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Contact Name
Asmat Burhan
Contact Email
asmatburhan1@gmail.com
Phone
+6285746157782
Journal Mail Official
indahnoni138@gmail.com
Editorial Address
Alana Crown Blok B16, Samparangin, Teluk, Purwokerto Selatan, Banyumas.
Location
Kab. banyumas,
Jawa tengah
INDONESIA
Journal of Wound Research and Technology
ISSN : -     EISSN : 30380043     DOI : 10.70196
Core Subject : Health,
Journal of Wound Research and Technology is an essential source of information for all wound care professionals. We publish all aspects of the promotion, prevention, and treatment of wounds and associated skin conditions to improve patient care. With topics spanning surgery, endocrinology, dermatology, vascular, oncology, nursing, technology, radiotherapy, physical therapy, occupational therapy, modality therapy, and podiatry, the Journal of Wound Research and Technology continues to be the premier wound care journal for a wide range of healthcare professionals such as physicians, surgeons, nurses, midwives, podiatrists, physical therapists, radiotherapists, oncologists and occupational therapists.
Articles 5 Documents
Search results for , issue "Vol. 2 No. 2 (2025): June - October 2025" : 5 Documents clear
Total Contact Casting vs Removable Cast Walker for 12-Week Healing of Neuropathic Plantar Diabetic Foot Ulcers: A Pragmatic Randomized Trial Ayşe Demir Daysan; Mehmet Kaya Jason; Asnafi Elif Yılmaz
Journal of Wound Research and Technology Vol. 2 No. 2 (2025): June - October 2025
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v2i2.65

Abstract

Background: Diabetes-related foot ulceration remains a major clinical and health-system burden in outpatient care, with high risks of infection and amputation. Yet, evidence directly comparing non-removable total contact casts (TCC) versus removable cast walkers (RCW) on a uniform 12-week healing endpoint in routine clinics is limited. Purpose: This study compared the effect of TCC versus RCW on complete 12-week ulcer healing among adults with neuropathic plantar diabetic foot ulcers in outpatient care. Methods: In a pragmatic randomised controlled trial at Ankara City Hospital, Türkiye (2 January–30 March 2025), we enrolled 172 adults with neuropathic plantar ulcers (Wagner 1–2) meeting perfusion criteria; key exclusions were critical ischaemia and osteomyelitis. The intervention was a non-removable TCC versus RCW with standard wound care. The primary outcome was complete epithelialisation by 12 weeks, adjudicated blindly at two visits ≥2 weeks apart. Log-binomial (or Poisson-robust) models estimated risk ratios (RRs) with 95% CIs, adjusting for prespecified covariates; longitudinal percentage-area reduction and adherence-adjusted sensitivities were prespecified. Results: Among 172 participants (mean age ≈60 years; comorbidities common), 65/86 (75.6%) healed by 12 weeks with TCC versus 46/86 (53.5%) with RCW (RR 1.41, 95% CI 1.12–1.78). TCC also showed greater percentage-area reduction at 1, 2, and 3 months, consistent with a steeper healing trajectory; device-related adverse events were slightly higher with TCC, while infections requiring systemic antibiotics were similar. Findings were consistent in intention-to-treat and adherence-adjusted analyses, indicating robustness. Conclusion: TCC accelerated healing and increased 12-week ulcer closure versus RCW in routine outpatient care. Results support prioritising non-removable offloading where feasible and motivate multicentre evaluations of durability, safety, cost-effectiveness, and equitable implementation.
Prevalence, Severity (ISTAP Classification), and Risk Factors of Skin Tears in Long-Term Care Residents: A Multi-Facility Cross-Sectional Study Anna Lindström; Eriksson Johan; Karin Svensson; Michael O’Neill; Asmat Burhan
Journal of Wound Research and Technology Vol. 2 No. 2 (2025): June - October 2025
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v2i2.66

Abstract

Background: Skin tears remain a substantial, preventable harm in long-term geriatric care, yet exposure-aware benchmarks are scarce. Evidence quantifying how medical adhesive type and resident frailty relate to point prevalence and ISTAP severity in routine care is limited, hindering targeted prevention and procurement policies. Purposes: This study aimed to estimate skin-tear prevalence and severity, and to test associations of adhesive type and resident factors with these outcomes among older inpatients. Methods: In a cross-sectional study at Skånes universitetssjukhus, Malmö, Sweden (4 September–30 November 2024), we enrolled 243 adults aged >65 years meeting prespecified eligibility. Skin tears and ISTAP Types 1–3 were assessed by trained staff; adhesive exposure (acrylic vs silicone) and covariates (age, sex, CFS frailty, dermatoporosis, xerosis, comorbidities, cognition, prior tears, environment) were recorded. The primary outcomes were point prevalence and ordinal severity. We applied modified Poisson models for prevalence ratios and ordinal logistic regression for severity, adjusting for prespecified covariates, reporting effect estimates with 95% CIs. Sensitivity, subgroup, and interaction analyses were prespecified. Results: Among 243 residents (mean age 79.8; 58% women), point prevalence was 18.1%. Acrylic (vs silicone) adhesive was associated with higher prevalence (aPR 1.52, 95% CI 1.06–2.18) and greater ISTAP severity; frailty (per CFS point aPR 1.18, 95% CI 1.01–1.38), dermatoporosis (aPR 1.35, 95% CI 1.03–1.77), xerosis (aPR 1.44, 95% CI 1.03–2.03), and prior tears (aPR 1.62, 95% CI 1.09–2.41) were independent correlates. The acrylic effect was stronger at CFS ≥5 (interaction p=0.031). Findings were robust across sensitivity analyses. Conclusion: Selecting soft silicone adhesives and prioritising barrier care for frail, dermatoporotic residents may reduce skin-tear burden. Results support practice and procurement policies in geriatric/LTC wards and motivate multicentre longitudinal or pragmatic cluster-RCTs to assess durability and cost-effectiveness.
Trajectories of Transcutaneous Oxygen (TcPO2) and Healing in Chronic Limb-Threatening Ischemia: A 12-Month Longitudinal Study Kawamura Haruka; Asmat Burhan; Inoue Nanami; Fujita Kento
Journal of Wound Research and Technology Vol. 2 No. 2 (2025): June - October 2025
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v2i2.67

Abstract

Background: Chronic limb-threatening ischemia (CLTI) remains a major global burden with high amputation risk, while evidence on using transcutaneous oxygen pressure (TcPO₂) trajectories (level + slope) to guide healing decisions is limited. Most studies treat TcPO₂ as a static threshold, not a time-updated signal that could trigger earlier escalation. Purpose: This study aimed to estimate the association of TcPO₂ trajectories and revascularization with wound-healing probability among patients with CLTI over 12 months. Methods: In a prospective longitudinal cohort at a Japanese hospital (Mar 3, 2023- Mar 1, 2024), we enrolled 46 adults with tissue-loss CLTI meeting guideline ischemia criteria; acute limb ischemia and non-ischemic ulcers were excluded. Standardized wound care was provided; revascularization was time-varying (from procedure date). TcPO₂ was measured at baseline, 2, 4, 8, 12 weeks, and 6, 9, 12 months. The primary outcome was complete epithelialization sustained for ≥2 visits. Discrete-time survival models estimated adjusted odds ratios (aORs) with 95% CIs, adjusting for age, diabetes, infection, albumin, WIfI ischemia grade, and smoking; sensitivity analyses included competing risks and joint modeling. Results: Among 46 participants (mean age 71 years; diabetes 78%; CKD 41%), baseline mean TcPO₂ was 18.3 mmHg (standard care 21.2; revascularization 16.3). From baseline to Week 12, TcPO₂ rose +2.9 mmHg under standard care versus +15.8 mmHg post-revascularization. Higher time-updated TcPO₂ and positive slope independently increased healing (per 10 mmHg aOR 1.62, 95% CI 1.24-2.11; per 1 mmHg/week aOR 1.48, 1.12–1.97). Revascularization was beneficial (aOR 2.35, 1.18-4.68), while visit-level infection reduced healing (aOR 0.58, 0.36-0.92). Effects were directionally robust across sensitivity analyses. Conclusion: Trajectory-based TcPO₂ monitoring (level and slope) identifies an early, actionable window after baseline especially post-revascularization when timely escalation can improve healing. Findings support embedding serial TcPO₂ into CLTI care and motivate multicentre evaluations of effectiveness, cost, and equity.
Cold Atmospheric Plasma for Partial-Thickness Burns: Faster Epithelialization and Less Pain with Modern Dressings: A Randomized Clinical Trial Choi Ji A; Kim Seo Yun; Lee Min Jun
Journal of Wound Research and Technology Vol. 2 No. 2 (2025): June - October 2025
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v2i2.68

Abstract

Background: Partial-thickness burns remain a substantial clinical and service burden, with wide variation in practice and outcomes across settings. Evidence for cold atmospheric plasma (CAP) as an adjuvant to modern dressings is promising but limited, and its effects on healing trajectories and pain in acute burns are not well-defined. Purposes: This study aimed to test whether adding CAP to modern dressings accelerates wound healing and reduces procedural pain compared with dressings alone among adults with second-degree burns. Methods: In a two-arm, assessor-blinded randomized trial at Donghae Dong-in Hospital, Republic of Korea (February–March 2025), adults ≥18 years with partial-thickness burns presenting within 72 hours were randomized to CAP + modern dressing or dressing alone. Forty-one were randomized; 36 contributed to the primary analysis. CAP was applied 3×week for 5–8 minutes before dressing placement. The primary outcome was the percent change in wound area over 28 days. Secondary outcomes were time to complete epithelialization and pain during dressing change (VAS 0–10). Analyses used GLM repeated-measures ANCOVA (covariates: %TBSA, age) and Cox regression. Results: Among 36 analyzed participants (balanced baseline; median %TBSA 5%), CAP accelerated wound-area reduction versus control (Group×Time p<0.001; ηp²=0.25). By Day 28, CAP achieved a 17% greater reduction (adjusted Δ -17%, 95% CI −23 to −11). Pain declined faster with CAP (adjusted Δ −1.5 at Day 14; -1.9 at Day 28). Time to complete epithelialization was shorter with CAP (median 14 vs 21 days; adjusted HR 2.12, 95% CI 1.12–4.01). Effects were directionally consistent across prespecified sensitivity analyses. Conclusion: Adding CAP to modern dressings improved healing trajectories, reduced procedural pain, and shortened time to epithelialization in adults with partial-thickness burns. Findings support protocolized adoption in capable units and motivate multicentre trials with scar, microbiological, and economic endpoints.
Amputation-Free Survival and Time-to-Healing in Diabetic Foot Ulcers: A Multistate Competing-Risks Survival Analysis Asmat Burhan; Maria Angelica Dela Cruz; Grace Tan Wei Ling; Indah Susanti; Napat Kittisak; Eza Kemal Firdaus; Septian Mixrova Sebayang
Journal of Wound Research and Technology Vol. 2 No. 2 (2025): June - October 2025
Publisher : Indonesian Science Media

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70196/jwrt.v2i2.69

Abstract

Background: Diabetes-related foot ulcers (DFUs) remain a major burden in low-resource services, with wide variation in healing and limb outcomes. Evidence using competing-risks or multistate methods to accurately estimate amputation-free survival (AFS) and time-to-healing, and to identify modifiable risks within routine care remains limited. Purposes: This study aimed to estimate AFS and time-to-healing and to test associations of peripheral arterial disease (PAD), kidney function, infection, glycemia, and off-loading with these endpoints among adults with DFUs. Methods: In a multicenter prospective cohort in Indonesia (October 1, 2022-September 30, 2023), we enrolled 620 adults with active DFUs meeting predefined criteria; exclusions included prior major amputation, non-diabetic ulcers, malignancy, incomplete dates, or day-0 loss to follow-up. Outcomes were AFS (first amputation or death) and time-to-healing (complete epithelialization), each under competing risks (amputation/death or healing). We estimated cumulative incidence with Aalen-Johansen and modeled transitions using cause-specific Cox and Fine-Gray sub-distribution hazards, adjusting for prespecified covariates; multiple imputation addressed missingness, proportional hazards diagnostics were performed, and subgroup/sensitivity analyses were prespecified. Results: Among 620 participants (PAD 41.9%, neuropathy 47.1%, infection 35.6%), the 12-month cumulative incidence was: healed 71%, minor amputation 14%, major amputation 4%, and death 8%. PAD, reduced eGFR (<60), infection, and higher HbA1c worsened AFS (sHR 1.78, 1.55, 1.42, and 1.09 per 1% respectively), while higher HbA1c and infection slowed healing (sHR 0.90 and 0.71); PAD reduced healing (0.79), and off-loading improved healing (1.22). Findings were consistent across sensitivity and subgroup analyses, indicating robustness. Conclusion: Most patients healed within 12 months, yet one in four experienced amputation or death. Results support routine vascular triage or revascularization, infection bundles, glycemic or renal optimization, and mandated off-loading within DFU pathways, and motivate further prospective evaluations of durability, safety, and cost-effectiveness.

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