Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Media Kedokteran Hewan
Kartika Purnamasari
Unknown Affiliation
Medicine & Pharmacology Veterinary

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Probiotics and Acidifiers Enhance Intestinal Mucosal Resistance to APEC in Broilers Yulianto, Andreas Berny; Koesnoto Supranianondo; Kartika Purnamasari
Media Kedokteran Hewan Vol. 37 No. 2 (2026): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v37i2.2026.204-213

Abstract

Avian pathogenic Escherichia coli (APEC) causes disease in poultry and results in economic losses through reduced hatchability, production, and increased morbidity and mortality. This study evaluated the potential of probiotics and acidifiers to improve intestinal mucosal resistance in APEC-infected broilers. A completely randomized design was used, including six treatments with five replicates (n=30): T0(–) uninfected control, T0(+) infected control, T1 antibiotic growth promoter (AGP), T2 probiotics (5 mL/L drinking water), T3 acidifiers (5 g/kg feed), and T4 probiotics + acidifiers. The variables measured were intestinal lesions (necrosis, degeneration, and inflammation), villus morphology (height, width, and area) in the duodenum and jejunum, and feed conversion ratio (FCR). Data were analyzed using ANOVA and Duncan’s test, while lesion scores used Kruskal–Wallis and Mann–Whitney tests. All treatments differed from those of the infected control. Probiotics and acidifiers improved villus morphology and produced lower FCR than AGP, whose FCR was similar to that of the infected control. Probiotics and acidifiers show potential as alternatives to AGP in maintaining intestinal integrity in APEC-challenged broilers.
Co-Authors Andreas Berny Yulianto, Andreas Berny Koesnoto Supranianondo