cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
jurnalrisetkimia@sci.unand.ac.id
Editorial Address
Department of Chemistry Faculty of Mathematics and Natural Sciences Universitas Andalas Kampus Universitas Andalas Limau Manih Padang 25163
Location
Kota padang,
Sumatera barat
INDONESIA
Jurnal Riset Kimia
Published by Universitas Andalas
ISSN : 1978628X     EISSN : 24768960     DOI : -
Core Subject : Science,
Chemistry
Arjuna Subject : -
Articles 562 Documents
 53   54   55   56   57 
Catechin-Rich Gambir (Uncaria gambir Roxb.) as a Nutraceutical Agent: Modulation of IL-10 Gene Expression and Cognitive Function in Elderly Rahmi Novita Yusuf; Eliza Arman; Lia Anggresani
Jurnal Riset Kimia Vol. 17 No. 1 (2026): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v17i1.938

Abstract

Aging is associated with increased oxidative stress and chronic inflammation, which contribute to cognitive decline. Modulation of anti-inflammatory pathways, particularly through interleukin-10 (IL-10), may offer a neuroprotective strategy. Catechins, polyphenolic compounds with antioxidant and anti-inflammatory properties, are abundant in Uncaria gambir Roxb., an Indonesian plant with high catechin content. This study aimed to evaluate the effects of catechin-rich gambir supplementation on cognitive function and IL-10 gene expression in older adults. A randomized, double-blind, placebo-controlled trial was conducted involving 58 participants aged ≥60 years with mild cognitive impairment (MoCA-Ina scores 20–25). Participants received either 224 mg/day of catechin or placebo for 12 weeks. Cognitive function was assessed using the MoCA-Ina, and IL-10 gene expression was measured using quantitative real-time PCR (qRT-PCR). Catechin supplementation significantly improved cognitive function compared to placebo (p < 0.001) and increased IL-10 gene expression after 12 weeks (p < 0.001). These findings suggest that gambir-derived catechins may contribute to cognitive improvement through modulation of anti-inflammatory pathways. However, further studies are required to confirm long-term effects and clinical applicability.
Extraction Of Indigo Dye From Strobilanthes cusia Leaves With Alkalization Process Using Sodium Hydroxide Riniati; Endang Widiastuti; Ari Marlina; Teguh Taufiqurohim
Jurnal Riset Kimia Vol. 17 No. 1 (2026): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v17i1.896

Abstract

This study explores the extraction of natural blue indigo pigment from Strobilanthes cusia leaves using a sequential process of anaerobic maceration and sodium hydroxide (NaOH) alkalization. Serving as a cleaner alternative to traditional quicklime (CaO) treatment, which deposits undesirable mineral residues on textiles, this method optimizes both extraction purity and pigment formulation. Fresh leaves were macerated anaerobically for three days to hydrolyze indican into indoxyl, followed by aeration and NaOH alkalization (pH 12) to facilitate oxidative coupling. The structural transformation was monitored via UV-Visible spectrophotometry, revealing a distinct shift from the precursor absorption (λmax) 291.94 nm to the indigo chromophore (λmax) 670.58 nm. Furthermore, Fourier Transform Infrared (FTIR) spectroscopy validated the indigotin molecular framework and confirmed that the NaOH-based route successfully circumvents the heavy calcium carbonate co-precipitation associated with conventional CaO extraction. To enhance physical handling, the purified extract was stabilized into a workable paste using maltodextrin. Colorimetric evaluations demonstrated that incorporating 5%, 10%, 15%, 20%, and 25% (w/v) maltodextrin provided optimal steric stabilization without impeding dye mass transfer into the cellulosic fibers, yielding excellent cycle-to-cycle dyeing reproducibility with total color differences (E*) maintained within the acceptable industrial tolerance ( 3). Ultimately, this sequential NaOH-maltodextrin approach provides a sustainable, residue-free, and highly efficient pathway for producing industry-ready natural indigo colorants.

Page 57 of 57 | Total Record : 562

 53   54   55   56   57 

Filter by Year

2007 2026


Reset
Filter By Issues
All Issue Vol. 17 No. 1 (2026): March Vol. 16 No. 2 (2025): September Vol. 16 No. 1 (2025): March Vol. 15 No. 2 (2024): September Vol. 15 No. 1 (2024): March Vol. 14 No. 2 (2023): September Vol. 14 No. 1 (2023): March Vol. 13 No. 2 (2022): September Vol. 13 No. 1 (2022): March Vol 13, No 1 (2022): March Vol. 12 No. 2 (2021): September Vol 12, No 2 (2021): September Vol 12, No 1 (2021): March Vol. 12 No. 1 (2021): March Vol. 11 No. 2 (2020): September Vol 11, No 2 (2020): September Vol. 11 No. 1 (2020): March Vol 11, No 1 (2020): March Vol 10, No 2 (2019): September Vol. 10 No. 2 (2019): September Vol 10, No 1 (2019): March Vol. 10 No. 1 (2019): March Vol 10, No 1 (2019): March Vol. 9 No. 2 (2016): March Vol 9, No 2 (2016): March Vol 9, No 1 (2015): September Vol. 9 No. 1 (2015): September Vol. 8 No. 2 (2015): March Vol 8, No 2 (2015): March Vol 7, No 2 (2014): March Vol. 7 No. 2 (2014): March Vol 5, No 2 (2012): March Vol. 5 No. 2 (2012): March Vol 5, No 1 (2011): September Vol. 5 No. 1 (2011): September Vol. 4 No. 2 (2011): March Vol 4, No 2 (2011): March Vol. 4 No. 1 (2010): September Vol 4, No 1 (2010): September Vol 3, No 2 (2010): March Vol. 3 No. 2 (2010): March Vol 3, No 1 (2009): September Vol. 3 No. 1 (2009): September Vol. 2 No. 2 (2009): March Vol 2, No 2 (2009): March Vol 2, No 1 (2008): September Vol. 2 No. 1 (2008): September Vol. 1 No. 2 (2008): March Vol 1, No 2 (2008): March Vol. 1 No. 1 (2007): September Vol 1, No 1 (2007): September More Issue