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All Journal Medical Journal of Indonesia Jurnal Plastik Rekonstruksi
Kreshanti, Prasetyanugraheni
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Maxillary Growth Evaluation Of Patients With Unilateral Complete Cleft Lip And Palate After Two Flap Palatoplasty With Honey Oral Drops Kreshanti, Prasetyanugraheni; Handayani, Siti; Fortuna, Forry; Pancawati, Julieta; Susanto, Amila Jeni; Wangge, Grace; Indania, Alita
Jurnal Plastik Rekonstruksi Vol. 5 No. 2 (2018): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2437.533 KB) | DOI: 10.14228/jpr.v5i2.256

Abstract

Background : Honey given as oral drops significantly precipitate epithelialization of the lateral palatal defects post two-flap palatoplasty by 2.1 times. Honey is believed to reduce wound contraction, scar formation, and would contribute as an important factor that will result in a satisfactory maxillary growth. The aim of this study is to evaluate maxillary growth as the long-term effect of rapid epithelialization of the palates treated by honey oral drops. Method : This is a case control study consisting of 2 groups; comparing maxillary growth of the UCCLP patients that were and were not given honey as oral drops following their two-flap palatoplasty in 2011-2012. The cephalometric measurements were recorded and the dental cast are evaluated using GOSLON Yardstick method.Result : This study included a total of 20 patients. Goslon Yardstick type IV are the most frequent GOSLON on both groups (40%) with moderate inter-rater reliability between examiner 1-2 and 2-3 (kappa; 0.583 and 0.512) and substantial between examiner 1-3 (kappa 0.716). Forty-percent of SNA angle in the honey group were considered as normal, while only 20% normal SNA angle were found in the control group.Conclusion: Honey oral drops following two-flap palatoplasty resulted in satisfactory SNA angle. As the completion of maxillary growth occurs at the age of 20, the results of this study would only serve as a preliminary report. Other measures to support maxillary growth should also be taken into account. Further studies are warranted to discover innovations in surgical technique that may be a major contributing factor in maxillary growth. Keywords: Maxillary growth, Two Flap Palatoplasty, honey
Comparison Study of Bacterial Profile, Wound Healing, and Cost Effectiveness in Pressure Injury Patients Using Treatment Honey Dressing and Hydrogel Putri, Nandita Melati; Margareta Lumbuun, Ruth Fitri; Kreshanti, Prasetyanugraheni; Saharman, Yulia Rosa; Tunjung, Narottama
Jurnal Plastik Rekonstruksi Vol. 9 No. 1 (2022): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v9i1.334

Abstract

Background : Pressure injury is a localized soft tissue injury caused by prolonged pressure over bony prominence. Most published papers used Manuka honey as dressing, while this product is expensive. As this reason, this study will use local product honey called Nusantara honey, to prove the use of local honey has better healing process, bacterial profile, and cost effectiveness, compared to the standard dressing, hydrogel.Method : This is a one-month experimental study conducted in patients with pressure injury that referred to our division. Parameter of the bacterial profile was taken from deep-tissue specimen. The healing process was examined with Pressure Ulcer Scale for Healing (PUSH) Tool. Cost was accumulated after all the treatment. Data was analysed with t-Test or Mann Whitney (if the distribution is not normal), with statistical significance was define as p<0.05..Result : Of 26 wounds, 12 were randomized to hydrogel and 14 to honey dressing. Characteristics were determined by sex, age, body mass index, level of consciousness, mobilization status, immobilization etiology, comorbidities, grade and location of ulcer, hemoglobin, leukocytes, and albumin level. There was clinically significant wound size reduction in honey dressing according to PUSH Tool (p=0.118). The bacterial profile and reduction were similar. Honey dressing appeared to be more cost effective in terms of dressing cost (p<0.001) and lower total cost.Conclusion: The local honey dressing has better wound healing outcome, although it is not statistically significant. Its capability of decreasing pathogens is similar with hydrogel, with lower cost, particularly the dressing cost. This local honey dressing could be a good choice as wound dressing in areas where the modern dressings are not available.
Radiological and histological assessment of a novel interlocking three-dimensional miniplate for mandibular angle fractures: an animal study Kreshanti, Prasetyanugraheni; Noviana, Deni; Priosoeryanto, Bambang Pontjo; Kekalih, Aria; Rahyussalim; Supriadi, Sugeng; Hatibie, Mendy Juniaty; Sukasah, Chaula Luthfia
Medical Journal of Indonesia Vol. 33 No. 4 (2024): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247567

Abstract

BACKGROUND Open reduction and internal fixation are considered the gold standard for managing mandibular fractures, as they effectively restore anatomical structure and functionality. Three-dimensional (3D) miniplates were developed to obtain a geometrically stable structure. However, the rigid structure of 3D miniplate may cause screw holes to be located within the fracture lines or directly above important anatomical structures. Hence, we have developed customizable interlocking 3D miniplates that allow for modifications in the configuration of the horizontal miniplates and vertical cross-struts to meet specific requirements. METHODS This study included 24 goats divided into 2 groups: interlocking 3D miniplate and standard plate. Each group was further divided into subgroups sacrificed on Days 5, 28, and 56. Radiological assessments were performed to evaluate bone, muscle, peri-implant bone, and peri-implant muscle density. Histological assessments were performed using Masson's trichome (MT) for bone healing evaluation and hematoxylin and eosin (H&E) staining for biocompatibility. RESULTS Radiological assessment indicated an increase in density across all measured parameters from Day 5 to 56. Histological evaluation from MT staining showed a significantly higher fibrocartilage in the interlocking 3D miniplate group (6.109%, IQR 1.453–10.828) compared to standard plate (1.311%, IQR 0.636–2.553; p = 0.001). Furthermore, H&E staining showed significantly higher inflammatory cell counts in the standard group on Days 28 and 56 compared to the interlocking 3D miniplate group (p = 0.027). CONCLUSIONS This study concluded that the interlocking 3D miniplate showed better bone healing properties and biocompatibility than the standard plate.
Co-Authors Anindhawati, Nur Aria Kekalih Atmaja, Tessa Miranda Bambang Pontjo Priosoeryanto Bangun, Kristaninta Boaz, Grace Deni Noviana Djaprie, Shelly M Fortuna, Forry Fortuna, Fory Gianni, Livia Faranita Grace Wangge, Grace Hakim, Intan Friscilla Harsono, Anastasia Dessy Hatibie, Mendy Juniaty Indania, Alita Kiat, Muhammad Irsyad Luh Karunia Wahyuni, Luh Karunia Margareta Lumbuun, Ruth Fitri Martina, Nungki Ratna Maulina Rachmasari, Maulina Mulyadi Mulyadi Pancawati, Julieta Putri, Nandita Melati Rahyussalim Sari, Vania Aramita Siti Handayani Sudjatmiko, Gentur Sugeng Supriadi, Sugeng Sukasah, Chaula Luthfia Susanto, Amila Jeni Syamsul Rizal Tiza, Melina Tunjung, Narottama Yulia Rosa Saharman