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Mutiara Medika: Jurnal Kedokteran dan Kesehatan
Published by Universitas Muhammadiyah Yogyakarta
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Health Professions Medicine & Pharmacology
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 2 Documents
 1 
Search results for , issue " Vol 8, No 1 (s) (2008)" : 2 Documents clear
Efek Penggunaan Minyak Kelapa Murni yang Beredar di Pasaran terhadap Nafsu Makan Tikus (Rattus norvegicus Belinda, Febri Akhmad; Makiyah, Sri Nabawiyati Nurul
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 1 (s) (2008)
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Recently, obesity being public ’s enemy which makes people try to against it effectively, one of the way is by consuming virgin coconut oil to press on appetite. Whether virgin coconut oil can press on rat ’s appetite, needs to be studied. Objectives of this research is to determine effect of market products of virgin coconut oil related to white rat appetite Design of this research is an experimental research in vivo on animal test which uses 20 rats winstar strain 2 months age, 138-212 gram body weight as subject. Rats divided into 4 groups; 3 groups as treatment and 1 group as control. Treatment group given virgin coconut oil from 3 different products per oral in 30 days in converse dosage of human 50cc/hari x 0,018 x rats bodyweight /200 gr. Then measuring the bodyweight each 5 days and measuring the pigswill everyday in 30 days. Result of this research showed that the bodyweight in totally and specially the feed intake in treatment groups lower than control group. It could concluded that virgin coconut oil can decrease the appetite of white rat (Rattus norvegicus) which can be measured from the bodyweight in totally and specially the feed intake.Akhir-akhir ini obesitas menj adi musuh masyarakat, dimana kemudian masyarakat berlomba- lomba untuk melawannya dengan berbagai cara, salah satunya dengan mengkonsumsi minyak kelapa murni untuk menekan nafsu makan. Apakah minyak kelapa murni dapat menekan nafsu makan pada tikus putih perlu diteliti. Tujuan penelitian ini adalah untuk mengetahui efek penggunaan minyak kelapa murni (VCO) yang beredar di pasaran Desain penelitian adalah eksperimental laboratori in vivo pada hewan uj i, menggunakan 20 ekor tikus putih (Rattus norvegicus) galur Wistar usia ± 2 bulan dengan berat antara 138-212 gram. Dibagi menjadi 4 kelompok dengan 3 kelompok perlakuan dan 1 kelompok kontrol. Kelompok perlakuan diasup minyak kelapa murni dengan 3 merek berbeda per oral setiap hari selama 30 hari dengan dosis konversi dari manusia 50cc/hari x 0,018 x berat badan tikus/ 200 gr. kemudian ditimbang berat badannya tiap 5 hari sekali dan ditimbang sisa pakannya setiap hari. Setelah 30 hari kemudian dianalisa. Hasil penelitian menunjukkan bahwa tikus yang diberi perlakuan dengan minyak kelapa murni mempunyai intake pakan dan berat badan lebih rendah dibandingkan dengan kelompok kontrol. Dapat disimpulkan bahwa minyak kelapa murni dapat menurunkan nafsu makan tikus putih (Rattus norvegicus) diukur dari intake pakan dan berat badan secara menyeluruh.
Efektivitas Antibakteri Infusa Kunyit Asam dan Jamu Kemasan terhadap Kuman Penyebab Diare secara In Vitro Suryani, Lilis; Kusumaningsih, Eva
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 1 (s) (2008)
Publisher : Universitas Muhammadiyah Yogyakarta

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Abstract

Most people consume liquid herbal medicine known as kunyit asam and powder (package) herbal medicine that contains guava leaf extract (Psidii folium), tumeric rhizome (Curcuma domesticate rhizome), jali seeds (Coicis Semen), mojokeling fruit (Chebulae fructus), pomegranate peel (Granati Pericarpium). Those ingredients had been known to treat dysentery and chronic diarrhea, because containing tanin, astringent, flavonoid, fenol, alkaloid, atsiri oil, and vitamin C. This research is done to know the antibacterial effectiveness of kunyit asam infusion and herbal package medicine to various germ of diarrhea cause, like Escherichia coli, Shigella Dysenteriae, and Vibrio cholerae. The antibacterial activity determined by amount MIC and MBC applying Tube Dilution Method. The research bacterials are Escherichia coli strain ATCC 25922, Shigella Dysenteriae 2a 1992/2/Belgia, Vibrio Cholerae 011986/1/2/Belgia. The result of research of antibacterial effectiveness show us that kunyit asam infusion unable to inhibit and kill the Escherichia coli by MIC and MBC > 75 gr%. While kunyit asam infusion able to inhibit and kill the Shigella dysenteriae by MIC and MBC 4,3 gr% and 5,5 gr%, Vibrio Cholerae by MIC and MBC 1,4 gr% and 2,734 gr%. Herbal package medicine able to inhibit Escherichia coli by MIC 30 gr%, Shigella Dysenteriae by MIC and MBC 15 gr% and 30 gr%, Vibrio Cholerae by MIC andMBC 0,003 gr% and 0,004gr%. The conclusion from the result of the research were the infusion of kunyit asam and herbal package medicine. Efective to kill the Shigella dysenteriae and Vibrio cholerae, but there is no antibacterial effect to Escherichia coli.Masyarakat sering mengkonsumsi jamu kunyit asam sertajamu kemasan yang mengandung ekstrak daun jambu biji (Psidii folium), rimpang kunyit (Curcumadomesticate rhizome), biji jali (CoicisSemen), Buah mojokeling (Chebulae fructus), kulit buah delima (GranatiPericarpium). Bahan ini sudah lama dikenal untuk mengobati penyakit disentri dan diare kronik, karena mengandung tanin, astringent, flavonoid, fenol, alkaloid, minyak astiri, dan vitamin C. Penelitian ini dilakukan untuk mengetahui efektivitas antibakteri infusa kunyit asam dan jamu kemasan terhadap berbagai kuman penyebab diare, seperti Escherichia coli, Shigella dysenteriae, dan Vibrio cholerae. Aktivitas antibakteri ditentukan dengan menghitung Kadar Hambat Minimal (KHM) dan Kadar Bunuh Minimal (KBM) dengan metode seri pengenceran tabung (Tube Dilution Method). Bakteri uji yang digunakan meliputi Escherichia coli strain ATCC 25922, Shigella dysenteriae 2a 1992/2/Belgia, Vibrio cholerae 01 1986/1/2/Belgia. Hasil penelitian efektivitas antibakteri menunjukan bahwa infusa kunyit asam tidak mampu menghambat dan membunuh Escherichia coli dengan KHM dan KBM > 75 gr%. Infusa kunyit asam mampu menghambat dan membunuh Shigella dysenteriae dengan KHM dan KBM 4,3 gr% dan 5,5 gr%, Vibrio cholerae dengan KHM dan KBM 1,4 gr% dan 2,734 gr%. Jamu kemasan mampu menghambat Escherichia coli dengan KHM 30 gr%, Shigella dysenteriae dengan KHM dan KBM sebesar 15 gr% dan 30 gr%, Vibrio cholerae dengan KHM dan KBM sebesar 0,003 gr% dan 0,004 gr%. Dapat disimpulkan bahwa infusa kunyit asam dan jamu kemasan efektif membunuh Shigella dysenteriae dan Vibrio cholerae, tidak punya efek antibakteri terhadap Escherichia coli.

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