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All Journal Majalah Kedokteran International Journal of Health and Pharmaceutical (IJHP) Asian Journal of Healthcare Analytics
Achnes Pangaribuan
Department Of Internal Medicine, Faculty Of Medicine Universitas Kristen Indonesia, Jakarta, Indonesia
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Value of Tygerberg Scoring for the Diagnosis and Management of Tuberculous Pericarditis Achnes Pangaribuan; Kurniyanto; Donnie Lumban Gaol; Yunus Tanggo
Majalah Kedokteran UKI Vol. 28 No. 4 (2012): OKTOBER-DESEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mkvol34iss2pp60

Abstract

Abstract Extra pulmonary tuberculosis occurs in 20% of patients with tuberculosis. Tuberculosis pericarditis is seen in 1-8% of these patients. Tuberculosis has been reported to be the cause of acute pericarditis in 60-80% of the patients in the developing world. We reported a case of 19 years old male who presented with right chest pain, cough, breathlessness, night sweat, fever, fatigue, and weight loss. From the physical examination, jugular venous pressure was high and on auscultation, the heart sounds were muffled and associated with a pericardial rub. The chest x-ray revealed enlargement of cardiac silhouette. Transthoracic echocardiography showed pericardial effusion, and mantoux tuberculin skin test were positive. Since the pericardiocentesis is not feasible in our hospital, the tygerberg tuberculous pericarditis score was applied. Furthermore, patients were given anti-TB treatment, and showed a good response to treatment.Key words: extra pulmonary tuberculosis, tuberculous pericarditis, tygerberg score Abstrak Tuberkulosis dapat menyebabkan kelainan di luar paru. Prevalensinya berkisar sekitar 20% dan dapat menyebabkan kelainan diberbagai organ seperti perikarditis pada jantung. Tuberkulosis telah dilaporkan menjadi penyebab perikarditis akut pada 60-80% pasien di negara berkembang. Pada tulisan ini dilaporkan seorang laki-laki berusia 19 tahun dengan keluhan nyeri dada kanan disertai batuk, sesak nafas, keringat malam, lemas, dan penurunan berat badan. Pada pemeriksaan fisik ditemukan peningkatan tekanan vena jugularis, dan pada auskultasi ditemukan bising jantung sesuai dengan gesekan perikardium. Pada pemeriksaan foto polos dada ditemukan pembesaran ruang jantung. Pada ekokardiografi ditemukan efusi perikardial. Karena perikardial drainase tidak dapat dilakukan, diterapkan skor tygerberg untuk diagnosis perikarditis tuberkolosis. Selanjutnya pasien diberi pengobatan anti TB, dan menunjukkan respons yang baik terhadap pengobatan.Kata kunci: tuberkulosis ekstra pulmoner, perikarditis tuberkulosis, skor tygerberg
Primary Urogenital Tuberculous Infection with Nephrolithiasis and Urosepsis Donnie L. Gaol; Achnes Pangaribuan; Budi Setiawan; Kurniyanto; Sahala Panggabean
Majalah Kedokteran UKI Vol. 30 No. 1 (2014): JANUARI - MARET
Publisher : Fakultas Kedokteran Universitas Kristen Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33541/mkvol34iss2pp60

Abstract

Abstract Tuberculosis (TB) is a multiorgan disease with varied clinical presentations. Extrapulmonal tuberculosis is found in 15-20% immunocompetent patients. Urogenital tuberculosis is the second most common form of extrapulmonary TB in countries with high incindence of TB. We present a case of a 42-year-old female who developed acute kidney injury due to urinary tract infection but later we found tuberculosis lession in her urinary bladder. Patient already treated with anti tuberculosis drugs regiment, but we could not evaluate the treatment response, because patient died due to her condition related with urosepsis. Tuberculosis urogenital is a rare condition and classical clinical symptoms of urinary tract infection may delayed the diagnosis.Key word : urogenital tuberculosis, acute kidney injury Abstrak Tuberkulosis (TB) adalah penyakit multiorgan dengan gambaran klinis bervariasi. Tuberkulosis ekstra paru terjadi pada 15–20% pasien yang imunokompeten. Tuberkulosis urogenital adalah bentuk terbanyak kedua tuberkulosis esktraparu terutama di daerah dengan epidemiologi tinggi. Pada tulisan ini dilaporkan kasus seorang perempuan berumur 42 tahun yang dirawat dengan gangguan ginjal akut karena infeksi saluran kemih. Akan tetapi pada pemeriksaan selanjutnya ditemukan gambaran lesi tuberkulosis di kandung kemih. Pasien telah mendapat terapi obat anti tuberkulosis (OAT), namun responsnya tidak dapat dinilai karena pasien meninggal akibat urosepsis. Angka kejadian yang jarang dan gejala klasik infeksi saluran kemih menyebabkan keterlambatan diagnosis tuberkulosis urogenital.Kata Kunci : tuberkulosis urogenital, gangguan ginjal akut
Relationship Between Risk Factors and The Incidence of Primary and Post-Primary Tuberculosis Achnes Pangaribuan; Andriyani Risma Sanggul; Agnes Dorothy; Vidi Posdo A. Simarmata; Vanessa Mutiara Marcelina; Febtusia Puspitasari
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 2 (2026): May 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i2.606

Abstract

Tuberculosis (TB) remains a significant global health problem, with Indonesia ranking second in the world for the highest number of cases. This study aims to analyze the relationship between various risk factors and the incidence of primary and post-primary tuberculosis in the Merdeka Public Health Center working area in 2025.Based on preliminary data, there are 122 TB patients in the region diagnosed using the Molecular Rapid Test (TCM). Identified risk factors include host factors such as male gender, productive age (15–64 years), low education, and low economic status. Additionally, home environmental factors play a crucial role in increasing transmission risk, including inadequate residential density (<9m²/person), poor ventilation, lack of natural lighting, and suboptimal air humidity. Negative preventive behaviors and exposure to cigarette smoke are also significant contributors to the incidence of the disease.Mitigation efforts require comprehensive interventions. These must focus not only on medical treatment but also on improving residential environmental conditions and educating the community on healthy behaviors.
Comparison Effectiveness of Antidiabetic Activity Extracts of Bay Leaves (Syzygium polycephalum) and Moringa Seeds (Moringa oleifera L.) Trini Suryowati; Sealtiel Bombing Rombelayuk Allorante; Achnes Pangaribuan
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.463

Abstract

The present study reports a comparative evaluation of the antidiabetic potential of ethanol extracts from Syzygium polyanthum (bay leaves) and Moringa oleifera L. (moringa seeds) based on their inhibitory activity against the α-glucosidase enzyme. Diabetes mellitus, a chronic metabolic disorder characterized by hyperglycemia due to impaired insulin secretion or action, can be managed through enzyme inhibition that delays carbohydrate hydrolysis. The investigation was conducted for five weeks using an in vitro experimental method, in which both plant materials were extracted via maceration with 70% ethanol. The α-glucosidase inhibition assay was performed spectrophotometrically at 410 nm, and the half-maximal inhibitory concentration (IC₅₀) was determined to compare the inhibitory capacities of both extracts. Phytochemical profiling revealed that bay leaf extract contains flavonoids, tannins, saponins, and steroids, while moringa seed extract contains flavonoids, alkaloids, and steroids. Results showed that bay leaf extract exhibited strong α-glucosidase inhibition with an IC₅₀ value below 100 ppm, indicating a significant potential as a natural antidiabetic agent. In contrast, moringa seed extract demonstrated weaker activity with no substantial inhibition observed at the tested concentrations. Based on comparative analysis, bay leaf extract shows a higher inhibitory efficiency, suggesting its potential application in herbal antidiabetic formulations. Further studies are recommended to explore the optimal concentration range and bioactive constituents of moringa seeds.
The Effectiveness of Rosella Tea on Lipid Profile and Blood Pressure in Hypertensive Patients with Comorbidities Hertina Silaban; Angelina Cindy Wahyudi; Achnes Pangaribuan
Asian Journal of Healthcare Analytics Vol. 5 No. 1 (2026): May 2026
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ajha.v5i1.16523

Abstract

This study contributes to public health knowledge by evaluating rosella tea as a complementary therapy for hypertensive patients with comorbidities. The process involved a systematic review and meta-analysis of 10 clinical trials published from 2015 to 2025, identified through PubMed, ScienceDirect, Google Scholar, and ResearchGate. The implementation method followed PRISMA guidelines and used RevMan 5.4 to assess Mean Differences. The study schedule focused on analyzing the latest literature up to the year 2025. Results indicate that rosella tea consumption does not significantly lower blood pressure or lipid profiles. Consequently, patients should prioritize standard pharmacological treatments until further standardized research is available.
Co-Authors Agnes Dorothy Angelina Cindy Wahyudi Budi Setiawan Donnie L. Gaol Febtusia Puspitasari Gaol, Donnie Lumban Hertina Silaban Kurniyanto Kurniyanto Sahala Panggabean Sanggul Andriyani Risma Sealtiel Bombing Rombelayuk Allorante Trini Suryowati Vanessa Mutiara Marcelina Vidi Posdo A. Simarmata Yunus Tanggo