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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 77 Documents
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Husband's Support for Adherence of Pregnant Women Consuming Iron Folic Acid Hanie Kusuma Wardani
Strada Journal of Pharmacy Vol. 4 No. 1 (2022): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i1.45

Abstract

Stunting is a global problem, including in Indonesia. UNICEF reports the incidence of stunting in Indonesia that in 2018, almost 3 in 10 children under five years of age were stunted or too short for their age, while 1 in 10 was underweight or too thin for their age. Various efforts to prevent stunting have been carried out by the Indonesian government, one of them is iron supplementation for pregnant women. The success of this program is largely determined by the adherence of pregnant women in consuming iron supplement that they receive. This study aims to determine the effect of husband's support on the adherence of pregnant women in consuming iron supplements. This research is a literature study by reviewing 15 journals related to the influence of husband's support on the adherence of pregnant women in consuming iron supplements. The type of data used is secondary data. The method of data collection is literature study. The method that will be used for the assessment is a literature study. The data obtained were compiled, analyzed, and concluded so as to obtain conclusions regarding the study of literature. Total of 15 articles were reviewed, all of which were written from 2015 – 2021. All articles concluded that there was a significant relationship between husband's support for pregnant women's adherence to iron supplements. Conclusion: Based on previous research, it can be concluded that husband's support increases the adherence of pregnant women in consuming iron supplements.
Antibacterial Activity Test and Wound Healing Infection Telang Leaf Extract (Clitoria ternatea L.) in Hyperglycemic Rabbits Arif Wijayanto; Juvita Herdianty; Adjie Wahyu Pradana
Strada Journal of Pharmacy Vol. 4 No. 1 (2022): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i1.46

Abstract

This study was conducted to determine the antibacterial activity and wound healing of Telang (Clitoria ternatea L.) leaf extract against Staphylococcus aureus ATCC 25293 and Escherichia coli ATCC 25922 in 15 New Zealand rabbits aged 3-5 months weighing 1500–2500 grams of hyperglycemia induced by alloxan and randomly divided into 5 groups, namely normal, negative control (cream base), positive control (Sagestam® which each gram contains Gentamycin Sulfate equivalent to 1 mg of Gentamycin), topical administration of 10% and 20% Telang leaf extract cream. The back skin of the hyperglycemic rabbit was injured with a punch biopsy with a diameter of 5 mm, a depth of ± 0.5 mm, then treated according to the test group for 14 days. Parameters measured included wound diameter and histological observations of infected and non-infected wounds in hyperglycemic rabbits. The results showed that 10% Telang leaf extract cream had antibacterial activity against S. aureus and E. coli which was comparable to the positive control, namely the diameter of the inhibition zone against S. aureus and E. coli was 27.3mm and 18.5mm. Telang leaf extract cream also had infection wound healing activity which was comparable to positive control in hyperglycemic rabbits, wound healing activity for infected wounds was 0.9 mm and non-infected wounds were 0.8 mm.
Test Antibacterial Activity from Ashitaba Stem Ethanol Extract (Angelica keiskei (Miq.) Koidz) Against Streptococcus mutans ATCC 25175 Luluk Aniqoh Meliana Putri
Strada Journal of Pharmacy Vol. 4 No. 1 (2022): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i1.47

Abstract

Ashitaba stems contain chemical compounds such as alkaloids, tannins, flavonoids and saponins. This study aimed to determine the antibacterial activity of ashitaba stem extract against Streptococcus mutans ATCC 25175. Ashitaba stem powder was extracted by maceration method with 96% ethanol solvent. The extract obtained was tested for antibacterial activity against Streptococcus mutans ATCC 25175 using the diffusion method with concentrations of 50%, 25%, 12.5% ​​and 6.25% to determine the concentration of the most active extract. The most active extract was known from the diameter of the inhibition zone which had the greatest value. The results showed that the ashitaba stem extract had antibacterial activity against Streptococcus mutans ATCC 25175. The 50% concentration of the ashitaba stem extract had an average inhibitory diameter of 18 mm which was the most active concentration of the ashitaba stem extract, the 25% concentration of the ashitaba stem extract had an average The average inhibitory diameter was 16.5 mm, the concentration of 12.5% ​​of the ashitaba stem extract had an average inhibitory diameter of 14.8 mm, the concentration of 6.25% of the ashitaba stem extract had an average inhibitory diameter of 12.5 mm.
Analysis of free Fatty Acid Levels (as Lauric Acid) Pure Coconut Oil (Virgin Coconut Oil / VCO) for sale in Kediri City Sri Rahayu Dwi Purnaningtyas
Strada Journal of Pharmacy Vol. 4 No. 1 (2022): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i1.48

Abstract

Pure Coconut Oil (Virgin Coconut Oil / VCO) is a vegetable oil that contains medium chain saturated fatty acids. The medium-chain saturated fatty acid that has the highest content in virgin coconut oil is lauric acid. Lauric acid can be directly absorbed by the liver and used as an energy source. This study aims to determine the levels of free fatty acids (as lauric acid) in virgin coconut oil (Virgin Coconut Oil/VCO) according to SNI Standard 7381: 2008. The samples used in this study were pure coconut oil from various brands on the market in Indonesia. Kediri city. This study used an alkalimetry method to identify the free fatty acid levels in the sample. From the results of the analysis on 5 (five) brands of virgin coconut oil, it was found that all samples met the requirements of SNI 7381: 2008 which is a maximum of 0.2%. The results of the analysis of the levels of free fatty acids as lauric acid, the smallest 0.1643% and the largest 0.1988% according to the requirements of SNI.
Sunscreen Activity of Soursop Seeds Extract Erlien Dwi Cahyani; Antonius Budiawan; Levi Puradewa
Strada Journal of Pharmacy Vol. 4 No. 1 (2022): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i1.49

Abstract

Indonesia is a tropical climate country that is rich in sunlight. Sunlight overexposure leads to skin damage such as sunburn, black spots, wrinkles, and aging skin which is caused by oxidative stress. Soursop is a fruit rich in flavonoids that has the antioxidant activity to prevent oxidative stress and is known for its sunscreen effect. This study was aimed to determine the sunscreen activity of soursop seed extract by Sun Protective Factor (SPF) parameter. Soursop extract divided to 0.15 and 0.25% concentration and the SPF value was measured quantitatively using Spectrophotometer UV-Vis. SPF measurement result showed that soursop seeds extract 0.15 and 0.25% concentration gives 4.35 and 7.38 respectively SPF value. Soursop seeds extract showed sunscreen activity with low protection category.
ANTIBACTERIAL ACTIVITY TEST OF KETAPANG LEAF ETHANOL EXTRACT (Terminalia catappa L,) AND GARLIC TUBER (Allium sativum L,) AGAINST Pseudomonas aeruginosa ATCC 27853 Ivan Julianus Mesak
Strada Journal of Pharmacy Vol. 4 No. 1 (2022): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i1.62

Abstract

Pseudomonas aeruginosaare bacteria that are widely distributed in nature. These bacteria cause several infectious diseases, namely dermatitis, otitis externa, folliculitis, eye infections, and infections of burns, as well as of the respiratory tract. Clinical treatment so far is long term and carries the risk of developing bacterial resistance to antibiotics. The purpose of this study was to determine the ability of the antibacterial activity of the ethanol extract of ketapang leaves (Terminalia catappa L.) garlic (Allium sativum L.),The purpose of this study was to determine the single dose and combination of ethanol extract of ketapang leaves (Terminalia catappa L.) and garlic (Allium sativum L.) which have effective bacterial activity againstPseudomonas aeruginosa ATCC 27853 and the values of the Minimum Inhibitory Concentration (MIC) and Minimum Killing Concentration from the ethanol extract of ketapang leaves (Terminalia catappa L.) and garlic (Allium sativum L.). Alilicin compound in garlic, the tannin and flavonoid compounds in the ketapang plant act as antibacterial compounds. This research is an experimental research using diffusion and dilution methods. Garlic extract and ketapang leaf extract were obtained by maceration method extraction using 96% ethanol solvent for 5 days. The extract concentrations obtained were 100%, 50%, 25%, 12.5%, 6.25%, 3.125%, 1.563%, 0.781%, 0.391%, 0.196%. The data obtained were then analyzed based on bacterial growth Pseudomonas aeruginosa ATCC 27853 was tested in a test tube and selectively mediated by the dilution method by determining the Minimum Inhibitory Concentration (MIC) based on observations in the test tube where the smallest concentration of the test material in the tube showed that the culture results were starting to become clear (no bacterial growth) and the Minimum Kill Concentration. ). Was determined based on the results of observations of the test material and the smallest concentration of the test material on PSA media which was indicated by the absence of colony growth on solid media. The test results showed that the ethanol extract of Ketapang leaves (Terminalia catappa L.) and garlic bulbs (Allium sativum L.) singleand the combination of both have antibacterial activity against Pseudomonas aeruginosa ATCC 2785. The combination of ethanol extract of ketapang leaves and garlic bulbs at a concentration of 50%:50% was the most effective extract as an antibacterial against Pseudomonas aeruginosa ATCC 27853, Minimum Kill Concentration (KBM) ethanol extract of ketapang leaves and garlic bulbs against Pseudomonas aeruginosa ATCC 27853 is 50%.
The Effect of Solvent Variation on Flavonoid Content of Purslane Herb (Portulaca grandiflora Hook.) Indriasari, Christina
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.64

Abstract

Purslane is from the Portulaceae family which contains active phenolic compounds and has different antioxidant activities. Portulaca grandiflora Hook. is one of the species of purslane where all parts of the plant are useful. Purslane herb (Portulaca grandiflora Hook.) contains active compounds of alkaloids, flavonoids, tannins, terpenoids, and saponins. Flavonoids act as antioxidants. This study aims to determine the differences in flavonoid levels of extracts resulting from soxhletation of purslane (Portulaca grandiflora) herb with different solvents. This research is an experimental study with soxhletation extraction process and assay using a UV-Vis spectrophotometer with various concentrations of 5, 10, 15, 20, 25, and 30 ppm at a wavelength of 424.5nm. The flavonoid content in each extract of n-hexane, ethyl acetate, and 96% ethanol was 17.91% w/w; 23.27% w/w; 11.67% w/w.
Lip Cream Formulation With Natural Dyes From Secang Wood Leather Luluk Aniqoh Meliana; Juvita Herdianty; Arif Wijayanto
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.65

Abstract

Colorants are an important part of decorative cosmetics, including in lip cream preparations. Secang bark (Caesalpinia Sappan) contains chemical compounds of flavonoids, polyphenols, tannins and essential oils. Researchers formulate lip cream preparations by utilizing natural pigments contained in the bark of secang wood. The preparations were made with various concentrations of sappan bark extract, namely 15%, 20%, and 25%. Evaluation of the preparations made is an evaluation of physical quality including organoleptic tests, homogeneity, pH, spreadability, adhesion, smearing power, photostability, and stability tests by centrifugation method. Evaluation of safety was carried out through irritation test with patch test method and preference test. The results of the evaluation of lip cream preparations showed that all formulas had good greasing power and homogeneity, were physically stable which was characterized by no separation, and had good dispersibility, spreadability, and stable pH value. All preparations during storage for 21 days did not show changes in texture and odor. Then in terms of color, both organoleptically and photostability testing did not show a decrease in color intensity. Based on respondents' responses, the most preferred formula is formula II with the addition of an extract of 20%.
Antibacterial Test of Liquid Soap Preparations Rambutan Peel Extract (Nephelium lappaceum Linn) the Growth of Staphylococcus Aureus Juvita Herdianty; Luluk Aniqoh Meliana Putri; Arif Wijayanto
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.66

Abstract

Long-term use of antibiotics leads to resistance. Rambutan fruit is a fruit which grows seasonally, but the utilization of the fruit skin is still lacking. Several studies have been carried out but limited to the flesh and leaves. The purpose of this study was to utilize rambutan peel waste into a liquid soap preparation and then carry out an antibacterial test against Staphylococcus aureus bacteria. The content of compounds from the skin of rambutan fruit (Nephelium lappaceium Linn) is thought to have antibacterial properties. The content test was carried out using a phytochemical screening method. The screening results of rambutan peel extract showed the presence of alkaloids, flavonoids, saponins, and tannins. The antibacterial test method used the well diffusion method with concentrations of 20% 40%, 60% positive control of Biore liquid soap and negative control of soap base. The test parameters for liquid soap preparations include: organoleptic test, homogeneity test, pH test, foam height. The results showed the best concentration of 60% had the ability as an antibacterial against Staphylococcus aureus.
Test The Wound Healing Activity Of Nephelium Lappaceium Fructus Cortex Extract Ointment On New Zealand Rabbits Arif Wijayanto; Luluk Aniqoh Meliana Putri; Juvita Herdianty
Strada Journal of Pharmacy Vol. 4 No. 2 (2022): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v4i2.67

Abstract

Nephelium lappaceium Linn.(Rambutan) is a natural ingredient rich in active substances that are beneficial to human health. In this study, the use of Nephelium lappaceium fructus cortex was used for the healing of open wounds where Nephelium lappaceium fructus cortex contains tannins which are expected to help heal open wounds. The content test was carried out using the phytochemical screening method of Nephelium lappaceium fructus cortex extract which showed the presence of alkaloids, flavonoids, saponins, and tannins, then a wound healing test was carried out with Nephelium lappaceium fructus cortex extract which was divided into 5 groups randomly, namely normal, negative control (Vaseline album) , positive control (Betadine salp® each gram contains 10% Povidone Iodine), presented topically 7.5% and 15% Nephelium lappaceium fructus cortex extract ointment. The back skin of New Zealand rabbits is 3-5 months old, weighs 1500–2000grams, has normal and healthy activities and has agile activities, is normal and in healthy condition, then was injured with a punch biopsy with a diameter of 5 mm, a depth of ± 0.5 mm, then treatment according to the test group for 21 days. Parameters measured included wound diameter in rabbits. The results showed that the ointment extract of Nephelium lappaceium fructus cortex 15% had an open wound healing activity which was comparable to a positive control with an open wound healing activity of 0.2mm.

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