Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
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Perinatal Mortality in Twin Infants
Triwibowo Soedjas, Triwibowo Soedjas
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Universitas Gadjah Mada
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Ditinjau kembali berat badan lahir, nilai Apgar, cara persalinan dan kematian perinatal pada 186 bayi kembar yang lahir di Rumah Sakit Universitas Gadjah Mada, Yogyakarta, tahun 1977 sampai dengan tahun 1981,Mereka terdiri atas 80 bayi pertama dan 106 bayi kedua. Tigapuluh sembilan (21%) bayi lahir kurang bulan, 112 (60,2%) dengan berat badan lahir rendah dan 78 (42%) termasuk sebagai bayi kecil untuk masa kehamilan.Bayi kedua mempunyai nilai Apgar yang lebih rendah dibanding dengan bayi pertama. Demikian Pula presentasi kematian perinatal dan cara persalinan abnormal pada bayi kedua lebih banyak dibanding dengan bayi pertama.Key Words: twin infants - Apgar score - neonatal mortality - abnormal labour - Lubchenco curve
Some causal aspects in the decrease of function of the aging heart
Ahmad Muhammad Djoyosugito, Ahmad Muhammad Djoyosugito
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Universitas Gadjah Mada
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The process of aging of an individual has begun since his existence in the womb. Old age forms the last stage of the process.In this aging process changes take place continuously affecting the morphology and function of the individual, his systems, and organs down to the ultrastructure and biochemical reactions, probably due to "intrinsic mutation"; some of those changes are universal and some are specifically affecting certain organ, tissue or cells.In the aging process the heart is not free from these change characteristics which affect the structure of the heart muscle and the vascular wall, and also their biochemistry. All these changes have their impact on the cardiac function.In old age differences are found in the heart from its previous stages of the aging process, which among others are:1. fragmentation of some myofibrils down to complete degeneration with its specific characteristics,2. decrease of the number of mitochondria: some mitochondria show signs of degeneration, 3. heart perfusion decreases down to 80%,4, degeneration of the coronary vessels.5. a change of noradrenalin metabolism so that in the heart muscle it remains 75%,6. degenerative changes of the cardiac valves.All these changes tend to decrease the function of the heart.Key Words: aging process - "intrinsic mutation" - aging heart - myocardium degeneration - senescence
Genetic counselling
Hartono, Hartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Universitas Gadjah Mada
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Genetic counselling is a relatively new medical activity. There.are some conditions that usually need genetic counselling.ââ¬Â¢The classification of genetic disorders, their mode of inheritance and the method of establishing the diagnosis must be well understood before giving the counselling. The mode of inheritance of genic disorders and some difficulties in the diagnosis need special attention. Chromosomic disorders and embryopathies have been shortly explained ,as well.Finally, a short explanation of prenatal diagnosis, carrier detection and some methods of treating genetics disorders have been proposed so that genetic counselling can be given effectively.Key Words: genetic counselling - genetic disorders - genic disorders - prenatal diagnosis - carrier detection.
Aspek Imunobiologik Fagositosis dan Penyakit
Marsetyawan HNE, Marsetyawan HNE
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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This article describes the process and mechanism of phagocytosis, especially their immunological aspects. Phagocytosis is one of the bodys second line of defence against foreign particles, e. g. infectious and non-infectious material. The macrophage system, mononuclear and polymorphonuclear cells are responsible for phagocitizing and processing those particles, moreover they serve the processed material to the specific immunocompetent system.In addition CO the normal mechanism of phagocytosis, this article describes some disturbances which interfere with each step of phagocytosis as chemotaxis, opsonization and intracellular killing; this inadequacy results as a certain disease.Key Words: mononuclear phagocyte system - non-specific immune response - inflammation - receptor of the phagocyte cell - opsonin
The features of anaphylactic shock in Yogyakarta, Indonesia
R.H.Yudono, R.H.Yudono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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An anaphylactic shock survey was carried out in Yogyakarta, Indonesia, during November December 1981. Physicians whith private practice were asked to complete the questionnaires given by the author. These questionnaires were collected without physicians identities.One hundred out of 135 respondents have had 270 patients suffering from anaphylactic shock accident. Two hundred and sixty one (96.7%) out of 270 patients had good recovery and 9 patients (3.3%) were dead. Preconditioning disturbances which made the therapy of these shocks difficult occurred in 27 patients (10 %).The drugs which caused these shocks were penicilline (27.8%). streptomycin (20%), penicilline streptomycin combination (14%), and others (38.2%). It was revealed that the route of administration of those drugs were intramuscular injection (97.4%), intravenous injection (1.1%), subcutaneous injection (1.1%). and oral administration (0.4%).Initial treatment of these shocks done by the physicians were intramuscular epinephrine (53%), intramuscular corticosteroid (23.7%), intramuscular antihistamine (15.9%), and intramuscular el-feud (1.5%). Two patients (0.7%) were immediately referred to the hospital without initial treatment given by the physicians. The rest (5.2%) had nonspecific treatment.Key Words: anaphylactic shock - allergen - penicillin - hypersensitivety - initial drug therapy
The features of anaphylactic shock in Yogyakarta, Indonesia
R.H.Yudono R.H.Yudono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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An anaphylactic shock survey was carried out in Yogyakarta, Indonesia, during November December 1981. Physicians whith private practice were asked to complete the questionnaires given by the author. These questionnaires were collected without physician's identities.One hundred out of 135 respondents have had 270 patients suffering from anaphylactic shock accident. Two hundred and sixty one (96.7%) out of 270 patients had good recovery and 9 patients (3.3%) were dead. Preconditioning disturbances which made the therapy of these shocks difficult occurred in 27 patients (10 %).The drugs which caused these shocks were penicilline (27.8%). streptomycin (20%), penicilline streptomycin combination (14%), and others (38.2%). It was revealed that the route of administration of those drugs were intramuscular injection (97.4%), intravenous injection (1.1%), subcutaneous injection (1.1%). and oral administration (0.4%).Initial treatment of these shocks done by the physicians were intramuscular epinephrine (53%), intramuscular corticosteroid (23.7%), intramuscular antihistamine (15.9%), and intramuscular el-feud (1.5%). Two patients (0.7%) were immediately referred to the hospital without initial treatment given by the physicians. The rest (5.2%) had nonspecific treatment.Key Words: anaphylactic shock - allergen - penicillin - hypersensitivety - initial drug therapy
Genetic counselling
Hartono Hartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
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Full PDF (365.701 KB)
Genetic counselling is a relatively new medical activity. There.are some conditions that usually need genetic counselling.•The classification of genetic disorders, their mode of inheritance and the method of establishing the diagnosis must be well understood before giving the counselling. The mode of inheritance of genic disorders and some difficulties in the diagnosis need special attention. Chromosomic disorders and embryopathies have been shortly explained ,as well.Finally, a short explanation of prenatal diagnosis, carrier detection and some methods of treating genetics disorders have been proposed so that genetic counselling can be given effectively.Key Words: genetic counselling - genetic disorders - genic disorders - prenatal diagnosis - carrier detection.
Aspek Imunobiologik Fagositosis dan Penyakit
Marsetyawan HNE Marsetyawan HNE
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Show Abstract
|
Download Original
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Original Source
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Full PDF (500.162 KB)
This article describes the process and mechanism of phagocytosis, especially their immunological aspects. Phagocytosis is one of the body's second line of defence against foreign particles, e. g. infectious and non-infectious material. The macrophage system, mononuclear and polymorphonuclear cells are responsible for phagocitizing and processing those particles, moreover they serve the processed material to the specific immunocompetent system.In addition CO the normal mechanism of phagocytosis, this article describes some disturbances which interfere with each step of phagocytosis as chemotaxis, opsonization and intracellular killing; this inadequacy results as a certain disease.Key Words: mononuclear phagocyte system - non-specific immune response - inflammation - receptor of the phagocyte cell - opsonin
Perinatal Mortality in Twin Infants
Triwibowo Soedjas Triwibowo Soedjas
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (275.249 KB)
Ditinjau kembali berat badan lahir, nilai Apgar, cara persalinan dan kematian perinatal pada 186 bayi kembar yang lahir di Rumah Sakit Universitas Gadjah Mada, Yogyakarta, tahun 1977 sampai dengan tahun 1981,Mereka terdiri atas 80 bayi pertama dan 106 bayi kedua. Tigapuluh sembilan (21%) bayi lahir kurang bulan, 112 (60,2%) dengan berat badan lahir rendah dan 78 (42%) termasuk sebagai bayi kecil untuk masa kehamilan.Bayi kedua mempunyai nilai Apgar yang lebih rendah dibanding dengan bayi pertama. Demikian Pula presentasi kematian perinatal dan cara persalinan abnormal pada bayi kedua lebih banyak dibanding dengan bayi pertama.Key Words: twin infants - Apgar score - neonatal mortality - abnormal labour - Lubchenco curve
Some causal aspects in the decrease of function of the aging heart
Ahmad Muhammad Djoyosugito Ahmad Muhammad Djoyosugito
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 02 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Show Abstract
|
Download Original
|
Original Source
|
Check in Google Scholar
|
Full PDF (381.832 KB)
The process of aging of an individual has begun since his existence in the womb. Old age forms the last stage of the process.In this aging process changes take place continuously affecting the morphology and function of the individual, his systems, and organs down to the ultrastructure and biochemical reactions, probably due to "intrinsic mutation"; some of those changes are universal and some are specifically affecting certain organ, tissue or cells.In the aging process the heart is not free from these change characteristics which affect the structure of the heart muscle and the vascular wall, and also their biochemistry. All these changes have their impact on the cardiac function.In old age differences are found in the heart from its previous stages of the aging process, which among others are:1. fragmentation of some myofibrils down to complete degeneration with its specific characteristics,2. decrease of the number of mitochondria: some mitochondria show signs of degeneration, 3. heart perfusion decreases down to 80%,4, degeneration of the coronary vessels.5. a change of noradrenalin metabolism so that in the heart muscle it remains 75%,6. degenerative changes of the cardiac valves.All these changes tend to decrease the function of the heart.Key Words: aging process - "intrinsic mutation" - aging heart - myocardium degeneration - senescence