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All Journal Biology, Medicine, & Natural Product Chemistry Lux Mensana: Journal of Scientific Health
Ery Hermawati
Universitas Tanjungpura
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health

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The Effect of Dekokta Jamu Cekok on Short Term Memory of White Rats (Rattus norvegicus L.) Male Wistar Strain Nelli Jaliyanti; Puji Astuti; Hadi Kurniawan; Ery Hermawati; Alex Alex
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.519-524

Abstract

The rising prevalence of dementia in Indonesia has resulted in a decline in memory and cognitive abilities. This condition is believed to be linked to oxidative stress caused by an imbalance between free radicals and antioxidants. Jamu cekok, a traditional herbal remedy composed of rhizomes such as Kaempferia galanga, Zingiber officinale, Curcuma longa L., and Curcuma xanthorrhiza, is known for its antioxidant properties. These antioxidants have the potential to neutralize free radicals, thereby helping to prevent degenerative diseases like dementia and Alzheimer’s, which are associated with short-term memory impairment. This study aimed to evaluate the effects of jamu cekok decoction on the short-term memory of male Wistar rats (Rattus norvegicus L.). A laboratory-based experimental study with a post-test-only control group design was conducted. Male Wistar rats were divided into three treatment groups receiving jamu cekok doses of 100, 200 and 400 mg/kg BW, and a negative control group was included. Short-term memory was assessed using the Y-maze test. The highest Y-maze alternation percentage of 65.12% was observed in the treatment group receiving a dose of 400 mg/kg BW. However, statistical analysis using the Kruskal-Wallis test showed no significant difference in Y-maze alternation percentages among the groups receiving jamu cekok (p = 0.626). The findings indicate that jamu cekok decoction did not have a significant effect on the short-term memory of male Wistar rats. Further studies with larger sample sizes and alternative assessment methods are recommended to explore its potential cognitive benefits.
INCIDENCE OF DRY EYE SYNDROME AND OCULAR COMPLAINTS ASSOCIATED WITH CONTACT LENS USE AMONG PRECLINICAL MEDICAL STUDENTS OF THE 2020–2022 COHORT Fatin Salsabila; Muhammad Asroruddin; Ery Hermawati
Lux Mensana: Journal of Scientific Health Vol. 5 Issue 1 (2026)
Publisher : jfpublisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56943/jsh.v5i1.958

Abstract

Introduction: Dry eye syndrome is a condition that affects the tear film, leading to discomfort, visual disturbances, and tear film abnormalities, which can result in damage to the surface of the eye. One of the causes of dry eyes is the use of contact lenses. This study aims to determine the incidence of dry eye syndrome and eye complaints due to the use of contact lenses in pre-clinical medical students from the 2020-2022 cohort. Methods: This research is an observational analytical study with a cross-sectional approach. A total of 23 selected students were included using total sampling technique. Variables were measured using the Contact Lens Dry Eyes Questionnaire (CLDEQ-8) and Contact Lens Discomfort Index (CLDI), as well as physical examinations including the Schirmer test and Tear Break-up Time (TBUT). Bivariate analysis was performed using Spearman's rho correlation test. Results and Analysis: Seven cases (30.43%) of dry eye were identified. Spearman's rho test revealed statistically significant negative correlations between questionnaire scores and clinical measurements (rs = -0.532 to -0.819, p < 0.05). The negative correlations found indicate that dry eye complaints experienced by contact lens users do not correspond with clinical examination results. This suggests that conventional tear tests are less capable of representing the actual discomfort experienced by contact lens users. Conclusion: The incidence of dry eye and eye complaints due to contact lens use based on the results of the questionnaire and physical examination is 7 people (30.43%).
Co-Authors Alex Alex Fatin Salsabila Hadi Kurniawan Muhammad Asroruddin Nelli Jaliyanti Puji Astuti