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All Journal Termometer: Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran Indonesian Journal of Multidisciplinary Sciences
Wilda Fasim Hasibuan
Universitas Batam
Humanities Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Health Professions Law, Crime, Criminology & Criminal Justice Public Health Social Sciences

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The Relationship Between Childhood Trauma and Insecurity in Adulthood Rismaida Pariang Ariyanti Napitupulu; Maryana; Wilda Fasim Hasibuan
Indonesian Journal of Multidisciplinary Sciences (IJoMS) Vol. 5 No. 1 (2026): Indonesian Journal of Multidisciplinary Sciences (IJoMS)
Publisher : CV. Era Digital Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59066/ijoms.v5i1.2322

Abstract

This study examines the relationship between childhood trauma and insecurity in adulthood, focusing on the psychological mechanisms that underlie this association. The primary objective is to identify how early adverse experiences contribute to adult insecurity and to analyze the mediating role of attachment styles as well as the moderating effects of resilience and social support. A quantitative cross-sectional design was employed, involving 247 participants aged 18–35 years. Data were collected using standardized instruments, including the Childhood Trauma Questionnaire (CTQ), Experiences in Close Relationships Scale (ECR-R), and validated measures of resilience and perceived social support. Statistical analyses were conducted using correlation, regression, mediation, and moderation techniques. The results indicate that childhood trauma significantly predicts adult insecurity, with attachment insecurity serving as a key mediating factor. Individuals with higher trauma exposure tend to develop maladaptive attachment patterns, which in turn increase vulnerability to insecurity in adulthood. Furthermore, resilience and social support were found to significantly reduce the strength of this relationship, highlighting their protective role. These findings emphasize that the long-term impact of childhood trauma is not only direct but also operates through complex psychological pathways. The study underscores the importance of early intervention, attachment-based approaches, and strengthening protective factors to reduce insecurity in adulthood.
Comparative Effectiveness and Safety of Lemborexant Versus Benzodiazepines in Patients with Insomnia: A Systematic Review and Meta-Analysis Kartini Hasballah; Fifin Oktaviani; Heldi Candra; Wilda Fasim Hasibuan
Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran Vol. 4 No. 3 (2026): Juli : Termometer: Jurnal Ilmiah Ilmu Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/termometer.v4i3.6976

Abstract

Chronic insomnia is a common sleep disorder that erodes quality of life, cognitive performance, and day-to-day safety. Benzodiazepines remain a mainstay of pharmacological treatment, yet their safety profile is a persistent concern, especially among older adults. Lemborexant, a newer dual orexin receptor antagonist, offers a distinct mechanism and a claim of improved safety. This review set out to weigh the two agents against each other on effectiveness and safety, focusing on daytime somnolence, fall risk, and cognitive impairment. A systematic review and meta-analysis was performed in line with the PRISMA 2020 guideline. Five databases (PubMed/MEDLINE, Scopus, EMBASE, the Cochrane Library, and ScienceDirect) were searched up to April 2026. Randomised controlled trials and comparative observational studies contrasting lemborexant with benzodiazepines or placebo in adults with insomnia were eligible. Risk of bias was appraised with the Cochrane RoB 2.0 tool and the Newcastle-Ottawa Scale. From 747 records, 18 studies entered the qualitative synthesis and 12 the quantitative analysis (n = 49,907 participants). Compared with benzodiazepines, lemborexant produced less daytime somnolence (SMD = -0.34; 95% CI: -0.52 to -0.16; p < 0.001), a lower risk of falls (log OR = -0.51; 95% CI: -0.72 to -0.30; p < 0.001), and less cognitive impairment (SMD = -0.18; 95% CI: -0.34 to -0.02; p = 0.028). Between-study heterogeneity was moderate (I² = 38-51%). Lemborexant shows a more favourable safety profile than benzodiazepines for daytime somnolence, falls, and cognition, particularly in older adults. The findings support considering lemborexant as a first-line pharmacological option for chronic insomnia when non-pharmacological therapy is unavailable or inadequate.
Co-Authors Fifin Oktaviani Heldi Candra Kartini Hasballah Maryana Rismaida Pariang Ariyanti Napitupulu