Multidisciplinary Journal of Akseprin Indonesia
The Multidisciplinary Journal of Akseprin Indonesia (MJAI) is a scientific journal dedicated to publishing research results, case studies, work reports and literature reviews that are interdisciplinary and multidisciplinary in nature from various major disciplines. The journal aims to bridge the gap between sciences, promote collaboration, and present comprehensive solutions to complex challenges. The scope of MJAI includes studies from the main groups of sciences which, including: Engineering ,Physical and Chemical Science : Engineering and Technology, Material Science, Statistics, Chemical Engineering, Chemistry, Computer Science, Information Technology, Earth and Planetary Science, Energy, Mathematics, Physics and Astronomy, Mathematics Life Sciences : Agricultural, Biological Sciences, Biotechnology, Arachnology, Biodiversity and Conservation, Entomology, Limnology, Ichthyology, Malacology, Immunology and Microbiology, Neuroscience, Biochemistry, Genetics, Molecular Biology, Environmental Science, Ecology, Marine Biology. Health & Medical Science : Medicine and Dentistry, Nursing, Health Professions, Pharmacology, Toxicology, Pharmaceutical Science, Veterinary Science, Veterinary Medicine, Health Care, Medical Education. Social Science and Humanities: Arts and Humanities, Business Management, Hotel Management, Management, Economics, Law, Finance, Psychology, Political Science Tourism, Accounting, Decision Science, Education, , Physical Education, English Literature, Social Work and History., Sociology, Corporate Governance.
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<![CDATA[Ethosomes serve as a non-invasive drug delivery system capable of penetrating the skin, merging with cell membrane lipids, and releasing pharmaceuticals ]]>
<![CDATA[Bhavana Radhika Hemanth]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
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<![CDATA[The skin is one of the largest and most accessible organs in the human body, and its application as a pathway for drug delivery presents several advantages compared to conventional drug delivery systems. These benefits encompass reduced variability in plasma medication concentrations, prevention of gastrointestinal complications and first-pass metabolism, along with enhanced patient adherence. Transdermal drug delivery systems (TDDS) are characterised as self-contained, discrete dosage forms that, upon application to undamaged skin, administer medications at a controlled rate to the systemic circulation. Ethosomes are innovative lipid carriers consisting of ethanol, phospholipids, and water. These ethosomes are engineered as a non-invasive drug delivery method capable of penetrating the skin, merging with cell membrane lipids, and releasing the drug. Ethosomes can be prepared by either thermal or non-thermal processes. Evaluation criteria for ethosomes encompass dimensions, morphology, drug concentration, and zeta potential. Ethosomes have been effectively assessed for the administration of multiple pharmaceuticals, including cyclosporine, insulin, and salbutamol. Ethosomes possess significant potential as a crucial medication delivery mechanism in the future]]>
<![CDATA[To evaluate the prevalence of digital burnout among medical science students and correlate the levels of digital burnout with other demographic variables ]]>
<![CDATA[Nisha Shainy Daud]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
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<![CDATA[Background: Frequent use and exposure to digital devices in both academic and personal settings predisposes university students to digital burnout. Objective: To evaluate the incidence of digital burnout among medical science students and to associate the levels of digital burnout with diverse demographic characteristics. Methods: A descriptive cross-sectional study was done using convenient sampling among 300 students (86.3% male, 13.7% female) across various programmes and academic levels. The instruments employed for data collection were Tool 1 - Demographic Data and Tool 2 - Digital Burnout Scale (DBS). Findings: The findings indicated that 75% of the students experienced moderate to mild burnout. In general, and across all subcategories, average ratings reflect moderate levels of burnout. A notable disparity in digital burnout was identified among age groups (F=4.62, p=0.011), with individuals aged 24 and above exhibiting the highest levels of burnout relative to their younger peers. A statistically significant difference was observed in digital burnout scores among groups categorised by online duration, specifically beyond 6 hours (F = 4.52; p = 0.007). The study reveals that students experience moderate burnout, correlated with age and duration of gadget usage. Conclusion: Specific strategies are necessary to mitigate digital burnout, particularly among seniors and individuals who engage extensively with online platforms. Institutions must thoroughly investigate the implementation of programs to foster better digital habits and offer resources that enhance students' well-being in progressive digital academic settings]]>
<![CDATA[Assessment of Saponification, Acid, Peroxide, and Iodine Values by Physicochemical Analysis of Reused Cooking Oil ]]>
<![CDATA[Lie huan zang]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
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<![CDATA[This study examines the deterioration of frying oils utilised in local food enterprises by analysing essential quality indicators. Oil samples, obtained after extended frying of typical food items like samosas, Manchurian, chicken, medu vada, jalebi, and momos for durations of 8 to 9 hours, were analysed. Palm and vegetable oils were evaluated for acid value, saponification value, peroxide value, and iodine value utilising standard titrimetric methods. Acid-base titration techniques were employed to determine acid, peroxide, and saponification levels, whereas iodometric titration was utilised for assessing iodine value. The comparative analysis underscores the chemical alterations in reused oils, stressing the importance of consistent monitoring to guarantee safety and appropriateness for ongoing usage in food preparation]]>
<![CDATA[Pharmaceutical Industry Driven by Artificial Intelligence and Machine Learning ]]>
<![CDATA[Sandha Udhan Baorhide]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
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<![CDATA[Artificial Intelligence (AI) and Machine Learning (ML) are transforming the pharmaceutical industry at all phases—drug research, development, regulatory compliance, quality assurance, and post-marketing monitoring. These technologies enhance data processing, precision, and timeliness through the utilisation of intricate algorithms and extensive healthcare datasets. Artificial intelligence aids in drug target identification, drug design, toxicity prediction, and pharmacokinetics modelling, while also enhancing regulatory processes and pharmacovigilance. Despite its advantages, difficulties persist, including data privacy, algorithmic bias, explainability, and accountability. Regulatory frameworks and ethical considerations must evolve to ensure the safe and equitable application of AI in pharmaceuticals. This article examines the current applications, benefits, hazards, and future potential of AI and ML in revolutionising medication development and healthcare outcomes.]]>
<![CDATA[A Comparative Analysis of the Efficacy of Mulligan Bent Leg Raising Versus Slump Stretching Combined with SWD in Mechanical Low Back Pain ]]>
<![CDATA[Okkagani Berranghi Obuun]]>
<![CDATA[ Multidisciplinary Journal of Akseprin Indonesia Vol. 3 No. 1 (2025): January-April ]]>
Publisher : <![CDATA[AKADEMI SERTIFIKASI PROFESI INTERNASIONAL ]]>
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<![CDATA[The problem statement: Low back pain (LBP) is the most prevalent, self-reported form of musculoskeletal pain, frequently recurrent, and carries significant socio-economic implications. Approximately eighty percent of low back pain is attributed to "mechanical back pain," resulting from muscle strain or ligament tear in the back. The muscular strain and ligament sprain result from abrupt, unfamiliar exercises and incorrect posture. Methodology: The participants were recruited through Sri Venkateshwaraa Medical College Hospital and Research Centre, Ariyur, Pondicherry-605 102. The objective of the study was to evaluate the efficacy of Mulligan Bent Leg Raising (MBLR) compared to Slump Stretching combined with SWD in alleviating pain and enhancing Straight Leg Raise (SLR) in cases with mechanical low back pain. Outcomes: The statistical analysis derived from the unpaired t-test indicates that the post-test values for range of motion and pain in Group A and Group B are 5.39 (p < 0.001) and 5.43 (p < 0.001), respectively. The statistical study revealed a considerable difference between Group A and Group B, with Group A demonstrating more effectiveness. The study concluded that the Mulligan bent leg raise, in conjunction with SWD, was beneficial in treating mechanical low back pain in college students]]>
