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Systematic Review: Mechanism of Ginger (Zingiber offinale) as Anti-inflammatory Dwi Monika Ningrum; Denih Agus Setia Permana; Atri Sri Ulandari
Journal of Pharmaceutical and Natural Resources Vol. 1 No. 1 (2025): Journal of Pharmaceutical and Natural Resources
Publisher : Jurusan Farmasi Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpnar.v1i1.pp20-23

Abstract

The appearance of inflammation is a hallmark of a large number of human diseases, ranging from infection to neurodegeneration. In the treatment of inflammation, a group of drugs that are widely given are non-steroidal anti-inflammatory drugs (NSAIDs). Long-term use of NSAIDs can result in various side effects, namely gastrointestinal disorders, damage to the kidneys, and cardiovascular disorders. Given the side effects that can be caused by the use of NSAIDs, other alternatives are needed to overcome and reduce inflammation. One of the plants that can be used to treat inflammation is ginger. This journal review was conducted by reviewing electronic journals related to the use of ginger as an anti-inflammatory mechanism with the study report method. The inclusion criteria used include ginger as an anti-inflammatory, journals from 2008-2012, journals are scientific journals, in vitro and in vivo, free full text, while the exclusion criteria are the benefits of ginger not as an anti-inflammatory. Ginger as an anti-inflammatory has several mechanisms including inhibiting macrophage activation, increasing endogenous antioxidant activity, inhibiting the production of PGE2, tumor necrosis factor α (TNFα), and cyclooxygenase. Inhibition of cyclooxygenase is selective only for COX-2 activity. COX-1 inhibition is associated with gastrointestinal irritation, selective inhibition of COX-2 will help minimize side effects.
Edukasi pencegahan anemia pada remaja putri di MAN 2 Semarang Sulistyianingsih Sulistyianingsih; Indiana Gita Anggraeni; Dwi Monika Ningrum
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 10, No 2 (2026): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v10i2.38944

Abstract

Abstrak Anemia merupakan persoalan kesehatan yang prevalen di kalangan remaja putri dan berisiko menghambat konsentrasi belajar, kebugaran, serta kesehatan reproduksi di masa depan. Minimnya literasi mengenai anemia menjadi salah satu faktor determinan yang meningkatkan risiko kejadian tersebut pada kelompok usia remaja. Kegiatan ini bertujuan untuk mengoptimalisasi pemahaman siswi di MAN 2 Semarang terkait pencegahan anemia melalui pendekatan promotif. Metode yang diterapkan meliputi pemaparan materi, penayangan video edukasi, diskusi interaktif, serta pendistribusian selebaran (leaflet). Efektivitas program diukur menggunakan instrumen kuesioner sebelum (pre-test) dan sesudah (post-test) kegiatan. Melibatkan 80 partisipan, profil usia didominasi oleh remaja 16 tahun (41,25%), diikuti 15 tahun (35%), 17 tahun (13,75%), dan 18 tahun (10%). Hasil evaluasi menunjukkan bahwa pada tahap awal, 72,5% responden berkategori baik dan 27,5% berkategori kurang. Namun, pasca-intervensi, seluruh responden (100%) berhasil mencapai kategori pengetahuan baik. Temuan ini menegaskan bahwa edukasi kesehatan berbasis sekolah sangat efektif dalam memperkuat literasi remaja mengenai pencegahan anemia. Kata kunci: anemia; edukasi kesehatan; remaja putri; pengetahuan; pencegahan anemia. Abstract      Anemia is a prevalent health problem among adolescent girls and poses a risk of hindering concentration in learning, fitness, and reproductive health in the future. Lack of literacy regarding anemia is a determining factor that increases the risk of this incident in the adolescent age group. This activity aims to optimize the understanding of female students at MAN 2 Semarang regarding anemia prevention through a promotive approach. The methods applied include material presentation, educational video screenings, interactive discussions, and leaflet distribution. The program's effectiveness was measured using a questionnaire instrument before (pre-test) and after (post-test) the activity. Involving 80 participants, the age profile was dominated by 16-year-olds (41.25%), followed by 15-year-olds (35%), 17-year-olds (13.75%), and 18-year-olds (10%). The evaluation results showed that in the initial stage, 72.5% of respondents were categorized as good and 27.5% were categorized as poor. However, after the intervention, all respondents (100%) managed to achieve the good knowledge category. These findings confirm that school-based health education is highly effective in strengthening adolescent literacy regarding anemia prevention.. Keywords: anemia; health education; adolescent girls; knowledge; anemia prevention.