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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
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Search results for , issue "Vol 4 No 2 (2016)" : 30 Documents clear
Optimasi Hidroksipropil Metilselulosa dan Carbopol terhadap Moisture Content dan Laju Pelepasan Patch Ibuprofen In Vitro (Optimization of Hydroxypropyl Methylcellulose and Carbopol for Moisture Content and Release Rate of Ibuprofen Patch In Vitro) Kristine Dwi Puspitasari; Dwi Nurahmanto; Lidya Ameliana
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Ibuprofen is non steroidal antiinflammatory drug (NSAID) of the propionic acid class which is widely used for the treatment of rheumatoid arthritis. Ibuprofen patch is an effective approach evading ibuprofen's adverse effect in the GI tract and first pass effect. The function of polymer is to control the drug release from the patch. The aims of this study were to determine the effect of hydroxypropyl methylcellulose (HPMC) K4M and carbopol 934 combination on the moisture content (MC), in-vitro drug release, and to obtain the optimum formula of those polymers. Ibuprofen patch were prepared into three formulas based on simplex lattice design with the ratio of HPMC K4M : carbopol 934, that were 1 : 0, 0.5 : 0.5, and 0 : 1. Design expert software was used to obtain the optimum formula of both polymers. The results of this study showed that patch with HPMC K4M : carbopol 934 (0.5 : 0.5) gave the best MC and the in-vitro drug release. The optimum formula was HPMC K4M and carbopol 934 with the ratio of 0.5 : 0.5. Keywords: ibuprofen, patch, HPMC, carbopol
Hubungan antara Tingkat Kecemasan dengan Kualitas Hidup pada Pasien Chronic Kidney Disease (CKD) yang Menjalani Hemodialisis di RSD dr. Soebandi Jember (Correlation between the Level of Anxiety and Quality of Life of Chronic Kidney Disease (CKD) Patients Novita Dwi Cahyani,; Justina Evy Tyaswati; Dwita Aryadina Rachmawati
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Chronic Kidney Disease (CKD) is a chronic disease that results in the progressive decline in renal function and irreversible. Patients with end stage CKD requiring hemodialysis therapy. CKD patients who undergo hemodialysis therapy largely experiencing symptoms of anxiety and changes in quality of life. The aim of this study was to determine the correlation between the anxiety level and the quality of life of patients with CKD during hemodialysis therapy at dr. Soebandi Regional Hospital Jember. Research using Cross Sectional Design with the total number of respondents as many as 30 people and was carried out in November 2015. The respondent's anxiety level was measured using a HARS questionnaire and assessment of quality of life using the WHOQOL-BREF questionnaire. The results revealed respondents with mild anxiety were 16,67% (10% with good quality of life and 6,67% with bad quality of life), respondents with moderate anxiety were 40% (10% with good quality of life and 30% with bad quality of life), and respondents with severe anxiety were 43,33% with bad quality of life. Spearman correlation test showed the significance (p) 0,00 with correlation coefficient (r) – 0,517. Thus, it can be concluded that there was a correlation between the level of anxiety and quality of life of CKD patients during hemodialysis therapy at dr.Soebandi Regional Hospital Jember.   Keywords: Chronic Kidney Disease (CKD), hemodialysis, anxiety, quality of life.
Pengaruh Konseling KB Pada Ibu Hamil Trimester III terhadap Keikutsertaan KB Pasca Persalinan di Kecamatan Sukowono Kabupaten Jember (The Effects of Family Planning's Counseling Among Third Trimester Pregnancy Women to Participation of Postpartum Family P Vita Khusnul Khotimah; Ni'mal Baroya; Pudjo Wahjudi
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Posttpartum family planning was very important to prevent unintended pregnancy. Based onthese data, Sukowono Subdistrict has lowest postpartum FP participant that was any 1 personthan another subdistrict. The low service caused by the lack of FP counseling treatmenttherefore it will impact to the increasing of unmet need. This research aims to know effects offamily planning's counseling among third trimester pregnancy women to participation ofpostpartum family planning in sukowono subdistrict, Jember District. This type of research wasquasi-experimental research with the type of Community Trial. The study was conducted inNovember 2014 until July 2015, in Sukowono Subdistrict. The total respondents were 45 peopleand the randomization ratio was 1:2 for the control and intervention groups. Result showed thatgroup that was given counseling have knowledge and attitude higher than group that was notgiven counseling The analysis results of FP counseling effect to postpartum FP participationshow experimental group percentage of respondents who participate to postpartum FP washigher than control group, and there was significant relationship between counseling treatmentand postpartum FP participation. The analysis results also showed there was no differencebetween planning and realization of postpartum FP participation in group that was given FPcounseling.Keywords: Family Planning's Counseling, Postpartum Family Planning
Sitotoksisitas Minyak Mesoyi (Cryptocarya massoy) terhadap Sel Vero (Cytotoxicity of Mesoyi Oil (Cryptocarya massoy) on Vero Cell Lines) Bawon Triatmoko; Triana Hertiani; Agustinus Yuswanto
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Mesoyi oil distilled from the bark of Cryptocarya massoy have been used for traditional treatment of various ethnicities. However, its safety use has not been widely studied. This study aimed to investigate the cytotoxicity of mesoyi oil on vero cells in vitro. The Inhibitory concentration 50% (IC50) of mesoyi oil is evaluated using MTT assay. The results indicated that the mesoyi oil exhibited cytotoxic effects on vero cells with IC50 value of 97.4 μg//mL. This call for further studies to evaluate the cytotoxic activity in vivo. Keywords: cytotoxicity, essential oil, cryptocarya massoy, vero cell
Perbedaan Tingkat Kecacatan Klien Kusta yang Aktif dan Tidak Aktif Mengikuti Kegiatan Kelompok Perawatan Diri (KPD) di Kabupaten Jember (The Difference in Impairment Level of Leprosy Clients who were Active and Inactive participating Self Care Group ( S Frandita Eldiansyah; Wantiyah Wantiyah; Siswoyo Siswoyo
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Leprosy is an infectious disease caused by Mycobacterium leprae due to problems quite complex involve physical, psychological, social, economic, cultural, and spiritual problems. Physical problems such as impairment experienced by clients leprosy generally occur in the feet, hands, and eyes. Self-care group is a group of leprosy patients who come together to support each other primarily in prevention and reduction disabilities, also to find solutions for problems related to leprosy. The aim of this research was to analyze the difference in impairment levels of leprosy clients who were active and inactive participating Self Care Group (SCG) activities in Jember. This research used historical cohort study. The sampling collection technique used was total sampling involving 44 individuals, divided into 23 active leprosy clients and 21 inactive leprosy clients who participate SCG. Data analysis used Mann Whitney U-test with the significance level of 95% (α = 0.05). The research result showed that the average value of the active leprosy clients in impairment degree was 0.83 while the impairment degree of the inactive leprosy clients was 2.57. Data analysis showed that there was significant difference in impairment levels of leprosy clients who were active and inactive in participate Self Care Group (SCG) activities in Jember (p value 0.042, α = 0.05). Nurses are expected to create new innovations in the implementation of the SCG to increase participation of leprosy client's in the activities of the SCG then the impairment of leprosy client can be prevented and treated. Keywords: Leprosy, Impairment levels, Self Care Group (SCG)
Gambaran Status Kebersihan Rongga Mulut dan Status Gingiva Pasien RSGM Universitas Jember Oktober-November Tahun 2015 (The Description of Oral Hygiene Status and Gingival Status of Patients in Dental Hospital of Jember University on October-November 2015) Cici Widya Anggraini; Melok Aris Wahyukundari; Peni Pujiastuti
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background : Oral hygiene is very important to be kept for aestetic, phonetic, mastication function and health. There is a relationship between oral hygiene and gingival desease. Poor oral hygiene will increase the severity of gingival disease. However, some people still consider that oral hygiene issue is not something important. Purpose : To find out the status of oral hygiene and gingival status of patients in Dental Hospital of Jember University and reviewed by age, gender and education. Metode : This study was a descriptive study with cross sectional approach. The samples were all new patients of Dental Hospital of Jember University on October-November 2015. The oral hygiene status was assessed by Oral Hygiene Index-Simplified (OHI-S) and gingival status was assessed by Gingival Index (GI). Result : There were 35,84% of sample had a good oral hygiene, 54,87% had a medium oral hygiene and 9,29% had a poor oral hygiene. There were 7,08% of sample had a normal gingival, 58,85% had a light gingival inflamation, 33,63% had a moderate gingival inflamation, and 0,44% had a severe gingival inflamation.Keywords : Gingivitis, GI, OHI-S, Oral hygiene.
Penentuan Kadar Fenol Total pada Ekstrak Daun Tanaman Menggunakan Metode Spektroskopi NIR dan Kemometrik (Determination of Total Phenolic in Leave Extracts Using Spectroscopy NIR and Chemometric) Fracilia Arinda Ratnasari; Lestyo Wulandari; Nia Kristiningrum
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Phenols are group which having one or more hydroxyl groups which attached in aromatic ring and are found in plants. The aim of this research was to study whether NIR and chemometric methods could be used to determine the total phenol content of leave extracts. These methods were compared to UV-Vis spectrophotometry. Phenol was extracted from plant leaves by ultrasonic and maceration. NIR spectral data of selected leave extracts were correlated with total phenol content using chemometric. In this study, the chemometric method that used for quantitative and qualitative analysis were Partial Least Square (PLS) and Linear Discriminant Analysis (LDA), respectively. The PLS R2 calibration was 0.9920369 and RMSEC was 2.0049472. In addition, the R2 of LOOCV and 2-Fold-Cross-Validation were 0.9939401 and 0.9834646, respectively. Furthermore, LDA gave accuracy of 100%. The significance of phenol total that have been measured by NIR and UV-Vis spectrophotometry was evaluated with paired samples T-test and gave no significant difference. In conclusion, total phenol content can be measured using NIR and chemometric methods.   Keywords: phenol, chemometric, LDA, NIR, PLS
Pengaruh Stres Fisik terhadap Kadar Kreatinin Serum Tikus Wistar Jantan (Rattus norvegicus) (The Effect of Physical Stress on Serum Creatinine of Male Rattus norvegicus) Putu Ratih Pradnyani Dewi; Hairrudin Hairrudin; Rena Normasari
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Physical stress is a condition that caused by severe physical activities which can increase free radicals production causing oxidative stress. Oxidative stress causing the organs failure include the kidney. It damage glomerulus causing decrease in GFR and tubular cell damage causing cumulation of creatinine and raise creatinine serum. This study investigated the difference of serum creatinine of male Rattus norvegicus with physical stress and without physical stress. Ten male Rattus norvegicus aged 2-3 months were divided into two groups : control and treatment group. Control group without physical stress but treatment group was given physical stress 30 minutes of swimming stress in the morning everyday for 10 days. The creatinine serum measured by Jaffe reaction. The normal range of serum creatinine for Rattus norvegicus was 0,578-1,128 mg/dl. The result of serum creatinine for control group was 0,52 mg/dl and treatment group was 0,62 mg/dl,both still in normal range. The analysis using Mann Whitney showed the significance of 0,23 (p>0,05). We can conclude that there was no difference of serum creatinine of male Rattus norvegicus with physical stress and without physical stress. Keywords: physical stress, oxidative stress, serum creatinine
Determinan Kejadian Stunting pada Anak Balita di Wilayah Kerja Puskesmas Soromandi Kabupaten Bima Nusa Tenggara Barat (Determinan Incidence of Stunting in Children Under Five Year at Puskesmas Soromandi Bima district of West Nusa Tenggara) Mirham Nurul Hairunis; Ninna Rohmawati; Leersia Yusi Ratnawati
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Stunting is linear growth disturbance caused by the nutrient intake of chronic malnutritionand chronic or recurrent infections showed with height z-score for age (H / A) <-2 SDbased on the standard WHO. Based on the results of Nutritional Status Monitoring inBima, the prevalence of stunting for each year has increased. The prevalence of stuntingin 2011 amounted to 23.61%, in 2012 amounted to 30.3%, and in 2013 amounted to53.2%. Soromandi district is one of the districts with the highest prevalence of stunting inBima. This study aimed to analyze the determinants of the incidence of stunting inchildren under five year in Puskesmas Soromandi Bima district of West Nusa Tenggara.This research is an observational analytic study with cross sectional approach. This studyshows that there was no significant relationship between food intake, genetic factors,status BBLR with the incidence of stunting and no significant correlation between geneticfactors with the incidence of stunting. The factors that most influence the incidence ofstunting was exclusive breastfeeding.Keywords: Stunting, Children Under Five Year, Determinan
Pengaruh Pemberian Ekstrak Etanol Brokoli (Brassica oleracea) terhadap Kadar SGOT dan SGPT Tikus Wistar yang Diinduksi DMBA (The Effect of Ethanolic Extract of Broccoli (Brassica oleracea) on SGOT and SGPT of Wistar Rats Induced by DMBA) Rizka Nuzula Wardani; Elly Nurus Sakinah; Yudha Nurdian
Pustaka Kesehatan Vol 4 No 2 (2016)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

DMBA is a product of incomplete burning which can cause free radicals in human. The metabolism of DMBA by Cytochrome P450 in liver causes hepatocyte DNA damage and decrease endogenous antioxidant. Broccoli contains flavonoid which can act as an antioxidant by inhibiting formation of free radicals through hydrogen atom donation to free radicals. This research aimed to analyze the effect of ethanolic extract of broccoli on SGOT and SGPT of wistar rats induced by DMBA. This research used 24 rats divided into six groups: control group, negative control group, and four treatment groups with broccoli ethanolic extract of 250 mg/kgBW, 500 mg/kgBW, 1000 mg/kgBW, and 2000 mg/kgBW for 7 days. The SGOT and SGPT levels of control group were 70,36 U/L and 33,97 U/L; negative control group 107,16 U/L and 56,21 U/L; the first treatment 101,50 U/L and 49,33 U/L; the second treatment 85,32 U/L and 43,67 U/L; the third treatment 84,11 U/L and 40,84 U/L; and the fourth treatment 81,28 U/L and 35,18 U/L. The result of One Way Annova test for SGOT was p=0,012 while SGPT was p=0,003. In this study, ethanolic extract of broccoli could protect hepatocyte by decreasing SGOT and SGPT levels.   Keywords: ethanolic extract of broccoli, SGOT and SGPT levels, DMBA

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