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Journal of Islamic Pharmacy
Published by Universitas Islam Negeri Maulana Malik Ibrahim Malang
ISSN : 24605182     EISSN : 25276123     DOI : http://dx.doi.org/10.18860/jip
Core Subject : Health, Science,
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health
Welcome to Journal of Islamic Pharmacy (e-ISSN : 2527-6123) formerly Jurnal Farmasains (p-ISSN : 2460-5182) Department of Pharmacy, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Indonesia. The journal was established in 2015 and online publication was begun in 2016. Since 2016, the journal has been published in English and only receives manuscripts in English.
Arjuna Subject : Pharmacology, Toxicology and Pharmaceutics - Pharmacology, Toxicology and Pharmaceutics (Lain-Lain)
Articles 5 Documents
 1 
Search results for , issue "Vol 4, No 2 (2019): J. Islamic Pharm." : 5 Documents clear
The Role of Substance P in Chronic Low Back Pain (CLBP) Rachmawati, Yusnita
Journal of Islamic Pharmacy Vol 4, No 2 (2019): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v4i2.8163

Abstract

Low Back Pain is one of the disease that causing global disability in the worldwide. In the past 10 years, prevalence of LBP has not decreased, it makes global burden increase substantially. Chronic low back pain(CLBP) is pain that is almost experienced daily by patients in the lower back region in a period of more than 3 months. Chronic low back pain is a mixture of pain that arises through nociceptive and neuropathic mechanisms. Over the past decade, numerous  guidelines have been used  in the management of CLBP. Problems that are still a controversy include the management of pain. The mechanism of many treatment measures is still in the low to moderate effectiveness stage, so that the pain management target is not optimal. Substance P is a neuropeptide that release  both in acute and chronic pain. Therefore study about mechanisms that affect SP release may show important information regarding pathological alterations in pain perception.
Tricyclic Antidepressants in Chronic Low Back Pain : A Review Ilmanita, Dzikrina; Hidayati, Hanik Badriyah
Journal of Islamic Pharmacy Vol 4, No 2 (2019): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v4i2.8217

Abstract

Chronic low back pain (LBP) is the frequent chronic pain and notable health problem which is the main reason of disabling conditions, individual suffering, sick leave, and costly treatment.  Unfortunately, available therapy especially oral medicines only beneficial in no more than 50% of patients. Tricyclic antidepressants (TCAs) are commonly used for neuropathic pain but the data for neuropathic LBP is limited. The purpose of this review is to evaluate the efficacy and adverse drug reaction of TCAs in chronic LBP. We searched scientific search engines including Scopus and PubMed and collected original articles including Randomized Clinical Trial (RCT), comparative, and observational study about Tricyclic Antidepressants treatment in chronic LBP from 1998 to 2019. In this review, 5 articles and 543 patients were evaluated. All recruited articles are randomized clinical trials. Among all five relevant articles, three of them evaluate amitriptyline treatment in chronic LBP while the rest articles evaluate imipramine and nortriptyline. Amitriptyline is the most well-studied TCA for chronic LBP. We found that both amitriptyline and nortriptyline can reduce pain severity significantly when the dose is increased gradually depending on patient tolerance. TCAs can also improve disability significantly. However, single-dose imipramine is not superior than placebo. We conclude that TCAs can be effective for treating chronic LBP when used routinely for several weeks and the dose should be increased gradually depending on patient tolerance although further studies are required to confirm the optimal dose for analgesia. The most prevalence Adverse Drug Reactions (ADRs) of TCA including dry mouth, somnolence, insomnia, sedation, and constipation.
Pengaruh Variasi Konsentrasi Propilen Glikol Sebagai Enhancer Terhadap Sediaan Transdermal Patch Ibuprofen In Vitro Misnamayanti, Misnamayanti; Sugihantoro, Hajar; Fauziyah, Begum
Journal of Islamic Pharmacy Vol 4, No 2 (2019): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v4i2.8029

Abstract

Ibuprofen is an anti-inflammatory class of non-steroidal propionic acid used in the treatment of osteoarthritis, analgesics, and antipyretics. Ibuprofen made in a transdermal patch to avoid side effects of irritation to the stomach, first pass effect on application oral. This aims of the research to determine the physical characteristics of the patch, the effect of propylene glycol concentration (150 mg, 200 mg, 250 mg) on the thickness patch, pH, and the rate of penetration as increase in penetration of the ibuprofen transdermal patch. Patch preparations were made in 3 draft formulas with varying concentrations of propylene glycol 150 mg, 200 mg, and 250 mg. The method used for penetration testing is Franz diffusion cells. The results of physical characteristics are clear, odorless, dry, not cracked, 300 folds, thickness ranges from 0.142 to 0.184. The concentration of propylene glycol effects (p-value 0.05) the penetration and no effect (p-value 0.05) the pH test. Increasing the concentration of propylene glycol causes an increase medicine that penetrate the skin.Keywords: Ibuprofen, transdermal patch, propylene glycol
Analisis Kriteria Sistem Jaminan Halal pada Produksi Susu di PT. Greenfields Indonesia Tahun 2019 Hartina, Siti; Syahrir, Achmad; Atmaja, Ria Ramadhani Dwi
Journal of Islamic Pharmacy Vol 4, No 2 (2019): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v4i2.8087

Abstract

World demand for halal pharmaceutical products, which include food, cosmetics, drugs, and other products will continue to grow with the increasing of global Moslems population in the world. Milk is one of the pharmaceutical products produced from livestock commodities. It is processed into 2 types of products namely ESL and UHT milk. In Indonesia, the halal status of a product is a crucial point for consumers who are predominantly by Moslems. In its processing, Indonesian Ulema Council (MUI) has a rule called HAS 23101, a halal certification requirement as an implementation of Halal Guarantee System. This study examines the importance of the Halal Assurance System criteria in milk production in the Indonesian food industry. The purpose of this study is to analyse the suitability of the halal guarantee system criteria for milk production in PT. Greenfields Indonesia based on HAS 23101 standards. This research is a descriptive observational study. The data collection process is carried out by providing a checklist to the halal management team in the food industry. The results obtained are the percentage of conformity to the 100% Halal Policy, 100% Halal Management Team, 100% Training and Education, 100% Material, 100% Product, 91.6% Product Facility, Written Procedure for Critical Activity 100%, 100% Search Capability, Products that do not meet 77.8% criteria, 100% internal audit, and 100% management review. The percentage of conformity results obtained as a whole was 97.2%.
Description of Knowledge and Attitude of Prospective Hajj Pilgrims KBIH Mandiri 2019 in Malang City About Hypertension riskiyah, riskiyah
Journal of Islamic Pharmacy Vol 4, No 2 (2019): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v4i2.8083

Abstract

ABSTRACTHypertension is one of the diseases that can cause people’s death and it usually does not give any symptoms. Hypertension often occurs to the pilgrims. Knowledge and proper attitudes about hypertension of prospective pilgrims from Indonesia, especially in Malang city (East Java), are expected to reduce morbidity and mortality rates because they can manage their illness, properly. The purpose of this study is to describe the level of hypertension-related knowledge and attitudes of prospective pilgrims from KBHI 2019. The method used in this study is a descriptive cross-sectional study. 48 participants have participated in this study. They are the 2019 pilgrims from Indonesia. The results showed that 18 people (38%) had good knowledge about hypertension, 17 people (35%) are intermediately educated and 13 people (27 %) are lack of knowledge. Furthermore, this study has indicated that 25 people (52%) have positive attitudes and 23 people (48%) have negative attitudes about hypertension. This study concluded that in the majority, the 2019 prospective pilgrims from Malang have good knowledge and acceptable attitudes about hypertension.Keywords: Hajj pilgrims, hypertension, knowledge, attitude 

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