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All Journal African Multidisciplinary Journal of Sciences and Artificial Intelligence Open Access DRIVERset African Journal of Biochemistry and Molecular Biology Research Open Access DRIVERset African Journal of Sciences and Traditional Medicine Open Access DRIVERset Kwaghe International Journal of Sciences and Technology Open Access DRIVERset African Journal of Clinical Medicine and Pharmacy Research African Journal of Medicine, Surgery and Public Health Research
Oteng, Joseph
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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Practice and Determinants of Breast Self-Examination Among Women in Chereponi District, Northern Region of Ghana Oteng, Joseph
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 2 No 1 (2025): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v2i1.4856

Abstract

Breast cancer is a public health problem in Ghana and early detection is a key determinant to the survival rate of the disease. It is a preventive measure usually encouraged among women to examine their breasts by feeling them several times a month for any lumpiness or hardness. The study was conducted to find out the practice and determinants of BSE among women in the Chereponi district in the northern region of Ghana. Method: A community-based cross-sectional research design with a mixed methods approach was utilized among 384 women aged 18 - 49 years in the Chereponi district. Participants were recruited using a multistage sampling technique with a structured questionnaire and Key Informant Interviews for data collection. The descriptive and inferential data were analysed using the SPSS and NVIVO. Results: The finding reveals that the participants were abreast with Breast self-examination (BSE) techniques. The bivariate correlation study of the level of knowledge and BSE also indicated strong positive relationship between the two variables. In other words, a two-tailed Pearson correlation coefficient of 0.777 shows positive significant relationship between the two variables at 0.01 level. Conclusion: The practice of BSE was found to have a direct relationship with the knowledge. Though the practice was commendable among those who had the knowledge, there were still challenges of cultural and social norms that mitigated against the practice of breast self-examination. It is important to empower women, promote supportive relationships and maximise women’s social networks to promote BSE uptake at the community level.
Effect of Jatropha Gossypiifolia Leaves in Wistar Albino Rats Against Gentamicin-Induced Biochemical Injury Umaru, Isaac John; Akafa, Tensaba Andes; Oteng, Joseph; Akem, Ingwu Joseph; Ngbede, Ocheifa Mathew; Utioukpan, Ashaka Fidelis; Mijinyawa, Aboki Nwunuji; Akam, Odok Endurance; Ekup, Ogholo Ogholo
African Multidisciplinary Journal of Sciences and Artificial Intelligence Vol 2 No 2 (2025): African Multidisciplinary Journal of Sciences and Artificial Intelligence
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/amjsai.v2i2.5186

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Jatropha gossypiifolia L. (Euphorbiaceae), widely known as “bellyache bush,” is a medicinal plant largely used throughout Africa and America. Several human and veterinary uses in traditional medicine are described for different parts and preparations based on this plant. The protective potentials of ethanol leaf extract of Bryophyllum pinnatum against gentamicin induced biochemical injury in Wistar albino rats were evaluated using serum biochemical parameters. Twenty-five male albino rats were divided randomly into five groups A to E. Groups C and D received 100, 200 and 300 mg/kg Jatropha gossypiifolia leaves extract respectively. Groups A and B were fed with chow (normal and positive controls) while Group E received 100 mg/kg of Vitamin C. Biochemical injury was induced in rats in groups B-E with gentamicin (i.p) at the dose of 80 mg/kg body weight on the 16th day of study. The rats were then fasted for 48 h and sacrificed by cervical dislocation. Serum was collected for biochemical analysis using standard methods and analytical biochemical kits. There was a significant increase in the serum levels of AST, ALT and ALP of the rats administered with gentamicin (Group B - positive control) compared to the Group A- normal control. However, treatment of rats with 100, 200 and 300 mg/kg body weight of ethanol leaf extract of Jatropha gossypiifolia L significantly decrease these biochemical parameters compared to Group B (p < 0.05). Also, there was a significant increase in the serum levels of conjugated bilirubin and total bilirubin in Group B compared to the normal control. Rat pre-treated with 200 and 300 mg/kg body weight of extract showed significant decrease in the conjugated and total bilirubin compared to the non-treated rats in Group B (p <0.05). Serum level of urea and creatinine significantly increased in Group B compared to normal control. Rats in groups C and D pre-treated with 200 and 300 mg/kg body weight of extract showed significant decrease in the levels of urea and creatinine compared to Group B (p <0.05). There was significant decrease in the serum levels of albumin and total protein of the rats administered with gentamicin compared to the normal control. Rats pre-treated with 200 and 300 mg/kg body weight of extract showed significant increase compared rats in non-treated Group B (p <0.05). The results obtained from this study shows that the ethanolic leaf extract of Jatropha gossypiifolia L has protective functions against gentamicin-induced hepatic and nephrotic damage in Wistar albino rats.
Co-Authors Akafa, Tensaba Andes Akam, Odok Endurance Akem, Ingwu Joseph Akem3, Ingwu Joseph Asare, Solomon Ossom Ekup, Ogholo Ogholo Hassan, Okrah George Iba, Bemhemba Kingsly, Iseko Iyoko Konka, Daniel Mijinyawa, Aboki Nwunuji Ngbede, Ocheifa Mathew Tiimob, Gideon Likida Udoh, Mary Athanasius Umaru, Isaac John Umaru, Kerenhappuch Isaac Utioukpan, Ashaka Fidelis Yahaya, Musbau Adekunle