Jurnal MedScientiae
Jurnal MedScientiae adalah jurnal yang dikelola oleh Fakultas Kedokteran dan Ilmu Kesehatan Universitas Kristen Krida Wacana. Jurnal ini mempublikasikan artikel-artikel secara open access dalam lingkup bidang kedokteran dan kesehatan seperti kedokteran dasar, bioetika kedokteran, biologi sel, biologi molekuler, genetika, fisiologi, biokimia, bioinformatika, anatomi, farmakologi, kesehatan masyarakat, dan ilmu biomedik lainnya. Tim editorial menerima naskah berupa artikel penelitian, literature dan systematic review, dan laporan kasus. Naskah yang dikirimkan hendaknya belum pernah diterbitkan sebelumnya di jurnal maupun media yang lain dan disiapkan sesuai dengan template atau format yang telah ditentukan. Setiap naskah yang memenuhi kriteria jurnal akan direview oleh pakar yang sesuai (peer reviewer). Jurnal MedScientiae tidak mengenakan biaya selama proses mulai dari penerimaan naskah hingga publikasi. Jurnal MedScientiae terbit 3 kali dalam satu tahun, yaitu pada bulan April, Agustus dan Desember dengan cakupan keilmuan yang telah disebutkan di atas. Edisi pertama jurnal akan diterbikan di bulan Mei tahun 2022 dengan nomor ISSN 2829-1166.
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<![CDATA[Sensitivitas Fosfomycin pada ISK Akibat Infeksi Enterobacteriaceae Penghasil ESBL pada Pasien di RS X Tahun 2023 ]]>
<![CDATA[William Dharma Wijaya]]>;
<![CDATA[Layanto, Nicolas]]>;
<![CDATA[Dharmawan, Ade]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3575
<![CDATA[Urinary tract infection (UTI) is one of the most common infections in humans. However, intensive and extensive use and misuse of antibiotics over the past 50 years such as in the use of carbapenems, resistance to antibiotics increased dramatically in recent years, especially in Enterobacteriaceae. This study aims to determine the sensitivity of fosfomycin as an drug option in treating UTI due to Extended-spectrum-β-Lactamase (ESBL)-producing Enterobacteriaceae in the era of increasing antibiotic resistance. This study is an analytical descriptive study with a cross-sectional observational design, by looking at the sensitivity pattern of ESBL-producing Enterobacteriaceae causing UTI at a certain point in time. This study used secondary data in the form of microbiology laboratory results at Hospital X in 2023. The results showed that ESBL-producing Enterobacteriaceae causing urinary tract infections were dominantly found Escherichia coli (79.41%). The level of fosfomycin sensitivity to non-ESBL-producing and ESBL-producing Enterobacteriaceae is very good and there are no significant differences in the results of the use of fosfomycin in urinary tract infections due to non-ESBL-producing and ESBL-producing Enterobacteriaceae, with the percentage being (91.31%) and (91.17%). Thus fosfomycin can be a drug option in treating UTI due to ESBL-producing Enterobacteriaceae infection.]]>
<![CDATA[Gambaran Tingkat Kecemasan Dengan Nilai Ujian Pada Mahasiswa Angkatan 2021 Fakultas Kedokteran Ukrida Jakarta Tahun 2024 ]]>
<![CDATA[Saputra, Roy]]>;
<![CDATA[Hartono, Budiman]]>;
<![CDATA[Osya Farfar, Inggrid]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3604
<![CDATA[ Faculty of Medicine students spend more time of education than other faculties students, so it is more demanding academically and emotionally and are known to experience a fairly high incidence of psychological distress. This distress has an impact on academic performance and confidence of the students. This study aims to find out the overview of anxiety with exam grades experienced by students of the Faculty of Medicine class of 2021. This study uses a descriptive observational method. Primary data was obtained from a questionnaire with the Hamilton Anxiety Rating scale, with the number of samples required amounting to 59 respondents who met the inclusion and exclusion criteria. Based on the data obtained, the majority of respindents prepared themselves the day before the exam, in the first and second exams, the majority of respondents did not experience anxiety, but at the same time, the failure rate was more than 50% with the main factor of anxiety being the exam materials that were too difficult and/or lack of time to study. There has been an increase in grades from the first, second and the herr of Integration exams. In the Skills Lab Exam, 71% respondents did not experience anxiety with failure rate of 5% of the total respondents, with the main factor of anxiety being the examiner factor. It was concluded in this study that anxiety did not have a significant impact on the exam results.]]>
<![CDATA[Rasionalitas Penggunaan Obat Benzodiazepine oleh Dokter Selama 10 Tahun Terakhir: Sebuah Literature Review ]]>
<![CDATA[Anughrahani, Lilie]]>;
<![CDATA[Wijaya, Diana]]>;
<![CDATA[Ndraha, Suzanna]]>;
<![CDATA[Rumawas, Marina Astrid]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3651
<![CDATA[Mental disorders have become a common problem globally. The World Health Organization shows that more than one in six people experienced mental health problems in 2016. Benzodiazepines, a drug that has been on the market since 1957, are often used to treat mental and behavior-related problems. Although effective for certain conditions, long-term use of benzodiazepines can cause significant side effects. Health regulations and guidelines suggest that treatment with benzodiazepines should be carried out rationally with reference to the Decree of the Minister of Health of the Republic of Indonesia in 2021 concerning the National Formulary. This literature aims to conduct a review to evaluate the rationality of the use of benzodiazepines by doctors in various countries over the past ten years. The method in this study is to search for articles through Google Scholar and Pubmed. The results obtained were that benzodiazepines are generally used to treat anxiety and sleep disorders. The maximum dose, which is according to the national formulary and the Food and Drug Administration, does not have a significant difference. Challenges that need to be addressed involve aspects of prescribing, such as ensuring the recipe is in accordance with the right indications, adhering to dosage restrictions, and paying attention to the maximum duration of use. Therefore, there needs to be clear rules to regulate this, supported by active socialization efforts to increase doctors' understanding and compliance with more rational prescribing practices. ]]>
<![CDATA[The Prevalence Rate Of Anisometropia Among Students Of FKIK Ukrida Class 2023 ]]>
<![CDATA[Ramadhan, Dafa Zahara]]>;
<![CDATA[FarFar, Inggrid Osya]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3675
<![CDATA[Anisometropia is a different refractive power between the two eyes. Anisometropia can cause various symptoms, such as eye fatigue, headaches, blurred vision, diplopia (double vision), and decreased depth of vision (stereopsis). This will definitely interfere with learning activities, especially in college students. Purpose: This study aims to determine the prevalence and characteristics of anisometropia in university students. Methods: This study used total sampling technique with cross sectional method with 150 patients as respondents. Data collection time in this study was conducted from August 2023 to September 2023. Results: In this study as many as 66.7% (100 people) experienced anisometropia. A total of 12.7% (19 people) experienced simple myopic anisometropia, as many as 2% (3 people) experienced simple hypermetropic anisometropia, as many as 8% (12 people) experienced simple myopic astigmatism, as many as 12% (18 people) experienced compound myopic anisometropia, as many as 31.3% (47 people) experienced compound myopic astigmatism anisometropia, as many as 7% (1 person) experienced mixed anisometropia. Conclusion: The prevalence of anisometropia in this study was 66.7% (100 people). The most common type of anisometropia in this study is compound myopic astigmatism. From this study, it is hoped that it can increase public awareness to carry out sharp vision checks early on, so that learning activities can be more effective.]]>
<![CDATA[Prevalensi Akomodasi Insufisiensi pada Mahasiswa Fakultas Kedokteran dan Ilmu Kesehatan UKRIDA Angkatan 2023 ]]>
<![CDATA[Gosali, Vincentio Owen]]>;
<![CDATA[Farfar, Inggrid Osya]]>;
<![CDATA[Silaen, Desi Hartati]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3690
<![CDATA[Accommodation insufficiency is an accommodation disorder characterized by a lower accommodation amplitude than the minimum limit of the Hofstetter formula. Symptoms of accommodation are impaired near vision, asthenopia (eye fatigue), blur, headache, and visual discomfort. This study aims to determine the prevalence of accommodation insufficiency in FKIK UKRIDA students class of 2023. This study used descriptive quantitative research method and cross sectional research design with 150 respondents. Each subject was only observed once at the same time using the RAF Rule as a measuring instrument. Data collection was carried out from September to November. The prevalence of accommodation insufficiency in FKIK UKRIDA Batch 2023 students amounted to 2 people (1.3%) in both eyes, 6 people (4%) in the left eye, and 2 people (1.3%) in the right eye. Accommodation disorders can be influenced by age and refraction. The prevalence of accommodation insufficiency in FKIK UKRIDA students of 2023 is 1.3%. The highest number who experienced accommodation insufficiency was in the left eye, which was 4%. It is recommended that people pay more attention to their eye health by conducting routine eye examinations every 6 months-1 year.]]>
<![CDATA[Tinjauan Pustaka Terbaru Peran Omega 3 Pada Dry Eye ]]>
<![CDATA[Anugrahsari, Santi]]>;
<![CDATA[Lesmana, Andri]]>;
<![CDATA[Korwa, Daniela Dirgantari]]>;
<![CDATA[Kumala Sari, Ni Putu Winda]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3707
<![CDATA[Dry eye disease (DED) or dry eye disease is a common condition in every country. Dry eyes can cause symptoms such as discomfort or a cycling sensation, red eyes and a feeling of blockage. Inflammation is one of the underlying pathophysiology of dry eyes. One of the therapeutic approaches that has received major attention is the use of omega-3 fatty acid supplements, which are known to have anti-inflammatory properties and can support eye health. Recent studies have shown that omega-3, especially EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), can improve tear quality, improve meibomian gland function, and increase tear production in people with dry eyes. In addition, omega-3 also plays a role in reducing symptoms of dry eyes, although several studies have shown significant results, but the effectiveness of omega-3 in managing dry eyes still requires further research, especially in determining the optimal dose and duration of therapy. This literature review aims to review the latest developments related to the role of omega-3 in dry eye therapy and explore the underlying effects of omega-3 on dry eyes. Further research is expected to provide stronger evidence regarding the role of omega-3 in dry eye therapy.]]>
<![CDATA[Prediktor Mortalitas Pasien Sindrom Koroner Akut di Rumah Sakit X Jakarta Periode September 2023-2024 ]]>
<![CDATA[Rante Tiku, Ristha Monica]]>;
<![CDATA[Arsita, Elli]]>;
<![CDATA[Oktavia, Eva]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3721
<![CDATA[Acute coronary syndrome (ACS) is the leading cause of death from heart disease worldwide. Several studies have identified risk factors that increase mortality among ACS patients, including advanced age, type 2 diabetes mellitus, and chronic kidney disease. This study aims to evaluate the association between these risk factors and mortality in ACS patients at Hospital X Jakarta between September 2023 and September 2024. Contains This study used a retrospective cohort design with analysis of medical record data of patients with ACS. Statistical analysis was performed using chi-squared and Fisher's exact tests to determine the association of age, type 2 diabetes mellitus, and chronic kidney disease with mortality in patients with ACS. Contains A total of 84 patients with a mean age of 59.49 years met the study criteria. The majority of patients had NSTEMI (61.9%) and 56% had type 2 diabetes mellitus. Mortality occurred in 4.8% of the patients. The results of the analysis showed that advanced age (≥60 years) was significantly associated with mortality in SCA patients (p=0.047; RR=4.50). Chronic kidney disease was also significantly associated with mortality (p=0.011; RR=8.16). However, type 2 diabetes mellitus did not show a significant association with mortality (p=0.092). Advanced age and chronic kidney disease were significant predictors of mortality in patients with ACS, whereas type 2 diabetes mellitus was not significantly associated with mortality. ]]>
<![CDATA[Hubungan Pola Makan dengan Penyakit Kanker Kolorektal ]]>
<![CDATA[Mansyur, Firman Riscky]]>;
<![CDATA[Angeline, Reni]]>;
<![CDATA[Christina, Shintia]]>;
<![CDATA[Kertadjaya, Wiwi]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3741
<![CDATA[Cancer is the second leading cause of death globally. Colorectal cancer is one of the most common cancers worldwide. Referring to GLOBOCAN data, in general colorectal cancer is the third highest incidence of cancer after lung cancer and breast cancer. This is attributed to the diet that affects colorectal cancer. Most colorectal cancer are still closely related to genetics. In addition to genetic factors, food intake factors also closely related to colorectal cancer. Current research shows colorectal cancer occurs due to genetic mutations and inflammatory bowel disease. This literature review uses a Literature review design using a search method with a library of research articles or journals through PubMed and other journal sources. The results of the literature review are associated with dietary pattern that affect colorectal cancer, red mead intake is related to the growth of colorectal cancer, while high fiber food can help reduce the risk of colorectal cancer.]]>
<![CDATA[Pengaruh Aktivitas Fisik Terhadap Kecepatan Waktu Reaksi pada Unit Kegiatan Mahasiswa Futsal UKRIDA 2023 ]]>
<![CDATA[Yazmin, Aneta Almira]]>;
<![CDATA[Rumiati, Flora]]>;
<![CDATA[Evan, Evan]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3743
<![CDATA[Reaction time is the duration between an individual receiving a stimulus and the formation of a motor response to that stimulus. One effective method to enhance reaction time is through regular physical activity. Exercise has the potential to increase blood and oxygen flow to skeletal muscles and the brain which can affect a person's reaction time. This study aims to determine the average reaction time before and after physical activity and explore the influence of reaction time on the amount of exercise among respondents. The research adopts a quantitative experimental approach with a one-group pre and post-test design. The total sampling method involves 36 respondents who meet inclusion and exclusion criteria. The findings, analyzed using the Wilcoxon test with p=0.00 (p>0.05), indicate a significant impact of physical activity on the reaction time speed in the student futsal unit of the Faculty of Medicine at Kristen Krida Wacana University in 2023. This research serves as a reference for the community, highlighting the importance of regular physical exercise to improve reaction time. A faster reaction time enables individuals to respond more efficiently and make accurate decisions in a short period during various activities.]]>
<![CDATA[Efektivitas Efektivitas Toilet Seat Sanitizer terhadap Bakteri Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase: Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase ]]>
<![CDATA[Pasaribu, Donna Mesina]]>;
<![CDATA[Gunardi, Wani Devita]]>;
<![CDATA[Andini , Natasya Johanna]]>
<![CDATA[ Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus ]]>
Publisher : <![CDATA[Universitas Kristen Krida Wacana ]]>
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DOI: 10.36452/jmedscientiae.v4i2.3745
<![CDATA[The toilet is one of the facilities provided to meet the needs of users with various backgrounds of different hygiene behavior, so that they can be a source of bacterial transmission, one of which is Escherichia coli (E.coli), which is resistant to producing Extended-Spectrum Beta-Lactamase (ESBL). E.coli producing ESBL can cause infection of various diseases, to overcome this, preventive measures are taken to reduce the level of risk transmission through the use of toilet seat sanitizers. This study aims to determine the effectiveness of toilet seat sanitizer against E.coli producing ESBL. This research is a descriptive observational laboratory study using a toilet seat sanitizer with an active substance of 50%-Benzalkonium Chloride and Ethyl Alcohol 96% against E.coli producing ESBL American Type Culture Collection (ATCC) 35218. The phenol coefficient test was used to measure the effectiveness of the toilet seat sanitizer was compared with phenol, Minimum Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) were tested using the tube method. This study showed that the coefficient of toilet seat sanitizer effective against E.coli producing ESBL was 4,5. MIC active substance toilet seat sanitizer is effective at a concentration of 0,3125%, and MBC at a concentration of 0,625%. The author concludes that the results of the MIC and MBC prove that a toilet seat sanitizer active substances 50%-Benzalkonium Chloride and Ethyl Alcohol 96% is effective as a disinfectant against E.coli producing ESBL ATCC 35218.]]>
