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All Journal Journal of Social Research Jurnal Sains dan Teknologi Sehat Rakyat: Jurnal Kesehatan Masyarakat
Munadi Munadi
Universitas Syiah Kuala
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Sport Students' Hematology Profiles as Detected By The Automatic Sysmex XP-300 at Keberkatan Olahraga Senior High School In Aceh Munadi Munadi; Desiana Desiana; Cut Murzalina
Journal of Social Research Vol. 4 No. 3 (2025): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v4i3.2462

Abstract

Physical activity has long been linked to modifications in hematologic profiles as the body's compensating response to the stress of physical training. Several earlier research studies have discovered that physical activity impacts red blood cells, leukocytes, and platelets, while the findings remain contentious. Monitoring an athlete's hematologic profile is critical for effective training management. The purpose of this study is to analyze the hematologic profile of young adults who attend sports-specialized schools. This cross-sectional study included 30 students (15 males and 15 females). Blood samples were collected using standard venipuncture methods and examined on an automatic Sysmex XP-300 analyzer. The analytical results revealed that all participants had mean or median values for each complete blood count (CBC) parameter and leukocyte differential count that were normal for the general population. Females showed greater mean/median values for all CBC indices except hemoglobin, hematocrit, erythrocytes, MCHC, and RDW. For ESR (erythrocyte sedimentation rate), all participants exhibited normal levels, with females having greater levels. The leukocyte differential count showed that the results for male and female patients were comparable. Sport students' hematologic profiles are normal for the overall community. However, it is critical to remember that physical activity alters the blood and its components, prompting the need for hematologic indices specific to athletes or sports students.
Serum C-Reactive Protein Levels in Hypertensive Patients in Aceh: An Ethnic-Based Study Desiana Desiana; Cut Murzalina; Munadi Munadi
Sehat Rakyat: Jurnal Kesehatan Masyarakat Vol. 5 No. 3 (2026): Agustus 2026
Publisher : Yayasan Pendidikan Penelitian Pengabdian Algero

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54259/sehatrakyat.v5i3.8570

Abstract

Inflammation is a key factor in the pathophysiology of hypertension. One of the inflammatory biomarkers that can be used to gauge the level of systemic inflammation in hypertensive patients is C-reactive protein (CRP). This study investigated the role of CRP among hypertensive patients in Aceh according to ethnic background. This study adopted an observational analytical design. A total of 120 participants were enrolled in the study, comprising 90 hypertensive patients from three ethnic groups (Gayo, Aneuk Jamee, and Acehnese), with 30 participants in each ethnic group, and 30 normotensive individuals who served as the control group. The Kruskal-Wallis test was used to assess intergroup variations in CRP concentrations, while the Spearman’s rho correlation was used to examine the association of CRP levels among hypertensive subjects across ethnic groups in Aceh, as well as comparisons with normotensive controls. Among participants, 54% had normal CRP levels, whereas 46% had elevated levels. Mean CRP concentrations were higher in female than in males; however, this difference did not reach statistical significance (p = 0.061). Stratification by ethnic group revealed a statistically significant variation in mean CRP levels (p = 0.001), with the highest values observed among the Aneuk Jamee group. Nevertheless, no significant correlation was identified between CRP levels and the occurrence of hypertension across ethnic groups in Aceh (p > 0.05). C-reactive protein (CRP) levels varied among Aceh's ethnic groups, but there was no discernible correlation with the prevalence of hypertension. These results imply that the regulation of inflammatory processes in people with hypertension may be influenced by non-ethnic factors.
Evaluation of Serum Nitric Oxide Levels Across Ethnic Groups and Its Association with Hypertension in Aceh Desiana Gunawan; Cut Murzalina; Munadi Munadi
INSOLOGI: Jurnal Sains dan Teknologi Vol. 5 No. 5 (2026): Oktober 2026
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v5i5.9125

Abstract

Hypertension is a global health problem, affecting an estimated 1.4 billion people worldwide. The pathophysiology of hypertension is multifactorial and involves complex mechanisms, one of which is endothelial dysfunction, marked by disruption of NO production and its bioavailability. NO is a key modulator of vasodilation that takes part in controlling vascular homeostasis. This research aims to evaluate NO serum among three ethnicities in Aceh to assess its role in hypertension pathogenesis. This observational analytic research included 120 participants, comprising 90 hypertensive patients from three ethnic groups (Gayo, Aneuk Jamee, and Acehnese), with 30 participants in each ethnic group, and 30 normotensive individuals who served as the control group. The NO serum level among their ethnicities was analysed by the Kruskal-Wallis test, while the association between NO levels across three ethnicities and the control group (not hypertensive patients) was assessed by the Spearman test. The study found that the Gayo group had the highest NO level (51.79 pg/mL), followed by Aneuk Jamee (44.27 pg/mL) and the Acehnese group (31.87 pg/mL), with significant differences (p<0.001). The correlation analysis showed a weak relation, both across the three ethnic groups and when compared to the control group (p>0.05). Serum nitric oxide (NO) levels differ significantly among ethnic groups; however, no significant association was observed between ethnic groups and the incidence of hypertension.
Co-Authors Cut Murzalina Desiana Desiana Desiana Desiana Desiana Gunawan