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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
Search results for , issue "Vol 5 No 1 (2017)" : 30 Documents clear
Perbedaan Tingkat Kecenderungan Depresi pada Akseptor Berbagai Jenis Kontrasepsi Hormonal di Puskesmas Sumbersari Kabupaten Jember (The Difference of Depression Tendency Level on User of Several Hormonal Contraception Types in Sumbersari Primary Health Care, Jember) Ghuiranda S Ramadhan; Alif Mardijana; Hairuddin Hairuddin
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Hormonal contraception is a method to prevent pregnancy that contains synthetic progesterone and estrogen. There are three types of hormonal contraception, i.e injection, pill, and implant. The side effect of hormonal contraception is depression. The aim of this research was to determine the difference of depression tendency level on several hormonal contraception types in Sumbersari Primary Health Care, Jember. This research method was analitical observational with cross sectional approache. Sample total were 103 hormonal contraception's acceptors who were recruited by proportionate stratified random sampling technique. Sample were interviewed using Hamilton Depression Rating Scale (HDRS) as the screening depression tendency level. Kruskal wallis statistical test showed significance point 0,00 (p<0,05). Post Hoc analysis with Mann-Whitney test between pill and injection acceptors group showed significance point 0,001 (p<0,05), 0,001 (p<0,05) for injection and implant acceptors group, then 0,000 (p<0,05) for pill and implant. In conclusion there is significance difference of depression tendency level in several types of hormonal contraception in Sumbersari Primary Health Care, Jember. Keywords: depression tendency level, hormonal contraception, HDRS
Efektivitas Penyuluhan Metode Aplikasi Inovatif GIGI SEHAT dan Pertunjukan Panggung Boneka terhadap Pengetahuan Kesehatan Gigi dan Mulut Siswa Kelas IV & V SDN Kebonsari 02 Jember (The Effectiveness Counseling of Innovative Application GIGI SEHAT Method and Puppet Show to Dental Health Knowledge for IV & V Grade Students of SDN Kebonsari 02 Jember) Qatrunnada Fath; Hestieyonini Hadnyanawat; Kiswaluyo .
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: UKGS of Public Health Office in 2009 shows much the elementary school children are treated in Community Health Center because of teeth decay in the amount of 41,38%. Counseling in UKGS all this time uses lecture method which needs dentists, times, and energy in implementation. In fact human resources to do the UKGS are inadequate, so need an alternative method which is suited. Objective: To know the effectiveness of counseling with innovative application GIGI SEHAT and puppet show to dental health knowledge for IV & V grade students of SDN Kebonsari 02 Jember. Method: The subject were students in IV and V grade of SDN Kebonsari 02 Jember. Students are divided into three groups counseling method, there were innovative application GIGI SEHAT, puppet show and lecture. Research procedure was divided into three stages which were pretest, counseling, and post test. Results and Conclusions: The data before and after counseling all of the methods were analysed with Paired t-test, and the result of application GIGI SEHAT and lecture showed that were significant difference (p<0,05) and the puppet show was not significant. The results of three different test methods used One Way Anova Test showed there was the significant difference between three method (p>0,05). The different test counseling effectiveness of each methods performed further test used Independent T-test showed that application GIGI SEHAT and puppet show, application GIGI SEHAT and lectures there were the significant differences ( p< 0.05 ).  Keywords: Dental Health Counseling, Innovative Applications GIGI SEHAT, Lecture, Puppet Show, UKGS
Distribusi Pencabutan Gigi Berdasarkan Karakteristik Sosiodemografi pada Pasien RSGM Universitas Jember Periode Januari-Desember 2014 (Distribution of Tooth Extraction Based on Sociodemographic Characteristic of Dental Hospital of University of Jember Pat Zulfa Fithri; Abdul Rochim; Zainul Cholid
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: The number of tooth extraction in Dental Hospital of Unversity ofJember increased on 2014. It might be caused by inapropriate dental health program.Information about distribution of tooth extraction by sociodemographic characteristic isneeded to make apropriate dental health program to decrease the number ofextraction in Dental Hospital of University of Jember. Purpose: To find out thedistribution of tooth extraction by sociodemographic characteristic in Dental Hospitalof University of Jember patients on January-December 2014. Methods: A descriptiveresearch used medical records from new Dental Hospital of University of Jemberpatients experienced tooth extraction on January-December 2014 with completemedical record and were ≥17 years old. The data were divided into groups based onsociodemographic characteristic (age, sex, education level). The data of tooth type,number, and reason of tooth extraction were collected from each sociodemographiccharacteristic groups. The results were presented in graphics and tabels. Result andConclusion: Female, elderly, and basic education level had higher number of toothextraction. Periodontal disease was the main reason of tooth extraction in all groups.Posterior teeth, especially mandibular first molar, were more frequently extracted inthe most groups.Keywords: dental health program, sociodemographic, tooth extraction
Efek Hepatoprotektif Ekstrak Etanol Brokoli (Brassica oleracea L. var. italica) terhadap Kerusakan Histologis Sel Hati Tikus Wistar yang Diinduksi DMBA (Hepatoprotective Effect of Ethanolic Extract of Broccoli (Brassica oleracea L. var. italica) on the Histologically Damage of Wistar Rats Liver Cell Induced by DMBA) Muhtar Ady Kusuma; Elly Nurus Sakinah; Rosita Dewi
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

DMBA (7,12-Dimethylbenz(α)antracene) is one of Polycyclic Aromatic Hydrocarbon’s form that is abundant on air pollution, i.e. automobile exhaust, cigarette smoke, and wood stoves. DMBA is metabolized in liver result in DMBA-DE. DMBA-DE is a free radical compound that has hepatotoxic effect. Broccoli contains flavonoid that has antioxidant effect. It can stabilize DMBA-DE radical compound. This research was conducted to investigate the hepatoprotective effect of ethanolic extract of broccoli on the damage of rat’s liver cells induced by DMBA. This research used 30 white male rats that was divided into 6 groups: normal control (aquadest), positive control (DMBA) and the treatment groups(using brocolli ethanolic extract with dose : 250, 500, 1000, and 2000 mg/kgBB). The treatment was given for 7 days followed by single-dose DMBA 15 mg/kgBB induction in the 8th day. Histological appearance of liver cells were examined on the 12th day. Data were analyzed by using Kruskal Wallis test followed by Mann Whitney. The result showed that there was a significant difference among the groups with p<0.05. In conclusion, there were some differences of hepatoprotective effect of broccoli ethanolic extract on the histologically damage of rats liver cells induced by DMBA. Keywords: ethanolic extract of broccoli, DMBA, histopathology, hepatoprotective
Uji Daya Hambat Ekstrak Metanol Daun Ungu (Graptophillum pictum (L.) Griff) terhadap Pertumbuhan Bakteri Saluran Akar Gigi (Inhibition Test of Purple Leaf (Graptophillum pictum (L.) Griff) Methanol Extract toward Root Canal Bacteria's Growth) Resti Ayu Indriana; Pudji Astuti; Atik Kurniawati
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: Root canal bacteria in necrotizing pulp are dominated by polymicrobial bacterial colonization. Bacteria control were performed by using antribacterial irrigation. Purple leaf methanol extract contains triterpenoids, alkaloids, flavonoids, glycosides, saponins, and tanins which are to own antibacterial capability. Objective: To determine a wide range of consentrations, the minimal concentration of purple leaf methanol extract which able to inhibit the growth of root canal bacteria, and how much is the concentration of the purple leaf methanol extract which is equivalent to 2.6% sodium hypochlorite. Methods: The method was used well diffusion. Antibacterial test was indicated by the existance of the inhibition zone around the well hole. Total samples used were 56 samples for  each 7 group treatment, which are concentration 100%, 50%, 25%, 12,5%, 6,25% of purple leaf methanol extract, 2.6% of sodium hypochlorite, and sterile water. The results of the study was then tested by the statistical parametric one way ANOVA and LSD. Results and Conclusion: The concentration of purple leaf methanol extract which ables to inhibit the growth of root canal bacteria is 12,5%, 25%, 50%, and 100% also the minimum concentration is 12,5%, and the concentration of purple leaf methanol extract which is equivalent to 2.6% of sodium hypochlorite is concentration of 25%.Keywords: Antibacterial, Root Canal Bacteria, Purple Leaf Methanol Extract, Graptophillum pictum (L.) Griff
Efikasi Diri, Kepatuhan, dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 (Self Efficacy, Adherence, and Quality of Life of Patients with Type 2 Diabetes) Handono Fatkhur Rahman; Yulia Yulia; Lestari Sukmarini
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Self-efficacy and adherence are important factor in improving the quality of life of patients with type 2 diabetes. This study aimed to determine the relationship between self-efficacy and adherence to the quality of life of patients with type 2 diabetes mellitus. This study was a cross-sectional, with sample of 125 patients with type 2 diabetes mellitus. The Diabetes Management Self-Efficacy (DMSES), the Diabetes Activities Questionare (TDAQ), and the Diabetes Quality of Life (DQOL) were employed as instruments. The results showed that self-efficacy (0.0005), and adherence (0.0005) were significantly associated with quality of life and the most dominant variable is adherence. Multivariate test results indicate that the variable self-efficacy, adherence, depression, and education level determines quality of life of diabetic patients. This study suggestion the need for nursing assessment and interventions that focus on the self-efficacy and adherence diabetes mellitus patient. Keywords: self efficacy, adherence, quality of life, diabetes type 2
Optimasi Konsentrasi Hidroksipropil Selulosa dan Polivinilpirolidon dalam Sediaan Buccal Film Simvastatin (Optimization Of Hydroxypropyl Cellulose and Polyvynylpyrolidone Concentration in Simvastatin Buccal Film) Nurul Qomariyah; Lidya Ameliana; Lusia Oktora Ruma Kumala Sari
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i1.3951

Abstract

Simvastatin, an antihyperlipidemia drug belongs to HMG-CoA reductase inhibitor, has extend first-pass metabolism and low bioavailability (5%) with 95-98% protein bond and short half-life (2 hours). The problem of low bioavailability can be solved by buccal delivery systems with producing simvastatin mucoadhesive buccal film. Concentration of HPC and PVP can affect the value of simvastatin release and mucoadhesive strength of film. Optimization using factorial design method determine the optimum concentration of HPC and PVP with highest simvastatin release and mucoadhesive strength. Solvent casting method used for preparation of 4 formula according to factorial design. The result was formula A (FA) with HPC and PVP concentration ratio (50: 10) gave the highest simvastatin release at 95.41% and the highest mucoadhesive strength at 73.37 grams. FTIR analysis results of FA indicated that there were no change in the functional groups on simvastatin as an active ingredient, and the mucoadhesive residence time showed that FA buccal films can be attached to the goat buccal tissues for 186 minutes. Keywords: Buccal film, mucoadhesive, simvastatin, HPC, PVP, factorial design. 
Pengaruh Minyak Ikan Lemuru (Sardinella longiceps) terhadap Ekspresi Tumor Necrosis Factor (TNF-α) Kartilago yang Diinduksi Complete Freund's Adjuvant (Effect of Lemuru (Sardinella longiceps) Fish Oil on Tumor Necrosis Factor (TNF-α) Expression of Cartilage that Induced by Complete Freund's Adjuvant) Kiki Andari; Rena Normasari; Muhammad Hasan
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Osteoarthritis is a chronic joint disorder with weakening and disintegration of the joint cartilage followed by the growth of new bone and cartilage. TNF-α is one of the inflammatory mediator that plays an important role in the progression of osteoarthritis. In the others hands, lemuru (Sardinella longiceps) fish oils that contain EPA and DHA has an anti-inflammatory effect. The purpose of this study was to investigate the effect of lemuru fish oil on decreasing the expression of TNF-α in cartilage that induced by Complete Freunds Adjuvant. This was a experimental design study with randomized post test only control group design. The sample was divided into 2 groups: the negative control group (K-) and the treatment group (P), each group was divided into three subgroups based on duration of lemuru fish oils treatment, 7th, 14th and 21st days. TNF-α expression data was obtained from immunohistochemical observations on tibiofemoral articular cartilage. The result showed that the expression of TNF-α in the treatment group is lower than the negative control group and One Way Anova test showed that there is significant difference between groups (p = 0.000). We can conclude that lemuru (Sardinella longiceps) fish oil decreased the expression of TNF-α. Keywords: Osteoarthritis, TNF-α, lemuru (Sardinella longiceps) fish oil, cartilage
Insidensi dan Distribusi Penderita Angular Cheilitis pada Bulan Oktober-Desember Tahun 2015 di RSGM Universitas Jember (Incidence and Distribution of Angular Cheilitison October-December 2015 at DentalHospital of Jember University) Herlin Sriwahyuni; Sri Hernawati; Ayu Mashartini
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Background: The high prevalence, complexity and negative impacts of angular cheilitis are affecting the patient quality of life indicates the importance of the disease caring and treating. Collecting data is required to identifying the disease frequency in a population as an early step attempted to planing, preventing, caring, and healing the disease. Objective: to determine the incidence rate of angular cheilitis at Dental Hospital of Jember University on October-December 2015, and the distribution based on age, sex, nutritional status, and residece. Method: This observasional descriptive study used cross sectional survey design. The study was conducted by identifying sample with angular cheilitis patient were found on October-December 2015 at Dental Hospital of Jember University. Result and conclusions: The incidence rate is 6,7%. The distribution based on age, sex, nutritional status and residence are most common in children 5-11 (89,2%), male (62,5%), malnutrition status (52%) and rural (59%), so that the rate is estimate the risk factor of angular cheilitis increase in children, male, malnutrition and villagers.  Keywords: Angular Cheilitis, Distribution, Incidence
Optimasi Komposisi Polietilen Glikol dan Lesitin sebagai Kombinasi Surfaktan pada Sediaan Nanoemulsi Kafein (Optimization of Polyethylene Glycol and Lecithin Composition as Surfactant Combination in the Caffeine Nanoemulsion) Dessy Dwi Risky Ayuningtias; Dwi Nurahmanto; Viddy Agustian Rosyidi
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v5i1.5386

Abstract

Caffeine is one of alkaloids that have the potential to skin cancer treatment. Caffeine is hydrophilic with log-P value of 0.07 that makes difficult to penetrate to the stratum corneum. Nanoemulsion is one of system which made to increase drug penetration. One of the important component in the nanoemulsion is a surfactant that acts as a unifier between the oil and water phases to form one phase that isotropic and thermodynamically stable. The presence of lipophilic component in the surfactant can affect the skin barrier disturb, thus increasing penetration. The aims of this study was to find the best composition of the PEG-400 and lecithin as surfactant combination to obtain a nanoemulsion that is safe, stable, and increasing penetration of caffeine. The experiment was conducted using a factorial design method which observed responses of flux value and viscosity deviation. The viscosity deviation and flux were analyzed using Design Expert 10.0 trial to determine the optimal formula of caffeine nanoemulsion. The results obtained optimal formula of nanoemulsion that has composition of PEG-400 as 32% and lecithin as 7% . Prediction of viscosity deviation and flux value of optimal formula was 0,034 cP and 0.514 µg cm-2min-1. Keywords: caffeine, nanoemulsion, PEG-400, lecithin

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