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All Journal The New Ropanasuri Journal of Surgery
Risyaldi, Muftah
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology

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Transplantation in Pediatrics Liver Failure Associated with Acute Hepatitis of Unknown Etiology Putra, Afid B; Putranto, Agi S; Risyaldi, Muftah; Nurachman, Luthfian A
The New Ropanasuri Journal of Surgery Vol. 7, No. 2
Publisher : UI Scholars Hub

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Introduction. On 5th April 2022, some cases of severe acute hepatitis of unknown etiology in children were reported in the United Kingdom. Since then, the number has increased rapidly, with 650 probable cases identified worldwide. This review focuses on available information about managing acute liver failure (ALF) in pediatrics with acute hepatitis of unknown etiology through the perspective of hepatobiliary surgery. Method. A literature review proceeded on some databases, namely PubMed and Google Scholar. Epidemiological data and technical policy were obtained from World Health Organization and some government institutions. Results. Severe acute hepatitis can progressively develop into acute liver failure, thus requiring a liver transplantation procedure immediately. There are about 30 patients have received a liver transplant. Fourteen patients reported had died. Liver transplantation is necessary to treat acute liver failure in children with acute hepatitis of unknown etiology. The need for a liver transplant can be avoided if ALF is prevented. Conclusion. The decision to perform or not to perform a liver transplant procedure may consider indications, contraindications, possible outcomes, patient status, availability of donors, and access to transplant centers' facilities and resources.
Impact of Advanced Trauma Life Support Training for Improving Mortality Outcome: A Systematic Review and Meta-analysis Putra, Afid B; Nurachman, Luthfian A; Suryawiditya, Bagus A; Risyaldi, Muftah; Sihardo, Lam
The New Ropanasuri Journal of Surgery Vol. 8, No. 2
Publisher : UI Scholars Hub

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Introduction. The Global Burden of Disease Study has identified injuries as one of the top ten causes of death and disability worldwide. Injury is predicted to rise in the rankings by the year 2030. This study aimed to quantify the effectiveness of an Advanced Trauma Life Support (ATLS) training in improving mortality outcome after trauma injury. Method. This is a systematic review (of experimental and observational studies) and meta-analysis, reporting mortality outcome from trauma injury between ATLS-trained/certified physicians vs non-ATLS-certified. We performed literature searching through 3 electronic databases, including Cochrane (CENTRAL), MEDLINE (PubMed), and Scopus. Results. There are summarized results from 7 selected articles. The total patients included in this analysis were 11,595 patients in post-ATLS group and 21,603 patients in pre-ATLS group. There was high heterogeneity among studies (I2 = 95%) and therefore random effect model was used for analysis. Pooled analysis showed that ATLS had no significant effect in reducing the risk of mortality (OR: 0.68; 95% CI 0.39 – 1.20; p = 0.18). Although ATLS is not significantly associated with improved mortality outcomes, this meta-analysis has shown a tendency that health facilities and health workers implementing ATLS experienced lower mortality. Conclusion. ATLS is not the only aspect that contributes to patients’ survival. There are also roles in pre-emergency settings, resource availability, and experience. However, we believe that implementing the ATLS protocol in healthcare facilities will be the leading factor in improving trauma patients' management.
Co-Authors Nurachman, Luthfian A Putra, Afid B Putranto, Agi S Sihardo, Lam Suryawiditya, Bagus A