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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "Vol. 1 No. 1 (2019): April" : 6 Documents clear
Evaluation Of Physical Properties Of Liquid Soap Preparations From Virgin Coconut Oil (VCO) And Coconut Oil (CO) Natalino Nunu Pote
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.119

Abstract

Soap is a compound of sodium or potassium and fatty acids from animal oils and vegetable fats which is obtained by the oil hydrolysis process which is then followed by a saponification process under alkaline conditions. Making liquid soap products uses the oil phase, namely virgin coconut oil (VCO) and coconut oil (CO).used as raw material for making surfactants. Surfactants are able to reduce surface tension and interfacial tension by producing foam. The characteristic that influences the quality of liquid soap foam is the fatty acid content. The fatty acid content can affect the physical properties of liquid soap products. The different types of coconut oil used cause the fatty acids contained to be different.Physical properties testing is carried out to find outWhich liquid soap formulation from (VCO) and (CO) formula has the best physical properties.The procedure for making this liquid soap uses the Hot Process method. This method is used because it adapts to the heat- resistant characteristics of coconut oil. The results of the research showed that liquid soap preparations from (VCO) and (CO) were evaluated for their physical properties in terms of organoleptic and stability parameters such as foam height test, pH test, homogeneity test, viscosity test and specific gravity test, which obtained a significant value of <0.05. meaning they both have good physical characteristics. As well as respondents' acceptance of the physical properties of liquid soap preparations from (VCO) and (CO) where the results show that respondents have the same satisfaction regarding the quality of liquid soap.
Analysis of Family Support and Levels of Depression HIV/AIDS Patients in Adherence of Antiretroviral Medication in Kediri City Hanie Kusuma Wardan
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.120

Abstract

Antiretroviral (ARV) medication adherence is important because ARV can improve quality of live in HIV/AIDS’ patients. Adherence to ARV medication influenced many factors, including family support and levels of depression experienced by patients of HIV/AIDS. The purpose of this research is to analyze the effect of family support and levels of depression patients HIV/AIDS against the ARV medication adherence in Kediri. Research’s design is quantitative research using the approach of cross sectional. The sampling technique used is proportional sampling with cluster random samples as much as 133 respondents who get ARV therapy in Gambiran Hospital, “Pesantren 1” Primary Health Centre, and Seroja Clinic. Data analysis techniques using logistic regression test. The results show that 133 of the respondents, 98 respondents (73.7%) get family support and adherence taking ARV medication, and 99 respondents (74.4%) are not depressed and adherence taking ARV medication. Adherence in this research is referred to take ARV by dosage and by time exactly in schedule. The results of the analysis using logistic regression test shows the value significance of 0.000 < (α = 0.05), meaning that H0 is rejected and the H1 is accepted, this means that there is a relationship of family support and levels of depression HIV/AIDS’ patients against the ARV medication adherence. Family Support and levels of depression HIV/AIDS’ patients affect the ARV medication adherence 80.2%. Conclusion, to get adherence in ARV treatment, HIV’s patient needs family support and get not in depression condition.
Variations in Aerosil concentration in Chlorpeniramin Maleat (CTM) capsule preparations on test results Melinda Putri
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.121

Abstract

Capsules are solid preparations consisting of a drug in a hard or soft shell that can dissolve. (Fatmawaty, et al. 2012). Hard capsules are usually made from gelatin which consists of the capsule shell, the body and the capsule cap. The two parts of the capsule cover will cover each other when brought together and the cover will cover the body of the capsule (Ansel, 2005). Chlorpeniramin Maleat CTM) is used as an antihistamine. Antihistaminics are drugs that oppose the action of histamine on H-1 histamine receptors so they are useful in suppressing allergies caused by the appearance of symptoms due to histamine (Ansel, 1989). Antihistamines work by occupying the place in cells normally occupied by histamine, thereby eliminating histamine's ability to cause allergic reactions (Harkness, 1989). Adsorbents are substances that trap other components such as water. Aerosil is an adsorbent that is widely used in capsule preparations. Apart from having a large water absorption capability and capacity of around 50%, if dried, Aerosil will not reduce the existing water content (Lachman, 1989). The active ingredient used is CTM, where this material is hygroscopic, meaning it is able to absorb water molecules from its environment, so adsorbents are added to prevent moisture from the preparation during storage. Based on the description above, this formulation was made by varying the aerosil concentration, namely 5% (F1); 7% (F2); and 9% (F3) which is intended to observe the ability of the adsorbent as seen from hygroscopic testing of the preparation during storage. The results of this research is disintegration time on our formulations resulted in formulation 1 starting to disintegrate within 01:03 until it was completely dissolved, taking 12:02. formulation 2 started to break down within 01:40 and until everything dissolved with a duration of 12:02. The 3rd formulation started to break down within 02:05 with the total duration until it was completely dissolved was 12:58. These three formulations are in accordance with the FI standard, namely less than 30 minutes.
EFFECTIVENESS OF PHARMACIST COUNSELING ON ADHERENCE TO ANTIHYPERTENSIVE THERAPY OF HYPERTENSION PATIENTS IN PUSKESMAS NGLETIH Indah Yuli Antika
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.122

Abstract

Hypertension or high blood pressure is an increase in systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥90 mmHg in two measurements with an interval of five minutes in a state of rest/quiet. The use of antihypertensive drugs must always be monitored because long-term use of drugs will affect adherence to taking medication and cause further complications or disease severity. Counseling provided by pharmacists is one of the efforts to educate and monitor patient treatment to increase patient compliance in undergoing treatment.
Formulation and Determination of Sun Protection Factor (SPF) of Sunscreen Gel Preparations Containing Epigallocatechin Gallate (EGCG) Using the Spectrophotometric Method Oppy aesaiw
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.123

Abstract

Long-term exposure to the sun causes various kinds of abnormalities in human skin so it requires skin protection from the outside. Sunscreen is a cosmetic therapy that can shield the skin and face against UV radiation, including the potential to induce accelerated ageing, sunburn, and skin cancer. Tea leaf-derived polyphenol compounds, particularly EGCG, have the most potent and plentiful antioxidant action. The objective of this work is to investigate the impact of variations in epigallocatechin gallate (EGCG) levels on the physical properties and effectiveness of sunscreen gel. This study used an experimental design with four EGCG gel formulas (negative control (0%), F1 (0.1%), F2 (0.2%), F3 (0.4%)) and tested with a UV-Vis spectrophotometer with the resulting absorbance calculated using the Mansur formula.The results showed that the SPF value increased with increasing EGCG concentrations (negative control, F1, F2, F3, positive control: 18.94 (moderate), 22.55 (moderate), 29.10 (moderate), 41.58 (high), 48.11 (high)). The highest SPF value on Formulation 3 indicates a high level of sunscreen capability. EGCG gel with a concentration of 0.4% has good physical characteristics (slightly thick texture, odorless, transparent white color, homogeneous, pH 6.57, adhesion 3.30, diffusion 6.36) and the highest SPF value (41.58). The statistical test using Kruskall-Wallis followed by the Man-Whitney test showed a significant difference in a p-value of 0.05.
IN SILICO STUDY OF THE POTENTIAL OF GAMBIR LEAF CATECIN COMPOUNDS (Camellia sinensis L.) AS ANTI-BACTERIAL AGAINST Mycobacterium tuberculosis IN InHA Riska Luthfiani
Strada Journal of Pharmacy Vol. 1 No. 1 (2019): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v1i1.154

Abstract

Isoniazid is an anti-tuberculosis pro-drug by inhibiting mycolic acid in bacterial cell walls which requires activation by inhA and the presence of mutations in the Kat-G gene increases resistance to isoniazid. The disadvantages is that high humidity can cause bacteria to grow quickly. Pathogenic bacteria are one of the causes of infection, both gram-positive bacteria and gram-negative bacteria. One of the diseases caused by bacteria is tuberculosis, which is caused by Mycobacterium tuberculosis. The four compounds of the catechin group from gambir plants, namely Epikatekin (EC), Epigallo catechin (EGC), Epikatekin gallate (ECG), and Epigallokatekin gallate (EGCG), three of which meet the criteria of Lipinski's five laws, namely in EC, ECG and EGC with one violation, namely Hydrogen Bond Donor> 5 where Lipinski's criteria for compounds are said to be good if HBD < 5

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