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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 14 Documents
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Search results for , issue "Vol 37, No 01 (2005)" : 14 Documents clear
Incompleted gestational age as a risk factor for developmental disorder at 6 up to 36 months of age. Pramudito Pramudito
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 01 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: In developed countries, survival rate of preterm baby with gestational period more than 26 weeks has increased. Most studies on developmental outcomes were conducted on preterm baby with gestational period of less than 32 weeks. On the other hand, in developing countries the mortality rate of preterm baby with gestational period of less than 32 weeks is still high.Objective: To assess whether the incompleted gestational age is a risk factor for developmental disorder at 6 up to 36 months of age.Methods: Sixty four subjects born between 2001 April 1 to 2004 January 31 in Dr. Sardjito Hospital were enrolled, consisted of 31 children with incompleted gestational age (exposed group) and 33 children with completed gestational age (unexposed group). The developmental milestone was assessed using the DenverDeve/opmenta/ Screening Test/DDST (Denver //). Age line adjusment is used for exposed grou when the subject was born 4 weeks before completed gestational age and less than 3 years old.Results: There was no statistically significant diferrence on the prevalence of developmental, disorder at 6 to 36 months of age between exposed group and unexposed group in every area i.e. for gross motor: RR (95% Cl): 0,87 (0,24-3,19); language RR (95% Cl ): 1,48 (0,30-7,23 ) and personal social RR (95% Cl): 1,10 (0,10-17,83) or developmental conclusion: RR (95% Cl): 0,75 (0,23-2,48Conclusion: On the basis of developmental screening using DDST (Denver 11) incompleted gestational age (32-36) weeks was not a risk factor for developmental disorder at 6 to 36 months of age. Key words: incompleted gestational age - development disorder - Denver Developmental Screening Test/ DDST (Denver ll).
Laboratory blood group examination of proteolysis degradation human blood Beta Ahlam Gizela Beta Ahlam Gizela
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 01 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Blood group examination has many purposes and one of them is identification. In several forensic cases there is incompatibility of blood group in corpse and in other evidences usually used blood group examination is serum agglutination method. From the previous study, it was found that there was increasing osmotic fragility of red cell. For that reason, we need to know how the result of blood group tests in degradation human blood.Objective: The purpose of this study is to know blood groups of proteolysis degradation human blood.Method: This study was an experimental study. The subjects was people that have blood group A, B, AB, and 0. Blood samples were examined serially for blood grouping, when the samples were just taken, after stored in room temperature, with addition of protease enzyme (tripsin) in 20 seconds, 1 hour, 2 hours, 3 hours, and 24 hours, and without protease enzyme after 7 days. The data was analysed using chi-square statistics.Result: This study showed there was significant proportionally different(p<0.05) in blood group chang-ing of non-0 blood group to be 0 blood group after stored the blood in 3 hours with protease enzyme addition (5(16.68%)). In 24 hours, it was showed that all of non-0 blood group changed to 0 blood group (100%). Blood group examination of the blood without protease enzyme addition stored for 7 days showed that all of them were observed as 0 blood group.Conclusion: There is blood group changing by agglutination method from non-O blood group to 0 blood group in proteolysis degradation blood. Key words: blood group - proteolysis degradation - group changing
Accelerated phase of chronic mylogenous leukemia in paediatric with metabolic acidosis and poor nutritional status. A case report Riadi Wirawan Riadi Wirawan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 01 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

We reported a case of a twelve year old girl diagnosed as chronic myelogenous leukemia (CML), metabolic acidosis and poor nutrional status. The chief complaints were bulging abdomen, without abdominal pain, nausea and vomiting, accompanied by episodic pain in the lower extremities and buttocks without swelling or redness. Physical examination revealed hepatosplenomegaly, multiple lympadenopathy, body weight for age 54% of P50 and body weight for height 60% of P50; under P65. The laboratory findings were normochromic normocytic anemia, leucocytosis with shift to the left, myelocyte and neutrophil domination, thrombocytosis, hypercellular bone marrow with hyperactive granulopoiesis and megakaryocyte, erythropoiesis and NAP score decreased and the result of blood gas analysis was partially compensated metabolic acidosis with hypoxemia.Key words: Chronic myelogenous leukemia - metabolic acidosis - poor nutritional status - infection - hydroxyurea, cytosar 
Antioxidant activity of mengkudu fruit juice (Morinda citrifolia) and the role as an inhibitor of advanced glycation and products (AGES) by glycosilation reaction Eko Suhartono Eko Suhartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 01 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Mengkudu is a traditional plant with active compound that has antioxidant activity. Diabetes mellitus complication has causative link with AGEs formation that involves free radical. Objective: To know antioxidant activity of mengkudu and the role to inhibit AGEs formation. Methods: This experiment used pre and post test control group design. Antioxidant activity was deter-mined'by reacting the mengkudu juice with 2,4 dinitrophenylhydrazin (DNPH) and analyzed with spectro-photometer a.=390 nm. AGEs absorbancy was measured every 48 hours until 20 days with spectropho-tometer ?=340 nm. Dicarbonyl level was determined with DNPH method that was developed by Uchida and modified by Sadikin.Result: Antioxidant activity of 0.25 g/ml mengkudu juice (Morinda citrifolia) was 125.46±27.79%.Beside that, mengkudu juice can inhibit advanced glycation end products (AGEs) formation.Conclusion: Mengkudu juice can decrease AGEs formation and has antioxidant activity. Key words: antioxidant - mengkudu juice - AGEs - glycosilation 

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