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Juvita Herdianty
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INDONESIA
Strada Journal of Pharmacy
Published by Universitas Strada Indonesia
ISSN : 27763544     EISSN : 27979180     DOI : https://doi.org/10.30994/sjp
Core Subject : Health, Science,
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology
The journal includes various fields of pharmaceuticals sciences such as: Pharmacology and Toxicology; Pharmacokinetics; Community and Clinical Pharmacy; Pharmaceutical Chemistry; Pharmaceutical Biology; Pharmaceutics; Pharmaceutical Technology; Biopharmaceutics; Pharmaceutical Microbiology and Biotechnology; Alternative Medicines;
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Ilmu Farmasi
Articles 6 Documents
 1 
Search results for , issue "Vol. 6 No. 1 (2024): April" : 6 Documents clear
Description Of The Usage Of Antiretroviral Medicine With Atc/Ddd Method In The Primary Health Care Centers Of Kediri 2021 Dandi Fathor Rozy Pradana Saputra; Chinthia Devientasari
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.109

Abstract

AIDS (Acquired Immune Deficiency Syndrome) is a collection of symptoms and infections caused by damage to the human immune system, HIV (Human Immunodeficiency Virus ), a virus that can weaken human immunity. PLWHA patients must undergo antiretroviral virus (ARV) drug therapy, one of the drug use analysis classification systems is using the ATC/DDD system which is a means of researching drug use in an effort to improve the quality of drug use, one of these components is the presentation and comparison of drug consumption levels. international. The aim of this research is to determine the use of antiretroviral drug consumption in primary health care center in the Kediri City area for the 2021 period using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) method. The design of this research is quantitative descriptive, namely describing a particular event systematically and accurately and the treatment of this research is the process of collecting data and evaluating the use of antiretroviral drugs as well as verifying Primary health care center data by interviewing primary health care center pharmacists in the Kediri city area in 2021. Consumption of antiretroviral drugs (ARVs). ) is highest in the Campurejo primary health care center, namely Lamivudine (3TC) as much as 31.71%, Balowerti in primary health care center with Zidovudine (AZT) as much as 29.02% and Pesantren 1 primary health care center with the drug Nevirapine (NVP) as much as 32.62%, while the use of ARV drugs is low. At the Campurejo primary health care center, it was 0.0002% of the drug Dolutegravir (DTG), and at the Balowerti primary health care center, it was 0.0012% of the drug Dolutegravir (DTG), then at Pesantren 1 primary health care center , it was 0.0015% of the drug Dolutegravir (DTG). The incidence of HIV is still high in Indonesia, especially in the city of Kediri.
Testing The Effectiveness Of Burns Healing Of Gel Preparations Jatropagar ( Jatropha Curcas L) Leaf Extract On Male White Rats ( Rattus Norvegicus) Angelina Tamo Inya; Ivan Junius Mesak
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.110

Abstract

Indonesia has a variety of traditional medicinal plants for treating burns. One of them is Jatropha leaves which contain active substances such as saponins, tannins, alkaloids and flavonoids which have antibacterial, antioxidant, anticancer and anti-inflammatory properties. The aim of this research was to determine the effectiveness of Jatropha leaf preparations with extract concentrations of 10%, 15%, 20% on healing burns. This research stage includes plant determination, simplicia making, extract making, phytochemical screening testing, physical quality testing of gel preparations and animal testing. The research was experimental by comparing the effectiveness of healing burns in grouped mice and Jatropha leaf extract gel preparations and the most effective formula for healing burn wounds was Jatropha leaf extract gel preparations at concentrations of 10%, 15%, 20%. Statistical test results showed that there was a difference in the duration of healing of burn wounds in male white rats between Jatropha curcas (Jatropha curcas L) leaf gel preparations with concentrations of 10%, 15%, 20%, bioplaceton gel and gel base.
Rationality of Prescribing Diabetes Mellitus Drugs Using Beers Criteria for Geriatric Patients in Outpatient Installations dr. Iskak Hospital Kuni Rofi'aty; Hanie Kusuma Wardani
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.117

Abstract

Diabetes mellitus (DM) is se group of metabolic disorders with symptom hyperglycemia Which happen caused because abnormality secretion insulin and insulin action or both . Diabetes mellitus (DM) is a global problem in which 20% of sufferers are geriatrics. Treatment of DM in geriatrics has the potential to occur irrationally due to the complexity of health problems in geriatrics. Irrational prescribing has a negative impact on health care facilities, patients, and society. One method of assessing rational prescribing is the Beers criteria, developed by the American Geriatrics Society Beers Criteria 2 019. The purpose of this study was to determine the rationality of prescribing DM drugs using the Beers criteria for geriatric patients at the outpatient installation at RSUD dr. Iskak Tulungagung. This research is a descriptive observational study with a cross sectional design. Retrospective data collection on 275 medical record documents of geriatric patients with a diagnosis of DM at the outpatient installation of RSUD dr. Iskak – Tulungagung in the 2021 period. Samples were analyzed using the American Geriatrics Society Beers Criteria 2019 guidelines . The results of the study DM drugs in the Sulfonylurea class were most widely used (13.1%) and 41,3 % identified potentially inappropriate medications (PIMs). The use of potentially inappropriate drugs is 7,32 %, the use of drugs that interact with disease is 3,8%, the drugs that must be used with caution, 6,4%, the drugs that have the potential to interact clinically 0,3%, and the use of drugs that must be avoided or reduced dose related to renal function 0,3%.
Development of a Wireless Communication Enabled Device for Monitoring Heart Rate and Body Temperature for Independent Use La Febry Andira Rose Cynthia; Alvin Hetriawan; Fatkhur Rokhman; Muhammad Faris Pradana; Lailis Syafa’ah
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.118

Abstract

Human health conditions can be seen from their heart rate and body temperature. Research aims to make it easier for health workers and humans in general to know their heart rate and body temperature. Therefore, a portable heart rate monitoring device was designed that uses an IoT system. The portable design aims to make the tool practical, and the use of IoT makes it easier for health workers to see patient conditions remotely. The MAX30100 sensor is used to determine heart rate while the DS18B20 sensor is used to determine body temperature which is connected to the microcontroller. It is hoped that this research will make it easier for health workers and humans to receive immediate treatment during emergencies.
Analysis of Salicylic Acid in Biological Fluids (Serosal) Using Uv-Vis Spectrophotometry Chintia D; Resca S.S.; Anggra I.N.A
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.163

Abstract

Pharmacokinetics is an aspect of pharmacology that covers the fate of drugs in the body, namely absorption, distribution, metabolism, and excretion (ADME). Overall, bioavailability shows the kinetics and comparison of the levels of active substances that reach the bloodstream to the amount of drug given. Method validation is carried out to determine that the analytical method used is accurate, specific, reproducible, and resistant to the analyte to be analyzed. An analysis model must be validated to verify that its performance parameters are sufficient to overcome the analysis problem. The research method used is included in observational experimental research. Observational experimental research is research conducted by analyzing a compound and testing it. The results of this study obtained a standard curve value of Y = 0.006x + 3.401, r2 = 0.334 with λmax 329 nm. Recovery (% recovery) in the study, the average recovery value of the concentration was 200μg/mL (118.8%); 150 μg/mL (72.1%); 100 μg/mL (131.5%). Systemic error of series concentration 200 μg/mL (-18.8%); 150 μg/mL (278%); 100 μg/mL (-31.5%). Based on the study, validation testing of the method with further precision and accuracy is needed.
Formulation of Acetaminophen Granules with Porang Tuber Amylum (Amorphophallusoncophyllus) that Meets the Parameters of Particle Size Distribution and Destruction Time Arif Wijayanto; Juvita Herdianty
Strada Journal of Pharmacy Vol. 6 No. 1 (2024): April
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v6i1.168

Abstract

Many farmers are interested in planting porang tubers, with many farmers planting porang tubers, the price of porang tubers will decrease during harvest . Porang tubers have several contents, namely starch, glucomannan, fiber, fat, protein, minerals and vitamins. Glucomannan content can be used as a tablet binder, thickener, gilling agent, film former, coating material emulsifier, and stabilizer. The purpose of this study was to determine the concentration of porang tuber flour as a binder in Acetaminophenum granules using the wet granulation method. Granules were made into three formulations with variations in the concentration of porang tuber flour, namely FI 5%, FII 7.5% and FIII 10%. GRANULES were tested for tablet uniformity, tablet hardness, tablet fragility , disintegration time, and granule size distribution. The data obtained were analyzed using Kruskal Wallis. The results of the analysis showed that variations in the concentration of porang tuber flour had different effects, based on the Kruskal Wallis analysis which showed a significant value of 0.10 (p> 0.05). The formulation that has a good physical quality test is formulation III, with a tablet hardness value of 6.84 kg and a disintegration time of 5.74 minutes which is almost close to the control (+) 14.27 kg and 6.38 minutes. The higher the concentration of porang tuber flour , the higher, the longer the disintegration time.

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