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INDONESIA
Indonesian Journal of Urology
Published by Universitas Airlangga
ISSN : 0853442X     EISSN : 23551402     DOI : 10.32421
Core Subject : Health,
Health Professions Medicine & Pharmacology Public Health
The aim of Indonesian Journal of Urology is to encompass the whole spectrum of urology. The journal publishes papers on a wide range of urological issues such as oncology, functional urology, reconstructive urology, laparoscopy, robotic surgery, endourology, female urology, andrology, pediatric urology, and sexual medicine. We welcome authors for original article (research), review article, interesting case reports, special article, clinical practices, and medical illustrations that focus on the clinical area of urology.
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Articles 12 Documents
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Search results for , issue "Vol 29 No 2 (2022)" : 12 Documents clear
THE EFFECT OF SUKUN LEAF (ARTOCAPTUS ALTILIS) EXTRACT ON RENAL ISCHEMIA/REPERFUSION INJURY IN WISTAR RATS WITH PARAMETER OF KIDNEY HISTOPATHOLOGICAL FINDINGS SERUM CYSTATIN-C AND SERUM CYSTATIN-C
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.444

Abstract

Objective: To determine the effects breadfruit leaf extract (Artocaptus altilis)in Wistar rats, which had induced renal ischemic-reperfusion injury, with evaluation of serum cystatin C level and kidney histopatologic findings. Material & Methods: A total of 30 Wistar rats, three groups of ten, were included in the study and were performed in Bandung Eijkman Animal Laboratory. In group I (sham group), a right nephrectomy was done. In group II (control), a right nephrectomy was also done and the left renal pedicles were occluded for 60 minutes and reperfused for 60 minutes. In group III (treatment), the treatment was equal with group II, and breadfruit leaf extract (4.75%) was administered intraperitoneally. At the end of the study, a left nephrectomy was performed on all groups. Afterward, serum cystatin C levels and kidney histopathological findings of all rats were examined. Data were analyzed by an unpaired numerically comparative analysis with SPSS 20.0 software. Results: The mean of serum Cystatin C in group I was 3183.2 ± 680.9 pg/dL, group II was 3776.4 ± 326.7pg/dL, and group III was 3492.7 ± 1.326.7pg/dL. The mean of histopathology renal score was also assessed, group I was 4.4 ± 0.52, group II was 8.6 ± 0.84, and group III was6.3 ± 1.70. Comparative test of serum cystatin C level, using ANOVA test and Benferroni post hoc test, in the treatment group has a p-value of > 0.05, it showed that there were no significant differences on the value of cystatin C level on the treatment group. In correlation test of renal histopathology score, suing Kruskal-Wallis test and Mann-Whitney post hoc test has a p-value of < 0.05, therefore there were significant differences on the mean value of renal histopathology score in the treatment group, with Eta correlation coefficient 0.847. Conclusion: The beneficial effects of breadfruit leaf extract can be attributed to its protective effects on renal cells damage. This treatment has an important role in reducing renal injury resulting from renal ischemia-reperfusion. However, breadfruit leaf extract did not significantly improve renal function based on serum cystatin C level.
CORRELATION BETWEEN MATERNAL AGE, LOW BIRTH WEIGHT, PREMATURITY AND HORMONAL DRUGS USING WITH THE OCCURRENCE OF HYPOSPADIAS (CASE STUDY AT BINA SEHAT JEMBER HOSPITAL, PARU JEMBER HOSPITAL, AND BHAYANGKARA BONDOWOSO HOSPITAL)
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.452

Abstract

Objective: This research aims to determine the correlation between maternal age during pregnancy, low birth weight (LBW), prematurity, and history of hormonal drugs used in the first trimester of pregnancy with the occurrence of hypospadias. Material & Methods: This research is an observational analytic research with case control design. The sample in this study were 50 samples that consisting of 25 patients with hypospadias and 25 patients without hypospadias at Bina Sehat Jember Hospital, Paru Jember Hospital, and Bhayangkara Bondowoso Hospital. After determined every case and control group, data acquired retrospectively by traced the hypospadias risk factors (maternal age at pregnancy, LBW, prematurity, and history of hormonal drugs using in the first trimester of pregnancy) by interviewing the patient's mother. The data of this research were analyzed by bivariate and multivariate using SPSS 16.0. Bivariate analysis in this study used chi-square Yates correction (chi-square with continuity correction) and fisher's exact test, whereas multivariate analysis used logistic regression techniques with significance p-value<0.05. Results: The result of bivariate analysis in this study showed that variable maternal age during pregnancy more than 35 years (p = 0.667) has no correlation with occurrence of hypospadias, while variable of LBW (p = 0.027), prematurity (p = 0.041), and the history of hormonal drug use in the first trimester of pregnancy (p = 0.049) have a correlation with the occurrence of hypospadias. Conclusion: In this study, there was a significant correlation between LBW, prematurity, and history of hormonal drugs using in the first trimester of pregnancy with the occurrence of hypospadias. This study did not show a significant correlation between maternal age during pregnancy with the occurrence of hypospadias.
MIRNA-92A PROFILING IN MUSCLE INVASIVE AND NON-MUSCLE INVASIVE BLADDER CANCERS IN RSUP DR SARDJITO YOGYAKARTA
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.472

Abstract

Objective: The purpose of this study was to determine the expression of miRNA-92A in Bladder Cancer can be used as a marker of tumor. Material & Methods: This study used a total of 30 samples. 15 samples of non-invasive bladder cancer and 15 samples of muscle invasive bladder cancer. The sample was obtained in the Anatomical Pathology laboratory from January 2016 to December 2016. Tumor tissue then extracted miRNA-92A with a RT-PCR examination with Total miRNA Mini Kit FavorPrepTM. The result is done by Mann Whitney U test. Results: The mean expression of miRNA-92A in non-muscle invasive bladder cancer is 12.75 while in muscle invasive bladder cancer had an average value of 31.79. The Mann Whitney U test was used to evaluate the median difference between these groups. There was a significant difference in the expression of miRNA-92A in both groups with P = 0.000 (<0.005). Conclusion: There is a significant difference between the expression of miRNA-92A in non-muscle invasive bladder cancer compared to muscle invasive bladder cancer with more dominant expression on muscle invasive bladder cancer
LAPAROSCOPIC PYELOLITHOTOMY AND Y-V PYELOPLASTY IN PATIENT WITH LARGE PYELUM CALCULI AND UPJO
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.529

Abstract

Objective: We report our experience in laparoscopic pyelolithotomy with Y-V pyeloplasty. Case(s) Presentation: A 35 years old man with a chief complained of right flank pain since 1 year ago and worsened since 3 months before admission. KUB-IVU showed right hydronephrosis, pyelum calculi, and UPJO. We performed Laparoscopic Pyelolithotomy and Y-V Pyeloplasty. Operative time was 180 minutes and blood loss was about 50 cc. Drain was removed at post-operative day 4. Operating wound was good, maximum VAS score was 3. Patient was discharged at post-operative day 4.Discussion: Y-V plasty technique significantly reduces surgery time and has lower risk of devascularization of the UPJ. The success of the Y-V plasty depends on proper placement of the incision ensuring a broad-based flap of pelvis. Following incision the apex of the flap is advanced and secured with an interrupted suture ensuring no tension. The remaining gaps are then closed in an interrupted fashion. Conclusion: Laparoscopic Pyelolithotomy for large stone with Y-V Pyeloplasty was safe and effective alternative treatment of large pyelum calculi and UPJO.
THE PREVALENCE OF KIDNEY FAILURE DUE TO URINARY CALCULI IN THE UROLOGY INPATIENT CARE DR. SOETOMO HOSPITAL FROM JANUARY 2016 TO DECEMBER 2017
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.558

Abstract

Objective: To know the profile of patients with kidney failure due to urinary calculi in the Urology Inpatient Care Soetomo General Hospital from January 2016 to December 2017. Material & Methods: a retrospective descriptive study was performed among 35 patients with kidney failure due to urinary tract stones. Individual patient data were obtained from the medical record. Results: The sex ratio known from the study between men and women was 60% : 40%. The age distribution was dominated by the patient within the range of 41-50 years old (38.14%) then followed by 51-60 and 31-70 years old (28.58% each), least found on <40 and >70 years old patient (2.86% each). Most of the urinary calculi were found in kidney (55.56%) then ureter (40%), and least found on urethra and bladder (2.22% each). Most types of renal failure found were Chronic Kidney Disease (48.57%), then Acute Kidney Injury (40%) then Acute Chronic Kidney Disease (11.43%). Conclusion: Chronic Kidney Disease was the most common type of renal failure found in the study compared to the other types such as Acute Kidney Injury and Acute on Chronic Kidney Disease. Calculus of kidney was the most frequent urinary calculi found. Men are more at risk of having kidney failure due to urinary calculi. 41-50 years old patients were found the most in this study.
URINALYSIS AS PREDICTOR OF UPPER-TRACT URINARY STONE ON COLIC PAIN PATIENTS: SINGLE-CENTER COHORT STUDY Wibowo, Edi; Satyagraha, Paksi; Daryanto, Besut
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.757

Abstract

Objective: There was no study in our country especially in our hospital that studied correlation between urinalysis and upper tract urinary stone on colic pain patients, so we conducted the study. Material & Methods: We_collected patients' data with colic abdomen from January 2018 to January 2020 then divided into hematuria and non-hematuria group respectively. We excluded patients with lower-tract urinary stones, DJ-stent insitu, BPH, and malignancy. All patients had urinalysis and abdominal ultrasound, then continued with non-contrast abdominal CT-Scan or Intravenous Urography. Retrospective and prospective cohort study was performed to collect data: age, sex, serum ureum and creatinine, urinalysis results (pH, specific gravity, nitric, leucocyte, erythrocyte, crystal, and bacteria), stone number, site, and size, then analysed the relationship between urinalysis results with upper-tract urinary stone incidence using point biserial correlation. Results: We found 235 colic patients, 115 and 120 patients in hematuria and non-hematuria group respectively. Male patients were higher, 137_(58.3%). The highest incidence was in the range 41-50 years-old_(30.6%), mean 46.5313,53 years-old. Stone incidence was 55.7% in all colic patients. Stone was proven 78.3% and 34.2% in hematuria and non-hematuria group respectively. There was significant association between upper-tract urinary stone and haematuria compared to non-haematuria patients (p<0.05). Relative-risk (RR) was 2.29, CI_95%. Conclusion: Hematuria increases two-folds probability of upper-tract urinary stone. It is necessary to expand population data and follow-up center to make this representative
URETHRAL INJURY AS A RARE COMPLICATION OF CIRCUMCISION: A CASE REPORT AND LITERATURE REVIEW Suwarno, Budi; Gumilar, Ogi Bahaurini; Rozidi, Achmad Romy Syahrial; Zharfan, Rahmat Sayyid
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.764

Abstract

Objective: In this report, we describe the case of urethral injuries after circumcision. Case(s) Presentation: A 5-year-old male came to the urology clinic complaining of urine seeping through the gauze-covered wound. The patient had undergone circumcision. Before the procedure, the patient could generally urinate through the external urethral orifice. His parent realized that the urine was flowing out through the circumcision scar instead of the external orifice. Even though the wound was open and wet, he felt painless when urinating. After cleaning the wound, it appeared that there was a sizeable chromic catgut thread knotted on the right corpus cavernosum. The pendular urethra was cut widely; therefore, the urine came out of this spot. A six French Foley catheter was inserted over the external urethral orifice, the cut urethra towards the bladder. The injured urethra was expected to be attached to simplify the next six-month operation by inserting this urinary catheter. Discussion: Urethral injury post circumcision is rarely reported, but this complication is dangerous due to its morbidity and long-term impact. The paradigm shift from two-stage repair to one-stage repair has developed. Mathieu’s modified technique and the Snodgrass technique are recommended. Conclusion: Urethral injury during circumcision can be devastating. The repair technique for urethral trauma depends on the involvement and condition of the surrounding soft tissue, also the size of the tissue damage.
THE EFFECT OF TURMERIC EXTRACT (CURCUMA LONGA) ADMINISTRATION IN KIDNEY HISTOPATHOLOGY FEATURES OF SPRAGUE DAWLEY RAT INDUCED BY 7,12-DIMETHYLBENZ(A)ANTHRACENE (DMBA)
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.775

Abstract

Objective: The purpose of this study was to understand the effect of turmeric extract (Curcuma longa) on the histopathology features of male Sprague-Dawley rat’s kidney induced with 7,12-Dimethylbenz(a)anthracene (DMBA). Material & Methods: This is an experimental design with post-test only control group design with 6 experimental groups and 30 samples. A comparison model was made by comparing the first group (K1) received no DMBA and the second group (K2) received DMBA alone. Four groups (K3, K4, K5, K6) received DMBA and different dosages of turmeric extract. The exposure was given for 14 days and histopathology features of the samples were assessed using the Gibson-Corley scoring system for Interstitial Tissue Damage. The data obtained was analyzed using One-sample Kolmogorov-Smirnov normality test and then analyzed with the Dunnett t-test. Results: The interstitial tissue damage in the negative control group (K1) and positive control group (K2/DMBA) was found to have a significant difference (p 0.000). There was no significant difference between DMBA only (K2) group and the group with turmeric administration groups (K3, K4, K5, K6) (P<0.05). Conclusion: DMBA can alter kidney histopathology features of male Sprague-Dawley rats. Administering turmeric (Curcuma longa) orally did not cause a change in kidney histopathology features of male Sprague-Dawley rats induced by DMBA.
ACTIVITY BASED COSTING METHOD IN DETERMINING UNIT COST OF LITHOTRIPSY FOR TREATMENT OF URINARY BLADDER CALCULUS AT VITA INSANI HOSPITAL PEMATANGSIANTAR Nasution, Muhammad Andriady Saidi; Girsang, Ermi; Nasution, Sri Lestari Ramadhani
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.783

Abstract

Objective: To determine the unit cost of lithotripsy for treatment of urinary bladder calculus at Vita Insani Hospital Pematangsiantar. Material & Methods: This study is a descriptive quantitative study, in which the data was obtained from the finance division of Vita Insani Hospital. The research object is the unit cost of accommodation that occurs in patients with urinary bladder calculus with lithotripsy cases from January 2020 to December 2020. Results: The unit cost of lithotripsy for urinary bladder calculus services at Vita Insani Hospital Pematangsiantar which is calculated using the activity-based costing (ABC) method is Rp 4.167.009. There is a difference in cost among the ABC method, hospital calculations, and INA CBG’s rates with the following details: the amount calculated for the hospital is Rp 4.996.718, while the calculation using ABC method is Rp 4.167.009; the difference in costs is Rp 829.709. INA CBG’s rates Rp 6.137.500, and compared to calculation of hospital, the difference cost is Rp 1.140.782. Compared to the INA CBG’s rates, to the unit cost of the ABC method, there is a difference, amounting Rp 1.970.491. Conclusion: The results of unit cost lithotripsy for treatment of urinary bladder calculus through the ABC method are lower compared to hospital calculation and INA CBG’s rates.
NECROTIZING FASCIITIS OF THE RIGHT FLANK MIMICKING A XANTHOGRANULOMATOUS PYELONEPHRITIS
Indonesian Journal of Urology Vol 29 No 2 (2022)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v29i2.785

Abstract

Objective: Xanthogranulomatous pyelonephritis (XGP) is a rare and serious chronic inflammation of the kidney, manifesting as a granulomatous inflammation of the kidney tissue. It can be life-threatening if not recognized and managed appropriately with antibiotics and surgery. Since there are no single pathognomonic clinical or radiological features, diagnosis requires combining the results of several clinical signs and imaging characteristics. However, determining the disease is oftentimes difficult as other conditions may mimic its characteristics, such as renal cancer, mesoblastic nephroma, renal abscess, and necrotizing fasciitis. Case(s) Presentation: A 45-year-old man was admitted to the emergency department of Soetomo General-Academic Hospital with right flank gangrene and fever for one week. Discussion: The patient was admitted to the hospital with sepsis and poor laboratory result. Computed Tomography (CT) scan results showed nephrolithiasis. The patient was diagnosed with Xanthogranulomatous pyelonephritis and underwent necrotomy in the Emergency Operating theatre. Conclusion: During the operation, necrotizing fasciitis was found in the right flank region instead. The external oblique muscle was intact without any tunneling into the retroperitoneal space. The postoperative care was joined by the Plastic Surgery department.

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