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All Journal Sumatera Medical Journal
Refli Hasan
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, 20155, Indonesia
Immunology & microbiology Medicine & Pharmacology

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Renal Function and Left Ventricular Ejection Fraction in Diabetic Patients with Acute Heart Failure Mery Natalia Hutapea; Refli Hasan; Abdul Halim Raynaldo; Abdullah Afif Siregar; Teuku Bob Haykal; Yuke Sarastri; Tengku Winda Ardini; Andre Pasha Ketaren; Joy Wulansari Purba; Nizam Zikri Akbar; Cut Aryfa Andra
Sumatera Medical Journal Vol. 9 No. 1 (2026): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v9i1.22989

Abstract

Background: Acute heart failure (AHF) in patients with type 2 diabetes mellitus (T2DM) is frequently complicated by renal dysfunction, which may aggravate cardiac impairment. Serum creatinine may reflect this cardio–renal interaction, but its association with left ventricular ejection fraction (LVEF) in AHF patients with T2DM remains unclear. Objective: To investigate the correlation between serum creatinine and left ventricular ejection fraction (LVEF) in patients with acute heart failure (AHF) and type 2 diabetes mellitus (T2DM). Methods: A cross-sectional study of 52 hospitalized AHF patients with T2DM. Clinical data, serum creatinine, A1C, and echocardiographic LVEF (assessed by two independent consultants) were collected. Correlation and multivariable linear regression analyses were performed. Results: The patients were middle-aged and predominantly male. Mean LVEF was 33.2 ± 9.1%, and mean serum creatinine was 1.58 ± 0.31 mg/dL. Higher serum creatinine levels were strongly associated with lower LVEF. Glycemic status (A1C) and urea levels also showed negative associations with LVEF. After adjustment, serum creatinine and A1C remained independent predictors of reduced LVEF. Conclusion: In AHF patients with T2DM, higher serum creatinine and A1C levels are independently associated with reduced LVEF, underscoring the cardio-renal-metabolic interplay in this population and highlighting the need for integrated management strategies.
Early Detection Screening for Congenital Heart Disease (CHD) in the Junior High School Student Population in the Coastal Area of Batu Bara Regency, North Sumatra Ali Nafiah Nasution; Refli Hasan; Muhammad Rusda; Mustafa Mahmud Amin; Rodiah Rahmawaty Lubis; Harisa Mardiah
Sumatera Medical Journal Vol. 9 No. 3 (2026): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v9i3.24107

Abstract

Background: Congenital Heart Disease (CHD) is a leading contributor to pediatric morbidity globally. In remote coastal regions like Indonesia, the absence of routine screening often results in delayed diagnosis, leading to irreversible cardiovascular complications. Objective: This study aimed to implement a proactive CHD screening program for junior high school students in an underserved area as a vital preventive healthcare strategy. Methods: A descriptive cross-sectional study was conducted at SMP Negeri 1 Tanjung Tiram, Batu Bara Regency, North Sumatra. A total of 190 students (aged 10–15 years) underwent screening involving anamnesis, physical examination, 12-lead electrocardiography (ECG), and portable echocardiography. Data were analyzed to determine the prevalence of undetected CHD. Results: The screening identified one positive case of Atrial Septal Defect (ASD) in a previously asymptomatic student, yielding a prevalence of 0.5%. Statistical analysis showed that this finding is consistent with global epidemiological trends (p = 1.000). Despite 97.4% of participants being asymptomatic, the use of portable diagnostic tools proved essential for identifying structural anomalies. Conclusion: School-based screening utilizing portable echocardiography is a feasible strategy for early CHD detection in remote areas. Such initiatives are essential for bridging the diagnostic gap and reducing the incidence of late-onset complications.
Co-Authors Abdul Halim Raynaldo Abdullah Afif Siregar Ali Nafiah Nasution Andre Pasha Ketaren Cut Aryfa Andra Harisa Mardiah Joy Wulansari Purba Mery Natalia Hutapea Muhammad Rusda Mustafa Mahmud Amin Nizam Zikri Akbar Rodiah Rahmawaty Lubis Tengku Winda Ardini Teuku Bob Haykal Yuke Sarastri