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Ilham Fathurrahman
Universitas Muhammadiyah Metro

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Potensi Repellent Ekstrak Kulit Jeruk Lemon (Citrus limon Linn.) terhadap Nyamuk Aedes sp. Suharno Zen; Nadya Syarifatul Fajriyah; Ilham Fathurrahman; Miftahuz Zakiyah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8849

Abstract

Jeruk lemon (Citrus limon Linn.) merupakan tanaman dengan jenis kulit yang memiliki kandungan senyawa fitokimia yaitu flavonoid, terpenoid, tanin dan limonen yang dapat dimanfaatkan sebagai insektisida nabati. Kandungan senyawa kimia tersebut memiliki kemampuan untuk mortalitas nyamuk, dan berperan sebagai racun pernapasan serta racun perut bagi nyamuk tersebut. Tujuan penelitian ini yaitu untuk mengetahui pengaruh dari ekstrak kulit jeruk lemon (Citrus limon Linn.) terhadap mortalitas nyamuk Aedes sp., serta mengetahui potensinya sebagai repellent. Jenis penelitian yang digunakan dalam penelitian ini adalah eksperimen dengan menggunakan rancangan penelitian berupa Rancangan Acak Lengkap (RAL) yang dilakukan dengan menggunakan 3 perlakuan variasi dosis ekstrak kulit jeruk lemon (Citrus limon Linn.) yaitu 25%, 27,5%, dan 30% serta kontrol (+) dan (-). Pengumpulan data dilakukan dengan melihat dan mencatat mortalitas/kematian dari nyamuk Aedes sp. setelah diberikan perlakuan dan mengamati nyamuk yang hinggap pada tubuh mencit dan menghitung jumlah nyamuk yang hinggap menggunakan rumus Daya Proteksi. Data diuji statistik menggunakan Anava Satu Jalur dan dilanjutkan dengan uji BNT (Beda Nyata Terkecil). Hasil penelitian diperoleh nilai Fhitung˃Ftabel yaitu 0,484 pada taraf α=0,05 sehingga H0 ditolak dan H1 diterima. Artinya terdapat pengaruh yang signifikan dari masing-masing perlakuan. Dosis terbaik yang efektif yaitu dosis 30% dengan jumlah nyamuk mati sebanyak 50 ekor. Daya proteksi tertinggi pada konsentrasi 30% sebesar 97,3%, sedangkan daya proteksi terendah pada konsentrasi 25% sebesar 77,1%.
Potensi Air Liur Nyamuk sebagai Biomarker Diagnosis Infeksi Dengue Suharno Zen; Nadya Syarifatul Fajriyah; Ilham Fathurrahman; Miftahuz Zakiyah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8941

Abstract

Dengue Hemorrhagic Fever (DHF) is a disease caused by the dengue virus and transmitted through the bite of the Aedes aegypti mosquito. Early diagnosis is essential to reduce the severity and mortality rate of this infection. Recent studies have shown that mosquito saliva contains specific biomarkers that can be used to detect dengue infection non-invasively. This study uses a systematic literature review method, namely tracing and analyzing various scientific publications relevant to the topic of non-invasive diagnostics for dengue. The results of the study can be concluded that: that mosquito saliva has great potential as a source of biomarkers for non-invasive dengue diagnosis. This method can be a more effective and easily accessible solution, especially in dengue endemic areas. However, to increase its effectiveness, further research is needed in the aspects of developing biomarker-based diagnostic kits, validation in various epidemiological environments, integration of this method in the global health system and regulation of policy makers
Kajian Senyawa Aktif Tanaman Obat sebagai Agen Antihipertensi pada Kehamilan Nadya Syarifatul Fajriyah; Suharno Zen; Ilham Fathurrahman; Miftahuz Zakiyah
Jurnal Sains Biomedis Vol. 1 No. 1 (2025): Jurnal Sains Biomedis
Publisher : Prodi Sains Biomedis Fakultas Ilmu Kesehatan Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/biomedis.v1i1.8949

Abstract

Hypertension during pregnancy is a major complication that poses significant risks to both maternal and fetal health. While pharmacological treatments are commonly used, their application is often limited due to potential adverse effects on fetal development, thereby necessitating safer alternative therapies, such as the use of medicinal plants. This study aims to examine the active compounds found in medicinal plants with antihypertensive potential and to evaluate their mechanisms of action within the context of pregnancy. A descriptive qualitative literature review was conducted by analyzing scientific articles published between 2010 and 2025 through databases such as PubMed, ScienceDirect, and Google Scholar. The review identified several plants, including Moringa oleifera, Zingiber officinale, Annona muricata, and Cymbopogon citratus, which contain bioactive compounds such as flavonoids, gingerol, acetogenins, and citral. These compounds contribute to blood pressure reduction through mechanisms such as vasodilation, antioxidant activity, diuretic effects, and inhibition of the angiotensin-converting enzyme (ACE). The findings suggest that these active compounds from medicinal plants have promising potential as safe antihypertensive agents during pregnancy; however, further large-scale clinical trials are necessary to confirm their long-term safety and efficacy
Co-Authors Miftahuz Zakiyah Nadya Syarifatul Fajriyah Nadya Syarifatul Fajriyah Suharno Zen Suharno Zen