cover
Contact Name
Abd. Kakhar Umar
Contact Email
abdulkaharumar@gmail.com
Phone
-
Journal Mail Official
sciphy@etflin.com
Editorial Address
Sungai Manonda Street, Duyu, Tatanga, Palu City 94225, Indonesia.
Location
Kota palu,
Sulawesi tengah
INDONESIA
Sciences of Phytochemistry
Published by ETFLIN
ISSN : 29625793     EISSN : 2962553X     DOI : https://doi.org/10.58920/sciphy
Sciences of Phytochemistry (SciPhy or Sci Phytochem) is an international, peer-reviewed, open access journal published by ETFLIN. SciPhy aims to offer a widely visible and highly indexed platform for scholars and intellectuals to share their insights and works. From July 2023 onwards, SciPhy will accept only four types of articles: Research, Review, Mini-review, and Opinion. SciPhy accepts research, review, mini-review, and opinion/perspective that falls within the scope of the journal. SciPhy will publish articles that describes new and relevant findings on the following topics: Phytochemical Analysis Techniques: Reviewing advancements in methodologies for identifying and quantifying phytochemicals in plant samples, such as chromatography, spectroscopy, and mass spectrometry. Pharmacological Activities of Plant Compounds: Investigating the biological activities of phytochemicals, including their potential as antioxidants, antimicrobials, anti-inflammatory agents, and anticancer compounds. Natural Product Isolation and Characterization: Detailing the extraction, purification, and structural elucidation of bioactive compounds from plants, fungi, and marine organisms. Bioinformatics and Computational Approaches in Phytochemistry: Exploring computational tools and techniques for analyzing phytochemical data, predicting bioactivities, and identifying potential drug candidates from natural sources. Ethnobotany and Traditional Medicine: Examining the ethnopharmacological uses of plants in traditional medicine systems and their relevance to modern drug discovery and development. Phytochemical Diversity in Plant Families: Studying the chemical composition and variability of secondary metabolites across different plant families and genera. Biological Interactions of Phytochemicals: Investigating the interactions between phytochemicals and biological targets, including enzymes, receptors, and cellular pathways. Phytoremediation and Environmental Applications: Discussing the role of plants in detoxifying pollutants, restoring degraded ecosystems, and contributing to sustainable environmental management. Nutraceuticals and Functional Foods: Highlighting the health-promoting properties of phytochemical-rich foods and their potential as functional ingredients in nutraceutical products. Biotechnological Approaches in Phytochemistry: Reviewing biotechnological methods such as plant tissue culture, genetic engineering, and metabolomics for enhancing the production of valuable phytochemicals or developing novel plant-based products.
Articles 12 Documents
Search results for , issue "Volume 2 Issue 1" : 12 Documents clear
Design and screening of tetracycline antibiotics: an in-silico approach
Sciences of Phytochemistry Volume 2 Issue 1
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphy02010008

Abstract

A prominent class of broad-spectrum antibiotics known as tetracycline works by inhibiting the synthesis of proteins, which prevents the development of bacteria. Tetracycline resistance is typically attributed to one or more of the following causes: ribosomal binding site mutations, acquisition of mobile genetic elements carrying tetracycline-specific resistance genes, and/or chromosomal mutations that increase the expression of intrinsic resistance mechanisms. In this research, our objective is to virtually plan and conduct in-silico experiments to find tetracycline derivatives with inhibitory capability against tetracycline resistance protein. The tetracycline derivatives were screened using the Data Warrior, Discovery Studio, PyRx, and Swiss ADME web tools. Initially, 19 tetracycline derivatives were primarily screened for ADME and toxicity study followed by docking study. Among the tetracycline derivatives, C1, C11, C12, C14, C16, and C17 were found to be the potential drug-like molecules with binding energies of -8.9 kcal/mol, -8.4 kcal/mol, -8.5 kcal/mol, -7.7 kcal/mol, -7.7 kcal/mol, -8.6 kcal/mol respectively. In particular, C1 was predicted to have a better binding affinity towards the target protein than the others.
Comparison of blood glucose control among type 2 diabetics consuming oral antidiabetic drug versus oral antidiabetic drug with home remedies
Sciences of Phytochemistry Volume 2 Issue 1
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphy02010001

Abstract

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