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All Journal Journal of Food and Pharmaceutical Science Journal of Food and Pharmaceutical Sciences Jurnal Sains Biomedis
Febrial Hikmah
Institut Pertanian Bogor
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience

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Rasionalitas Masyarakat dalam Swamedikasi Vitamin C selama Pandemi Covid-19 Febrial Hikmah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8502

Abstract

Background: Self-medication, both with herbs and chemical supplements, is people’s choice in dealing with the COVID-19 pandemic. Vitamin C is the most widely consumed supplement by the public on a self-medicated basis during the pandemic. Consumption of vitamin C as daily consumption must be an important concern of the community so that it becomes beneficial for the body. The aim of the study: This research was conducted to rationality of society in self-medication of vitamin C during the COVID-19 pandemic. Research method: This research is a descriptive study using a cross-sectional design. This research was conducted using a community self-medication rationality questionnaire for vitamin C, including the right indication, the right storage, the right dose, the right way of giving, the right time of administration and being aware of side effects. Result: Based on the 289 respondents in this study, it was illustrated that 90.3% of the respondents consumed vitamin C to increase their immune system and 67.1% of the respondents consumed vitamin C not only when they were sick. 76.1% of respondents knew the dose before consuming vitamin C, 86.5% of respondents consumed vitamin C <1000 mg/day, and 50.2% of respondents consumed vitamin C ≥1000 mg/week. As many as 88.2% of respondents consumed vitamin C after eating and 85.1% of respondents read the rules of consumption. As many as 68.9% of respondents read the side effects on the packaging, 85.8% of respondents did not experience side effects after consuming vitamin C, and 91.3% of respondents did not experience gastric irritation after consuming vitamin C. As many as 87.2% of respondents stored vitamin C at room temperature and 93.8% of respondents stored in a closed container. Conclusions: Public rationality in self-medication with vitamin C during the COVID-19 pandemic is a good category (82%).
Prediction of the Potential Active Compounds in Cucumber (Cucumis sativus L) against Hypertension using Pharmacological Network (Cytoscape) Camelia Maktur; Febrial Hikmah
Journal of Food and Pharmaceutical Sciences Vol 14, No 3 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.26201

Abstract

Hypertension is the leading cause of heart disease, kidney failure and stroke in Indonesia. Antihypertensive drugs have proven effective in managing blood pressure levels. However, long-term use of these medications may lead to side effects, reduce patient compliance and increased healthcare costs. Various studies have reported the cucumber (Cucumis sativus L) effect in controlling blood pressure. The purpose of this study is to investigate the molecular basis of these effects and identify the specific pathways involved. This research is a systematic review in silico network pharmacology analysis to forecast the antihypertensive potential of cucumber derived active compounds. By employing computational methods to explore plant-based therapeutic effects, the study identified bioactive components and their targets through the ChEMBL database, followed by protein validation using the Open Targets Platform. The findings contribute to the growing evidence that cucumber plants may play a role in hypertension management through multi-target mechanism.
Prediction of the Potential Active Compounds in Cucumber (Cucumis sativus L) against Hypertension using Pharmacological Network (Cytoscape) Camelia Maktur; Febrial Hikmah
Journal of Food and Pharmaceutical Sciences Vol 14, No 3 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.26201

Abstract

Hypertension is the leading cause of heart disease, kidney failure and stroke in Indonesia. Antihypertensive drugs have proven effective in managing blood pressure levels. However, long-term use of these medications may lead to side effects, reduce patient compliance and increased healthcare costs. Various studies have reported the cucumber (Cucumis sativus L) effect in controlling blood pressure. The purpose of this study is to investigate the molecular basis of these effects and identify the specific pathways involved. This research is a systematic review in silico network pharmacology analysis to forecast the antihypertensive potential of cucumber derived active compounds. By employing computational methods to explore plant-based therapeutic effects, the study identified bioactive components and their targets through the ChEMBL database, followed by protein validation using the Open Targets Platform. The findings contribute to the growing evidence that cucumber plants may play a role in hypertension management through multi-target mechanism.
Co-Authors Camelia Maktur