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Neurona
Published by Perhimpunan Dokter Spesialis Neurologi Indonesia
ISSN : 02166402     EISSN : 25023748     DOI : https://doi.org/10.52386/neurona
Core Subject : Health, Science,
Health Professions Medicine & Pharmacology Neuroscience
Neurona merupakan satu-satunya jurnal yang memuat perkembangan penelitian dan kasus terbaru bidang neurosains oleh Perhimpunan Dokter Spesialis Saraf (PERDOSSI) Pusat di Indonesia. Jurnal ini diterbitkan bulan Maret, Juni, September dan Desember. Bidang studi cakupan NEURONA meliputi: Stroke dan Pembuluh darah Neurotrauma Neuroonkologi Neuro Infeksi Neuro Behavior Neurorestorasi Neuropediatri Gangguan Tidur Nyeri Kepala Neurootologi Neuro Intervensi Neuro Intensif Neurogeriatri Gangguan Gerak Epilepsi Neuro Epidemiologi
Arjuna Subject : Kedokteran - Neurologi Klinis
Articles 11 Documents
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Search results for , issue "Vol 38 No 2 (2021)" : 11 Documents clear
PRESERVASI FUNGSI NEUROKOGNITIF PADA PASIEN METASTASIS OTAK YANG MENJALANI RADIOTERAPI Ayu Santika Santaningrum; Henry Kodrat
NEURONA Vol 38 No 2 (2021)
Publisher : PERDOSNI

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Abstract

Brain metastasis is a major factor of mortality and morbidity in cancer patients, leading to poor prognosis in patient survival. Whole-brain radiotherapy (WBRT) has remained preferred therapy to prolong survival in patients with brain metastases. Neurocognitive decline due to WBRT affects the quality of life of patients, thus encouraging development of techniques and strategies in radiation therapy for brain metastatic patients. Stereotactic radiosurgery (SRS) shows its ability to preserve cognitive function and improve quality of life in patients with limited number of intracranial metastatic lesions, with better survival at age ≤50 years. For patients who undergo WBRT, hippocampal avoidance (HA)-WBRT technique, addition of memantine, or combination of both showed significantly better neurocognitive preservation, without affecting toxicity and survival in patients with brain metastases. Keywords: brain metastases, hippocampal avoidance, memantine, stereotactic radiosurgery, whole-brain radiotherapy

Page 2 of 2 | Total Record : 11

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