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INDONESIA
INDONESIAN JOURNAL OF PHARMACY
Published by Universitas Gadjah Mada
ISSN : 23389427     EISSN : 23389486     DOI : -
Core Subject : Health,
Medicine & Pharmacology
Indonesian Journal of Pharmacy (ISSN-e: 2338-9486, ISSN-p: 2338-9427), formerly Majalah Farmasi Indonesia (ISSN: 0126-1037). The journal had been established in 1972, and online publication was begun in 2008. Since 2012, the journal has been published in English by Faculty of Pharmacy Universitas Gadjah Mada (UGM) Yogyakarta Indonesia in collaboration with IAI (Ikatan Apoteker Indonesia or Indonesian Pharmacist Association) and only receives manuscripts in English. Indonesian Journal of Pharmacy is Accredited by Directorate General of Higher Education (DGHE) DIKTI No. 58/DIKTI/Kep/2013.
Arjuna Subject : -
Articles 3 Documents
 1 
Search results for , issue " Vol 12 No 4, 2001" : 3 Documents clear
THE USE OF GENERIC DRUGS IN PHARMACY IN THE MUNICIPALITY OF YOGYAKARTA DURING MONETARY CRISIS (OBSERVATION ON MARCH 1997 - MARCH 1998) Andari, Irin Dwi; Wahyono, Djoko
INDONESIAN JOURNAL OF PHARMACY Vol 12 No 4, 2001
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.501 KB) | DOI: 10.14499/indonesianjpharm0iss0pp12-20

Abstract

Monetary crisis that strike Indonesia had also impacts on health services either private or public services, including pharmaceutical industries. The industries had difficulty to find raw materials for production which in turn resulting in scarce and the rise of drug price. The situation could urged the patients to shift of using the patented medicines into generic ones which are relatively cheaper. The present study has therefore aimed to observe the usage of generic products before (March 1997 - August 1997) and during (September 1997 - March 1998) the monetary crisis periods in five pharmacies of Yogyakarta Municipality. The data were taken from the stocks units and from doctor’s prescriptions, which were then analyzed by ANAVA (p=0,5). Other data were also collected and analyzed descriptively from questionnaires requested to the a hundred of pharmacy’s visitors at the same periods as above.The results have shown that the number of generic product usage was not different between the two periods, except amoxycillin 500 mg, antalgin, dextrometorphan, captopril 25 mg, and glibenclamide tablets. The respondents have revealed that they have information on generic products (91%) from mostly mass media (44%). As many as 39 % of them assume that the generic products are cheaper than of patented products and it has the same effect.Key words : monetary crisis, generic product, pharmacies
A BIOEQUIVALENCE STUDY OF AMPICILLIN (GENERIC PRODUCTS) IN RABBITS Wahyono, Djoko; ., Nurlaila
INDONESIAN JOURNAL OF PHARMACY Vol 12 No 4, 2001
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (208.809 KB) | DOI: 10.14499/indonesianjpharm0iss0pp198-204

Abstract

The use of generic medicine in health services has strongly been suggested by government. Production of those type of medicine by government appointed pharmaceutical manufacturers has shown a good progress. However, monitoring to those products in the market, based on the bioequivalence quality, still need to be improved. An example of medicine produced in generic form is Ampicillin, one of the broad spectrum antibiotic effective to treat upper respiratory tract infections. The aim of this research was to evaluate the bioavailability of generic ampicillin capsules (500 mg) compared to the patented product. The research was carried out as follow: six male rabbits weighing 2.0 - 2.5 kg were assigned to a cross - over design to receive both products orally after 24 hour fasting. The generic and patented products were given to the rabbits with a week wash-out period. Following drug administration, the blood samples (11 samples) were drawn from the marginal ear vein at designated time (5-330 minutes) to analyse unmetabolized ampicillin fluorometrically. Detection of the ampicillin was recorded at maximum excitation (350 nm) and maximum emission (420 nm) wavelengths. The result showed that the AUC value of the generic product (3,211.25 ± 635.23 g hour/ml) was significantly higher than that of patented product (2,425.68 ± 895.26 g hour/ml) (p<0.05). The peak level of ampicillin (Cmax) was significantly higher for the generic (17.00 ± 5.10 g/ml) than patented product (11.25 ± 2.75 g/ml), while time to reach Cmax was not significantly different between the two products, ie. 77.34 ± 16.70 minutes (generic) and 82.48 ± 13.57 minutes (patented). The study concluded that the ampicillin capsules in generic form had a better biovailability than patented product. Key words: ampicillin, generic product, bioequivalence
THE INFLUENCE OF DRUG INFORMATION ON DRUG SELECTION AND USAGE COUGH PREPARATION AT SELF MEDICATION IN GODEAN SUBDISTRICT ., Satibi
INDONESIAN JOURNAL OF PHARMACY Vol 12 No 4, 2001
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (105.187 KB) | DOI: 10.14499/indonesianjpharm0iss0pp194-197

Abstract

The influence of drug information on drug selection and usage cough preparation for self medication in Godean was investigated. The study was performed in Godean community by distributing questioner to respondences. Stratified random sampling followed by equal sampling were used to select subjects. Multiple regression and t-test were used to analyzed the result statistically. The result showed that drug information influences drug selection and usage (Z1/2 = 0,050). Key words : Self medication, information, cough medicine

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