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Artikel Tinjauan: Perbandingan Metode KLT, KCKT, dan Spektrofotometri UV-VIS untuk Deteksi dan Kuantifikasi Paraben Pada Kosmetik Hanifah Nur Widodo; Munir Alinu Mulki; Biandra Cinta Ramadhani; Salsabila Ramadani
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1193

Abstract

Parabens are widely used preservatives in cosmetic products to inhibit microbial growth; however, excessive exposure has been associated with endocrine disruption and skin irritation. This study reviews and compares analytical methods used for the identification and quantification of parabens in cosmetic products, namely Thin Layer Chromatography (TLC), UV–Vis spectrophotometry, and High-Performance Liquid Chromatography (HPLC). Literature searching was conducted through PubMed and Google Scholar for studies published between 2015 and 2025. Ten articles met the inclusion criteria as original research utilizing one of the three analytical methods. TLC is effective for preliminary qualitative identification based on Rf values but is less suitable for quantitative analysis. UV–Vis spectrophotometry allows rapid determination of paraben levels within a λmax range of 254–258 nm and provides reliable results for relatively simple matrices. HPLC generally demonstrates the highest sensitivity, specificity, and accuracy, commonly employing C18 columns, methanol–aquadest mobile phases, retention times of 3–11 minutes, and high linearity (R² ≥ 0.999). Several studies also reported paraben levels exceeding the safety limits established by BPOM RI, highlighting the importance of chromatographic confirmation in cosmetic surveillance. Therefore, the selection of analytical methods should follow a fit-for-purpose approach based on analytical objectives, matrix complexity, and regulatory requirements to ensure product safety.
Artikel Tinjauan: Peran Telemedisin dalam Memperluas Aksesibilitas Farmasi antara Masyarakat Pedesaan dan Perkotaan Salsabila Ramadani; Mela Nursapitri; Hanifah Nur Widodo; Sudarjat Sudarjat; Indah Laily Hilmi
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1203

Abstract

Telemedicine and telepharmacy play an important role in expanding access to pharmaceutical services, particularly in rural areas that face shortages of pharmacy personnel and healthcare facilities. However, comparative syntheses focusing on the differences in telemedicine implementation between rural and urban communities in Indonesia remain limited. This literature review aims to analyze the role of telemedicine in improving pharmaceutical service accessibility and to compare its implementation between rural and urban communities. The review was conducted systematically using PubMed and Google Scholar databases with the keywords “telemedicine, rural and urban telepharmacy, and telemedicine accessibility.” From 540 identified articles, 11 articles were selected based on inclusion and exclusion criteria. The findings indicate that telemedicine facilitates medication consultations, e-prescriptions, patient education, and chronic disease monitoring through various digital platforms. Several services, such as WhatsApp, Halodoc, and other digital health applications, have supported the improvement of pharmaceutical service accessibility. A significant gap was identified between telemedicine implementation in urban and rural areas, where urban communities demonstrated more optimal implementation due to better technological infrastructure and digital literacy, while rural communities continued to face limitations related to internet connectivity, healthcare facilities, and technology adoption. This literature review concludes that telemedicine significantly contributes to improving efficiency and promoting equitable access to pharmaceutical services between rural and urban communities.