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Biology, Medicine, & Natural Product Chemistry

BIOMEDICH
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Published by Universitas Islam Negeri Sunan Kalijaga Yogyakarta

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Core Subject : Health, Science,

Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Public Health

BIOLOGY, MEDICINE, & NATURAL PRODUCT CHEMISTRY, this journal is published to attract and disseminate innovative and expert findings in the fields of plant, animal, and microorganism secondary metabolite, and also the effect of natural product on biological system as a reference source for researchers in these fields, and with the aim to set international standards in their methodology.

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Articles 5 Documents

Search results for , issue "Vol 6, No 2 (2017)" : 5 Documents clear

On Designing Interactive Online Atlas of Reptile Anatomy (Mabouya multifacsiata) Muhammad Jafar Luthfi; Riyanto Riyanto
Biology, Medicine, & Natural Product Chemistry Vol 6, No 2 (2017)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

This research is an integration between fields of Biology, Photography, Design, and Informatics Engineering. The study aimed to build an interactive online atlas of reptile anatomy to improve the accessibility and data sharing (free access) of reptile anatomy. Website was developed using SDLC (System Development Life Cycle) which consist of five steps as follows: website’s strategic planning, determine the scope of website, website’s requirements analysis, design and implementations of website, and testing. Based on the results of testing and system implementation, it can be concluded that online interactive atlas (AtlasAnatomy.org) had been successfully built as anatomical educational media of reptile.

The Female Population Growth Projection Year 2021 in Trenggalek Regency by Leslie Matrix Model on the Birth Rate and Life Expectancy Dewi Anggreini
Biology, Medicine, & Natural Product Chemistry Vol 6, No 2 (2017)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

This research aims to determine the number of female residents in Trenggalek Regency in 2021 based on data on birth rate and life expectancy. The use of eigenvalues and eigenvectors aims to determine the dividing age distribution by Leslie matrix model. The eigenvectors are used to determine the number of female populations of each age interval, while the eigenvalues are used to determine population growth rates. The research method used is to determine the subject of research. The next stage is to collect research data, then analyze the data and last draw conclusions. The research data is obtained from BPS Kabupaten Trenggalek and BPS East Java Province that is data of woman population from year 2010-2015. The result of this research using Leslie matrix model for female population in Trenggalek Regency that is discrete model. The discrete model is divided into fourteen age intervals constructed using the birthrate and life expectancy. The conclusions of the study showed that the number of female population in Trenggalek Regency tended to increase with positive eigen value greater than one. In other words, the growth rate of female population in Trenggalek Regency tends to be positive. The success of Leslie's matrix model is the application of case studies in predicting the number of female populations in Trenggalek District by 2021 using the MAPLE 16 Program.

Clustering of 18 Local Black Rice Base on Total Anthocyanin Kristamtini Kristamtini; Endang Wisnu Wiranti
Biology, Medicine, & Natural Product Chemistry Vol 6, No 2 (2017)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Black rice has a high anthocyanin content in the pericarp layer, which provides a dark purple color. Anthocyanin serve as an antioxidant that control cholesterol level in the blood, prevent anemia, potentially improve the body's resistance to disease, improve damage to liver cells (hepatitis and chirrosis), prevent impaired kidney function, prevent cancer/tumors, slows down antiaging, and prevent atherosclerosis and cardiovascular disease. Exploration results at AIAT Yogyakarta, Indonesia from 2011 to 2014 obtained 18 cultivar of local black rice Indonesia. The names of the rice are related to the color (black, red or purple) formed by anthocyanin deposits in the pericarp layer, seed coat or aleuron. The objective of the study was to classify several types of local black rice from explorations based on the total anthocyanin content. The study was conducted by clustering analyzing the total anthocyanin content of 18 local black rice cultivars in Indonesia. Cluster analysis of total anthocyanin content were done using SAS ver. 9.2. Clustering dendogram shows that there were 4 groups of black rice cultivars based on the total anthocyanin content. Group I consists of Melik black rice, Patalan black rice, Yunianto black rice, Muharjo black rice, Ngatijo black rice, short life of Tugiyo black rice, Andel hitam 1, Jlitheng, and Sragen black rice. Group II consists of Pari ireng, Magelang black hairy rice, Banjarnegara-Wonosobo black rice, and Banjarnegara black rice. Group III consists of NTT black rice, Magelang non hairy black rice, Sembada hitam, and longevity Tugiyo black rice. Group IV consist only one type of black rice namely Cempo ireng. The grouping result indicate the existence of duplicate names among the black rice namely Patalan with Yunianto black rice, and short life Tugiyo with Andel hitam 1 black rice.

Vitamin C and Total Sugar Content Characterization on 31 Accessions of Banana Collection of Banana Germplasm Plants of Yogyakarta Indrasari, Siti Dewi; Kristamtini, Kristamtini; Wiranti, Endang Wisnu
Biology, Medicine, & Natural Product Chemistry Vol 6, No 2 (2017)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Banana is one of the tropical fruits that people like because it tastes good and contains good nutritional value that beneficial for health.Ã‚Â The content of vitamin C and total sugar are an important character to complete the morphological characterization of banana accession that can be utilized by breeders in choosing accession as parent. The study aimed to determine the content of vitamin C and total sugar on 31 accessions of banana collection of Banana Germplasm Plants of Yogyakarta. The research was conducted at Banana Germplasm Plantation and Laboratory of Agricultural Technology Production of Gadjah Mada University, Yogyakarta from January to December 2016. The results indicated that 31 banana accessions showed their susceptibility to vitamin C content 60.42 + 39.22 mg / 100 g and total sugar 22.06 + 16.01%. High standard deviation values indicate the large diversity of banana accessions that were characterized, indicating that the accessions of each characterized banana were separate accessions of one another.

Alliin as a Natural Bioactive from Single Bulb Garlic (Allium sativum) for Nitric Oxide (NO) Increasing in Atherosclerotic Process Based on Insilico Screening Riza Rahayu Ilmawati; Ahya Zhilalikbar Amin; Mohamad Amin
Biology, Medicine, & Natural Product Chemistry Vol 6, No 2 (2017)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Atherosclerosis is a chronic inflammatory disease in the arterial wall mediated by proinflammatory factor. Atherosclerosis cause heart disease and stroke is generally believed to be preventable. The single bulb garlic is one of the local plants known as the medicinal plant in Indonesia. Garlic contains alliin compounds as antiatherosclerotic agent. This study aimed to determine the potential of active compound of single bulb garlic as an antioxidant that improve endothelial function by increasing nitric oxide (NO) to increase vasodilation. The bioinformatics webserver used in this study are: Pubchem, Pharmmapper, Swiss Target Prediction, Superpred, Uniprot, and Protein Data Bank. Docking software using PyRx, PyMOL and Discovery Studio. Based on these steps, it was found that alliin interacts with nitric oxide synthase (NOS) through hydrogen and alkyl bonds. Alliin is effective as an inhibitor of NOS based on binding afinity (-5.4 kcal / mol) although no more negative than an aspirin inhibitor based on binding afinity (-6.5 kcal / mol). Based on the docking results, it is found that alliin is effective as a potential drug to decreased atherosclerosis.

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