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All Journal Journal of Multidisciplinary Science: MIKAILALSYS Asian Journal of Science, Technology, Engineering, and Art International Journal of Education, Culture, and Society International Journal of Humanities, Education, and Social Sciences
Umaru, Isaac John
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Antidiabetic Potential of Khaya Anthotheca Methanolic Leaves Extract in Streptozotocin Diabetes Induced Rats Umaru, Kerenhappuch Isaac; Tansaba, Akafa Andes; Umaru, Isaac John; Ugoeze, Egeonu Stephen; Nanmar, Chakfa; David, Bando Christopher
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 2 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i2.3191

Abstract

This research evaluated antidibetic potential of methanolic leaves extracts of Khaya anthotheca in streptozotocin induced albino rats. Khaya anthotheca a member of Meliaceae family is traditionally used for treating several ailments. Diabetes is a chronic condition that develops when the pancreas is unable to secrete sufficient amounts of insulin or when the body fails to utilise the insulin that is produced. The leaves were harvested in Sukundi road Wukari and air dried for four weeks, the leaves were pulverized into powder using manual blender and stored in an air tight container. Extraction was done with absolute methanol; the extract was filtered using mesh and the filtrate was concentrated at 68oC. two grams of the filtrate were used for the study; the remainder was used to treat the animals. Using 40 mg/kg body weight of streptozotocin, the animals were divided into 5 groups of 4 each. Following a fourteen-day course of treatment, the animals were sacrificed; the blood was drawn through heart puncture and tested for blood sugar using a glucometer. One-way analysis of variance (ANOVA) was used for statistical analysis. Result of blood sugar level showed significant reduction in all the test groups (p<0.05) except group 2 which showed no significant reduction when compared to the normal control. Conclusion: This study therefore suggests the use of Khaya anthotheca as a diabetic agent and for treatment of diabetes. Further studies are needed to discover the bioactive constituent of the plant responsible for this anti-diabetic activity as well as other pharmacological activities in clinical trials.
GC-MS Profiling and Pathogenic Effect of Khaya Anthotheca Methanolic Leaves Extract on Some Selected Fungi Umaru, Isaac John; Shadrach, Philip; Adi, Godwin Baaku; Ugoeze, Egeonu Stephen; Nanmar, Chakfa; Akafa, Andes Tensaba; Umaru, Kerenhappuch Isaac; David, Bando Christopher
Journal of Multidisciplinary Science: MIKAILALSYS Vol 2 No 2 (2024): Journal of Multidisciplinary Science: MIKAILALSYS
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/mikailalsys.v2i2.3192

Abstract

This research evaluated GC-MS profile, and pathogenic effect of methanolic leaves extracts of Khaya anthotheca on Some Selected fungi. Khaya anthotheca a member of Meliaceae family is traditionally used for treating several ailments. The leaves were harvested in Sukundi road Wukari and air dried for four weeks, the leaves were pulverized into powder using manual blender and stored in an air tight container. Extraction was done with absolute methanol; the extract was filtered using mesh and the filtrate was concentrated at 68oC. Only two grams of the filtrate were used for the GC-MS study. One-way analysis of variance (ANOVA) was used for statistical analysis. The GC-MS result revealed 50 constituents. Result of Methanolic extracts of leaves of Khaya anthotheca only showed significant activity against Aspergillus niger at dose100 µg/mL, Candida tropicalis and Fusarium oxysporium at dose 500 µg/mL. This study supports the use of Khaya anthotheca by indigenous herbalists by providing scientific proof of the plant's ability to treat pothegenic diseases. To establish the effectiveness of this plant in the management of fungal effections, more clinical trials at the clinical levels are needed.
Local Community Distribution and Participation in Biodiversity Conservation in National Parks: A Case of Gashaka Gumti National Park Safety Madaki, Kanati; Umaru, Isaac John; Umaru, Kerenhapucch Isaac
International Journal of Humanities, Education, and Social Sciences Vol 2 No 2 (2024): International Journal of Humanities, Education, and Social Sciences
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ijhess.v2i2.3084

Abstract

In this article, we investigate how the distribution of community participation impacts biodiversity conservation in national parks. This study analyzes factors that influence the distribution of community participation in biodiversity conservation. We hypothesize that employment in tourism increases the likelihood of community participation in biodiversity conservation. Additionally, we hypothesize that financial benefits derived by local people uniquely influence their likelihood of engaging in conservation activities. Furthermore, we hypothesize that infrastructure development affects household likelihood to engage in biodiversity conservation. Data were collected from households using questionnaires. Using logistic regression analysis, we find support for our hypotheses. The results suggest that local community participation in biodiversity conservation is significant. This study contributes to the growing empirical evidence on the effects of local community participation on biodiversity conservation in national parks and its implications for park managers and policymakers. Our study makes significant contributions to the existing literature and has practical implications for park management and policy formulation.
Impact of Yankari Game Reserve to Rural Development and Biodiversity Conservation in Yankari Communities Bauchi State Madaki, Kanati; Umaru, Isaac John; Umaru, Kerenhapucch Isaac
Asian Journal of Science, Technology, Engineering, and Art Vol 2 No 3 (2024): Asian Journal of Science, Technology, Engineering, and Art
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstea.v2i3.3085

Abstract

This paper assesses the development and benefits derived by rural communities in the study area surrounding a game reserve. Questionnaires were administered to residents of fourteen selected communities within the game reserve and to the staff of the park. Additionally, focus group discussions were conducted with ten residents from each of the fourteen rural communities. A total of 720 questionnaires were distributed to residents to evaluate the development and benefits received from the establishment of the game reserve, while 250 questionnaires were distributed to the park staff to determine the impact of NGO activities on the communities. Interviews were also conducted with key stakeholders, including ward-heads, village-heads, youths, and women leaders. The findings reveal that the primary developments and benefits received by the game reserve rural communities include the establishment of primary schools, clinics, health centers, construction of roads and culverts, drilling of boreholes and wells, and access to loans for income generation. However, the relationship between farmers and pastoralists is strained, particularly during the dry season when livestock damage crops due to scarce forage. It is recommended that the working relationships between the communities and the game reserve be improved to achieve the overall objectives of conservation programs in Nigeria.
Assessment of Hyperglycemic Potentials of Khaya Anthotheca Stem-Bark Extracts on Alloxan-Induced Diabetic Rats Umaru, Kerenhappuch Isaac; Nanmar, Chakfa; Umaru, Isaac John; Ugoeze, Egeonu Stephen; Tansaba, Akafa Andes; David, Bando Christopher
Asian Journal of Science, Technology, Engineering, and Art Vol 2 No 3 (2024): Asian Journal of Science, Technology, Engineering, and Art
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstea.v2i3.3183

Abstract

Introduction: Medicinal plants have been the basis of treatment of various diseases in African traditional medicine as well as other forms of treatment from diverse cultures of the world. Khaya anthotheca is a member of the family Meliaceae, a native to Africa. It is a medicinal plant widely used for several therapeutic purposes. Herein, phytochemical study, hyperglycaemic investigations was carried out on the methanol extract of Khaya anthotheca Stem-bark. Materials and Methods: However, 35 rats were distributed into seven groups to evaluate the anti-diabetic activity of K. anthotheca stem-bark methanol extract at the dosage range of 50-400 mg/kg/b.wt. The analysis was done using the software-SPSS one-way ANOVA at a significance level p<0.05. Results: The result of the anti-diabetic study reveals that extract elicited substantial (p<0.05) inhibition of hyperglycaemic. The plant Khaya anthotheca stem-bark methanol extract displayed profound (p<0.05) anti-hyperglycaemic action at the dosage of 200 mg/kg/b.wt, 300 mg/kg/b.wt. and 500 mg/kg/b.wt. against induced diabetic rats. Conclusion: This study therefore suggests the use of Khaya anthotheca as a hypoglycaemic agent and for treatment of diabetic. Further studies are needed to discover the bioactive constituent of the plant responsible for this anti-diabetic activity.
Phytochemical Profiling, and Antifungal Potentials of Stem-Bark Extracts of East African (Khaya Anthotheca) Umaru, Kerenhappuch Isaac; Ugoeze, Egeonu Stephen; Umaru, Isaac John; Nanmar, Chakfa; Tansaba, Akafa Andes; David, Bando Christopher
Asian Journal of Science, Technology, Engineering, and Art Vol 2 No 3 (2024): Asian Journal of Science, Technology, Engineering, and Art
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstea.v2i3.3185

Abstract

Fungal infection is an infectious disease that is commonly implicated as aetiologic agents that contribute to the increasing burden of morbidity and mortality in developing countries as a result misdiagnosis or improper diagnosis. This study determined the profiling and antifungal potentials of Stem-Bark Extracts of East African (Khaya Anthotheca). The methanol solvent was used for disc diffusion assay. The inhibitory concentration of the extract was performed by broth dilution method and zone of inhibition was studied by disc diffusion method at the concentration of 50, 100, 250, and 500 in DMSO. Nystatin was used as the reference control for antifungal study. The extract showed maximum inhibition potential sof zone of inhibition against most of the pathogen (Aspergillus niger, Aspergillus flavus, Candida tropicalis and Fusarium oxysporium) used at concentration 50ppm to 500ppm. The zone of inhibition for 500ppm is shown as (319.12± 0.11, 19.23 ± 0.12, 20.33±0.23* and 18.34±0.21*mm respectively). The extract showed minimum inhibition potential against Aspergillus flavus in all the concentration when compared with the control as well as to the other pathogens. Candida tropicalis and Fusarium oxysporium was found to be more sensitive to the methanol extract followed by Aspergillus flavus and Aspergillus niger lastly. The extract was found to be rich in phytochemical, with about 20 different chemical constitutes, with 12.14- Pentane, 3-ethyl-2,4-dimethyl-, 14.66-3-Hexen-2-one and 27.23-2-Nonenal, 2-pentyl-as the highest. The Present study indicates the potential usefulness of methanol extract of extract of khaya anthotheca as antifungal agent. Thus, has therefore, contributed to the pool of knowledge already available in this area of research. Considering the effects that both phytochemicals and its potentials as antifungal, it would be expedient to conduct further studies to assess its cancer potentials.
Exploring the Medicinal Properties and Health Benefits of Essential Oils in Treatment Akram, Muhammad; Abbas, Sabahat; Umaru, Isaac John
Asian Journal of Science, Technology, Engineering, and Art Vol 3 No 2 (2025): Asian Journal of Science, Technology, Engineering, and Art
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ajstea.v3i2.5282

Abstract

Essential oils are hydrophobic liquids extracted from plants by using different solvents and steam distillation procedures. They are rich in secondary metabolites, mainly terpenoids and phenylpropanoids. These metabolites provide a special aroma and strong pharmacological actions against different diseases and skin irritants. They are widely used as antifungal, antibacterial, anti-inflammatory, antidiabetic, antiviral, anti-carcinogenic, antioxidant, and anti-saying agents. The main aim of this review is to discuss the main sources or concentrations of factors affecting EOs and extensively analyze the major phytochemicals that are used for treating different diseases. In conclusion, essential oils were found to be promising agents for their anti-saying, antioxidant, and antimicrobial activities. Further studies should focus on a more detailed mechanism of their action and other possible benefits, especially to the cosmetic and pharmaceutical industries.
Gashaka Gumti National Park Tourism Development and Biodiversity Conservation Madaki, Kanati; Umaru, Isaac John; Umaru, Kerenhapucch Isaac
International Journal of Education, Culture, and Society Vol 2 No 2 (2024): International Journal of Education, Culture, and Society
Publisher : Darul Yasin Al Sys

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58578/ijecs.v2i2.3112

Abstract

Tourist activities in host environments often create land use problems, such as infrastructure development, and damage to ecosystems and habitats. These disturbances can lead to the disruption of wildlife species, affecting their normal behavior, increasing mortality, and reducing reproductive success. Despite these challenges, the direct benefits of tourism development to the local community are substantial. The study found that 76.06% of locals engaged in merchandise sales, 77.66% gained employment through park development, and 52.6% participated in tourism-related activities. Additionally, the indirect benefits of tourism development to the local community include increased security, improved wildlife conservation, enhanced infrastructure development, employment opportunities, and increased wildlife knowledge, with an average significance ranging from 26% to 45%. In conclusion, tourism development and biodiversity conservation contribute significantly to development, knowledge, employment, and awareness within the local community and the country at large.
Co-Authors Abbas, Sabahat Adi, Godwin Baaku Akafa, Andes Tensaba David, Bando Christopher Madaki, Kanati Muhammad Akram Nanmar, Chakfa Shadrach, Philip Tansaba, Akafa Andes Ugoeze, Egeonu Stephen Umaru, Kerenhappuch Isaac Umaru, Kerenhapucch Isaac