammation and angiogenesis could be relevant for women in this region. Further research should explore potential local modulatory factors.
The Overview of Menstrual Physiology: A Narr ative Literature Review Andini, Kusuma
Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 1 (2023): Sriwijaya Journal of Obstetrics and Gynecology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjog.v1i1.215

Abstract

Menstruation is a physiological or normal condition, namely events of the production of bl ood, mucus, and cell waste periodically originate from the uterine mucosa and occur relatively regularly from menarche until menopause, exc ept during pregnancy and lactation. Menstruation is the result of very n eat and standard cooperation from the hypothalamus-pituitary-ovarian endocrine axis. Hypothalamus spurs the pituitary gland by secreting gonad otropin-releasing hormone (GnRH), a deca-peptide secreted pulsatively by the hypothalamus. Menstruation is considered normal if it occurs between 22-35 days. Disturbance menstruation is most common at the beginning and end of the reproductive period, namely in those under 19 years of age and over 39 years of age. These disturbances may be related to the length of t he menstrual cycle or the number and duration of menstruation. One person Women can experience both disorders. This literature review aimed to describe the menstrual cycle physiologically and the disorders that accompany it.
The Relationship between Risk Factors for the Use of Oral Contraception and Sexual Activity with Cervical Cancer Incidence at Dr. M Djamil General Hospital, Padang, Indonesia Hidayat, Ahmad; Syifa
Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 1 (2023): Sriwijaya Journal of Obstetrics and Gynecology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjog.v1i1.216

Abstract

Introduction: Cervical cancer is a malignancy of the cervix caused by the human papilloma virus (HPV). Cervical cancer often has no symptoms. Most patients are known to be positive for cervical cancer at an advanced stage. This study aim ed to determine the relationship between the use of oral contraceptives a nd sexual activity with the incidence of cervical cancer at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: This study was an analytic observational case-control study. A total of 37 subjects were researched as a case group and a total of 111 subjects as a control group. This study made observations of variable age, Education, work, use of oral contraceptives, and sexual activity for the first time. Data analysis was carried out using SPSS software univariate and bivariate. Results: Use of oral contracepti ves ≥ 5 years was not significantly associated with the incidence of cervical cancer, p> 0.05. Age at first sexual intercourse <18 years was signif icantly associated with the incidence of cervical cancer, p<0.05. Age at first pregnancy <18 years was significantly associated with the incidence of cervical cancer, p<0.05. Conclusion: Sexual activity is a risk factor that plays a role in the incidence of cervical cancer at Dr. M Djamil General Hospital, Padang, Indonesia.
An Overview and Management of Painful Menstrual Disorder (Dysmenorrhea): A Narrative Literature Review Juntu, Petrus; Ananta, Gede
Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 1 (2023): Sriwijaya Journal of Obstetrics and Gynecology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjog.v1i1.217

Abstract

Primary dysmen orrhea is menstrual pain associated with the release of prostaglandins in the ovulatory cycle, but not with the pelvic disease. Approximately 9 0% of all women experience dysmenorrhea, 15% of whom are unable to last 1 to 3 days because of the severity of the pain. This literature review aimed to describe an overview and management of dysmenorrhea. Primary dysmenorrhea usually begins with the onset of ovulation cycles, with the highest prevalence in adolescence. In contrast, secondary dysme norrhea is associated with pelvic pathology (i.e., ovarian cysts, adenomyosis, endometriosis) that manifests in later reproductive years and can oc cur at any point in the menstrual cycle. Administration of nonsteroidal ant i-inflammatory drugs (NSAIDs) is the treatment of choice because these drugs reduce the activity of the cyclooxygenase (COX) enzyme and, thus, the p roduction of prostaglandins. NSAIDs work in the majority of women with primary dysmenorrhea and are most effective when started at the first sign of b leeding or cramping.
Overview of Risk Factors for Ectopic Pregnancy at Dr. M. Djamil General Hospital, Padang, Indonesia Rozali, Azwar; Asnawi, Zainuddin
Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 1 (2023): Sriwijaya Journal of Obstetrics and Gynecology
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjog.v1i1.218

Abstract

Introduction: Ectopic pregnancy is an emergency condition that is the cause of maternal death during the first trimester of pregnancy. Most extrauterine implantations occur in the fallopian tubes. This study aimed to find an overview factor risk of ectopic pregnancy at Dr. M Djamil General Hospital, Padang, Indonesia. Methods: This study was a descriptive observational study and used secondary data from medical record data at the medical record installation of Dr. M Djamil General Hospital, Padang, Indonesia. A total of 100 research subjects participated in this study, and the research subjects met the inclusion criteria. The inclusion criteria in this study were patients with ectopic pregnancy disorders who were treated at Dr. M Djamil General Hospital, Padang, Indonesia, over 18 years of age and had complete medical record data. Data analysis was carried out using SPSS software version 25. Univariate analysis was performed to present the distribution frequency data for each variable test. Results: The majority of research subjects had an age range of 26-35 years (55%). The most common risk factors in this study were a history of abortion in a previous pregnancy (47%), parity 0 (46%), and abortion occurring in the first pregnancy (35%). Conclusion: Maternal age, history of abortion, parity, and gravidity are risk factors that play a role in the incidence of ectopic pregnancy at Dr. M Djamil General Hospital, Padang, Indonesia.

Page 3 of 3 | Total Record : 25

 1   2   3 

Filter by Year

2023 2025


Reset
Filter By Issues
All Issue Vol. 3 No. 1 (2025): Sriwijaya Journal of Obstetrics and Gynecology Vol. 2 No. 2 (2024): Sriwijaya Journal of Obstetrics and Gynecology Vol. 2 No. 1 (2024): Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 2 (2023): Sriwijaya Journal of Obstetrics and Gynecology Vol. 1 No. 1 (2023): Sriwijaya Journal of Obstetrics and Gynecology