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All Journal Journal of Pharmaceutical and Sciences. Jurnal Medisains Kesehatan
Boy Andre
Universitas Sumatera Barat
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Hubungan Pengetahuan Dan Motivasi Pasien Hipertensi Terhadap Kepatuhan Berobat Di Puskesmas Limau Purut Padang Pariaman Boy Andre; Yulia Fitriani; Vilma Humaira
Jurnal Medisains Kesehatan Vol. 7 No. 1 (2026): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v7i1.569

Abstract

Hypertension is a condition characterized by persistently elevated blood pressure with systolic pressure ≥140 mmHg or diastolic pressure ≥90 mmHg (WHO). Patient adherence to antihypertensive therapy is essential for controlling blood pressure and preventing complications, with knowledge and motivation playing key roles in treatment compliance. This study aimed to determine the relationship between knowledge and motivation of hypertensive patients and their medication adherence at Limau Purut Public Health Center, Padang Pariaman Regency, in 2024. This quantitative correlational study used a total sampling technique involving 84 respondents, and data were collected through guided questionnaires. The results showed that 38.1% of respondents had good knowledge and 48.8% had good motivation, while 61.9% had poor knowledge and 51.2% had low motivation. The percentage of patients adhering to treatment was 47.6%. Statistical analysis revealed a significant relationship between knowledge and medication adherence (p = 0.002; p < 0.05) and between motivation and adherence (p = 0.000; p < 0.05). These findings indicate that higher knowledge and motivation levels are associated with better adherence to hypertension therapy. Health workers are encouraged to provide educational materials, such as leaflets, to improve patients’ knowledge, motivation, and overall health outcomes.
Pengaruh suhu dan waktu infusa terhadap kandungan total flavonoid dan total fenolik pada infusa daun benalu (Scurrula feruginea) (Jack) Danser Puji Puji; Fatridha Yansen; Azuxetullatif Azuxetullatif; Boy Andre
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 3 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i3.1718

Abstract

Scurrula ferruginea (Jack) Danser has long been utilized in Indonesian traditional herbal medicine owing to its diverse bioactive constituents; however, the influence of preparation conditions on its phytochemical profile remains insufficiently characterized. This study investigated the effects of infusion temperature (60°C, 70°C, and 80°C) and steeping duration (15, 20, and 30 minutes) on the total flavonoid content (TFC) and total phenolic content (TPC) of S. ferruginea leaf infusions, employing a 3×3 Completely Randomized Factorial Design with two replicates. Spectrophotometry UV-Vis was performed to quantify TFC and TPC. Two-Way ANOVA depicted that infusion temperature exerted a highly significant effect on TFC (p< 0.001), whereas infusion duration did not significantly influence either variable. A statistically significant temperature and duration interaction was detected for TFC (p<0.001), indicating that the temperature-dependent flavonoid extraction is contingent upon the duration applied. Post hoc Tukey HSD analysis demonstrated that infusion at 70°C yielded significantly lower TFC (1.371 mg QE/g) relative to both 60°C (1.741 mg QE/g) and 80°C (1.687 mg QE/g), with no significant difference observed between the latter two temperatures. TPC remained comparatively stable across all treatment combinations, with temperature, duration, and their interaction all failing to exert a statistically significant effect. These findings establish infusion temperature as the dominant determinant of flavonoid extractability from S. ferruginea leaves, and indicate that a minimum steeping duration of 15 minutes at 60°C or 80°C is sufficient to maximize TFC without compromising TPC. This study provides an evidence-based foundation for optimizing the aqueous preparation of S. ferruginea leaf infusion as a candidate functional herbal beverage.
Co-Authors Azuxetullatif Azuxetullatif Fatridha Yansen Puji Puji Vilma Humaira Yulia Fitriani