Article Per Year (5 Year)
p-Index From 2021 - 2026
0.562
P-Index
This Author published in this journals
All Journal Journal of Pharmaceutical and Sciences. Natural: Jurnal Pelaksanaan Pengabdian Bergerak Bersama Masyarakat Bioteach : Biology and Biology Education Journal
Alfi Safitri
Universitas Sari Mutiara Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Other

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Artikel Review: Uji Keamanan dan Toksisitas Obat Herbal dalam Pengembangan Jamu, OHT, dan Fitofarmaka Monica Suryani; Alfi Safitri; Eva Diansari Marbun; Ade Irma Suryani; Cut Alvida Zura
Journal of Pharmaceutical and Sciences JPS Volume 9 Nomor 1 (2026)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v9i1.1393

Abstract

Background: Safety and toxicity testing are essential stages in the development of herbal medicines to ensure therapeutic efficacy without causing adverse effects. In Indonesia, herbal products are classified into traditional herbal medicines (jamu), Standardized Herbal Medicines, and phytopharmaceuticals, each requiring different levels of scientific evidence for safety and efficacy. Objective: This study aims to review the results of safety and toxicity testing of herbal medicines in the development of jamu, Standardized Herbal Medicines, and phytopharmaceuticals in Indonesia over the last five years (2020–2025). Methods: This study employed a descriptive, qualitative literature review. Scientific articles were systematically retrieved from the Garuda, Neliti, Sinta, and Google Scholar databases using relevant keywords related to herbal medicine safety and toxicity testing. A total of twelve peer-reviewed research articles published between 2020 and 2025 met the inclusion criteria. The reviewed studies involved in vivo, in vitro, and in silico testing methods, with toxicity parameters including LD₅₀, LC₅₀, biochemical markers, and histopathological changes. Results: The findings indicate that in vivo testing is the most frequently applied method and generally demonstrates a high safety profile for most herbal preparations. Jamu products are considered safe based on empirical use and standardized raw materials. Standardized Herbal Medicines demonstrate safety through acute and subchronic toxicity evaluations. At the same time, phytopharmaceuticals exhibit the highest level of safety through comprehensive testing using combined in vivo, in vitro, and in silico approaches. Most herbal ingredients fall into the non-toxic to mildly toxic category at high doses. Conclusion: Overall, the reviewed evidence suggests that Indonesian herbal medicines, including jamu, Standardized Herbal Medicines, and phytopharmaceuticals, are generally safe when used appropriately. Strengthening multidisciplinary toxicological approaches and implementing pharmacovigilance principles are essential to ensure long-term safety and support the development of evidence-based national herbal medicines.
Edukasi Manfaat Vitamin C dan E terhadap Daya Tahan Tubuh Anak SDN 064960 Nerla Sitinjak; Khalda Biantari Anjani; Lisa Emi Susanti; Suci Sri Yenti; Mahardika Lorencia; Frentika M. Nadapdap; Eva Diansari Marbun; Monica Suryani; Alfi Safitri; Mainal Furqon
Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat. Vol. 4 No. 2 (2026): May: Natural: Jurnal Pelaksanaan Pengabdian Bergerak bersama Masyarakat
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/natural.v4i2.2091

Abstract

Primary school-age children are a vulnerable group who may experience health problems if their micronutrient needs are not adequately met. A common problem that often occurs is that these children often do not fully understand the importance of vitamins C and E, which are essential for maintaining their immune system. Lack of understanding can lead to an increased risk of infection, decreased fitness conditions, and disruptions to learning activities at school. The purpose of this student service activity is carried out as an effort to increase students' understanding and awareness of the importance of consuming vitamin C and vitamin E. The method used is health education through counseling and interactive discussions, complemented by measuring the level of knowledge using pre-test and post-test. This activity involved 33 students from SDN 064960. The results showed an increase in the level of student knowledge after education was given, which was shown by the increase in the percentage of students from 24% on the pre-test test to 67% on the post-test as well as a decrease in the category of sufficient and insufficient knowledge. The conclusion of this activity shows that health education about the benefits of vitamin C and vitamin E is effective in increasing students' knowledge and awareness, so it is important to be implemented in a sustainable manner as a promotive and preventive effort in maintaining children's immunity.
Kajian Etnomedicine Tumbuhan Obat Masyarakat Desa Kalabbirang Kecamatan Bantimurung Kabupaten Maros Sulawesi Selatan Lovely Mahabbatan Qolbi; Alfi Safitri; Rifka Alifiah; Indrianti; Adriani Dahir
Biology and Biology Education Journal Vol. 3 No. 02 (2026): Volume 03 Nomor 02 September 2026
Publisher : PT. Ininnawa Paramacitra Edukasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62330/bioteach.v3i02.940

Abstract

This study examines the local wisdom of the Kalabbirang village community regarding the use of medicinal plants that have been passed down through generations to treat various diseases, including hypertension. Through interviews and observations, it was found that the community uses 36 types of medicinal plants from 22 families such as African leaves, cherry leaves, soursop leaves, and starfruit leaves, turmeric, ginger, nutmeg and others which are believed to have effects on treating diseases such as fever, aches, lowering blood pressure, and other diseases. The results of scientific research support that extracts and decoctions of these leaves have the potential to treat a disease. These plants are processed by boiling, drinking, or applying pastes, using plant parts such as leaves, fruit, flowers, seeds, bark, roots and rhizomes, from the results of interviews the most commonly used method is boiling, and the plant part that is often used is the leaf part, the boiling method is considered practical and the leaf part is used because it is easy to obtain and does not damage the plant. Active ingredients in plant parts such as flavonoids, tannins, saponins, alkaloids and other contents have a role in healing diseases. This research emphasizes the importance of preserving traditional knowledge as a source of alternative medicine that has scientific potential and is safe to use.
Co-Authors Ade Irma Suryani Adriani Dahir Cut Alvida Zura Frentika M. Nadapdap Indrianti Khalda Biantari Anjani Lisa Emi Susanti Lovely Mahabbatan Qolbi Mahardika Lorencia Mainal Furqon Marbun, Eva Diansari Monica Suryani Nerla Sitinjak Rifka Alifiah Suci Sri Yenti