Evy Diah Woelansari
Department of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya, Surabaya, Indonesia

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Diagnostic Test Fine Needle Aspiration Biopsy (FNAB) Examination on Gold Standard Histopathological Tests for Identification of Colli Lymphadenopathy Patients at RSPAL. Dr. Ramelan Surabaya Devan Andhika; Anik Handayati; Evy Diah Woelansari
International Journal of Advanced Health Science and Technology Vol. 3 No. 1 (2023): February
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i1.190

Abstract

Lymphadenopathy is a common clinical manifestation which requires rapid and accurate diagnosis. Fine Needle Aspiration Biopsy (FNAB) is used as an initial and direct diagnosis in cases of lymphadenopathy, confirmatory diagnosis of colli lymphadenopathy is carried out by histopathological examination. The purpose of this study was to determine the value of the FNAB diagnostic test for lymphadenopathy colli FNAB against the gold standard histopathology of Paraffin Blok for benign and malignant lymphadenopathy, examination data for Colli Lymphadenopathy obtained at RSPAL has never been studied before. This type of research is observational descriptive by taking medical record data (SIM-RS) of patients with lymphadenopathy in the colli region who were examined for FNAB and histopathology at the Anatomical Pathology Laboratory Installation, RSPAL dr. Ramelan Surabaya for the period January 2019 – March 2022. The sample used was selected using the total sampling method, obtained as many as 66 samples that met the inclusion criteria. The results of the FNAB examination were then matched against the histopathological gold standard examination data. Furthermore, the data was processed by 2x2 crosstabulation and diagnostic tests were carried out to determine the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. The results showed that the accuracy of the FNAB diagnostic test was 86.56%, sensitivity 80.48%, specificity 96.15%, positive predictive value 97.05%, negative predictive value 75.75%. In general, it can be stated that the FNAB examination can be a screening diagnostic tool that is easy, fast, relatively affordable and applicable in helping to establish the diagnosis of colli lymphadenopathy.
Expression of Immunoglobulin G / Immunoglobulin M Typhoid On Neutrophil-Lymphocyte Ratio In Patients At Haji Hospital, Surabaya Nur Zerlinda; Evy Diah Woelansari; Anita Dwi Anggraini
International Journal of Advanced Health Science and Technology Vol. 3 No. 4 (2023): August
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i4.289

Abstract

Typhoid fever is one of the major bacterial infections worldwide caused by the bacterium Salmonella enterica serovars typhi in humans. The examination used is the rapid Typhoid test. This rapid typhoid test is used to detect antibodies to Salmonella typhi. The purpose of the study was to determine the results of the Neutrophil - Lymphocyte Ratio with various criteria results from the Immunoglobulin G / Immunoglobulin M Test in typhoid fever patients. This type of study is descriptive observational with selective sampling taken. The samples in this study were 28 samples conducted in April 2023 on typhoid fever patients at the Hajj Hospital in East Java Province. This study used the Rapid Typhoid Test Immunochromatography method with positive Widal criteria and supporting examination using Neutrophil–Lymphocyte Ratio (NLR) with Hematology Analyzer tool Fluorescent Flow Cytometry method. Typhoid and NLR rapid test results are processed descriptively in tables and based on percentages. The results obtained from the rapid test were positive IgM of 29%, positive IgG of 11%, positive IgG and IgM of 3%, and negative IgG and IgM of 57%. The average NLR was 4,43% with a median of 2,85. IgG / IgM examination of NLR showed no significant association in typhoid fever patients. It is hoped that this research will be further developed using Salmonella culture examination.
Correlation Between HIV Rapid Test and HIV Viral Load in HIV Patients at Haji Hospital in Surabaya Resty Cahya Pertiwi; Evy Diah Woelansari; Ayu Puspitasari
International Journal of Advanced Health Science and Technology Vol. 3 No. 4 (2023): August
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v3i4.290

Abstract

HIV (Human Immunodeficiency Virus) is a virus that causes decreased immunity. Examinations that can be done for HIV testing include a rapid HIV test and HIV viral load. The rapid HIV test is a test that is used to find out the antibodies in the sample, while the viral load test is to find out the amount of HIV. The purpose of this study was to compare HIV using a rapid test with HIV viral load in people with HIV. This type of research is observational with a cross-sectional approach. The sample in this study were 30 samples from HIV sufferers who carried out an HIV viral load examination using the Molecular Rapid Test (TCM) method at the RSUD Haji Provinsi Jawa Timur, then a rapid HIV test was carried out using the immunochromatography method. The results of the HIV rapid test and HIV viral load were processed in the form of a bar chart and tested with the McNemar statistical test. The results of the McNemar test can be concluded that there is a significant difference between the results of the HIV viral load examination of HIV viral load by the Molecular Rapid Test (TCM) method is superior to the HIV rapid test. However, rapid tests can be used in diagnosing HIV infection.
Association Between Soil Transmitted Helminth Infections, Hemoglobin Levels, and Eosinophil Counts in Elementary School Children Shella Nur Laily; Retno Sasongkowati; Evy Diah Woelansari; Museyaroh
International Journal of Advanced Health Science and Technology Vol. 5 No. 6 (2025): December
Publisher : Forum Ilmiah Teknologi dan Ilmu Kesehatan (FORITIKES)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/ijahst.v5i6.499

Abstract

Soil-Transmitted Helminths (STH) remain a major public health concern among school-aged children, particularly in regions with limited sanitation and inadequate hygiene practices, where chronic parasitic exposure may impair hematological health. This study investigates the extent to which STH infection is associated with reduced hemoglobin levels and elevated eosinophil counts in elementary school children, focusing on the potential hematological and immunological consequences of infection. A cross-sectional analytical design was applied to 44 participants selected by consecutive sampling. Fecal samples were examined using the 33% zinc sulfate (ZnSO₄) flotation method to detect helminth eggs or larvae, while venous blood samples from infected participants were analyzed with an automated hematology analyzer to obtain hemoglobin concentration and eosinophil percentages. Normality testing was conducted using the Shapiro–Wilk test, and associations between variables were assessed using Spearman’s rho correlation. The findings indicate that 10 of the 44 children (22.7%) were positive for STH infection. Among these infected subjects, 70% exhibited hemoglobin levels below the normal threshold, while 60% showed eosinophil counts exceeding the reference range. Statistical analysis demonstrated a significant negative correlation between STH infection and hemoglobin levels (p = 0.040), and a significant positive correlation between STH infection and eosinophil counts (p = 0.037). These results indicate that STH infections contribute to anemia and eosinophilia, suggesting measurable disruption of hematological function. The study concludes that implementing routine deworming, blood screening, and hygiene-centered health education within school-based programs is essential to reduce STH prevalence and safeguard children’s physiological well-being and cognitive development in endemic areas.