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All Journal International Journal of Innovation in Mechanical Engineering and Advanced Materials Journal of Advanced Pharmaceutical Research Sciences and Sustainability Jurnal Akuntansi Bisnis dan Humaniora
Sepriandi Parningotan
Politeknik Negeri Jakarta
Automotive Engineering Energy Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology

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Life Cycle Assessment of Pharmaceutical Packaging: Strategies for Transitioning to Algae-Based Biopolymers Sepriandi Parningotan; Eleni Dimitriou
Journal of Advanced Pharmaceutical Research Sciences and Sustainability (JAPRSS) Vol. 2 No. 1 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/japrss.v1i2.3634

Abstract

Background. Pharmaceutical packaging plays a crucial role in ensuring drug safety and stability, yet it significantly contributes to environmental degradation due to the extensive use of petroleum-based plastics. Increasing regulatory pressure and global sustainability commitments have intensified the need for environmentally responsible alternatives. Life Cycle Assessment (LCA) offers a comprehensive framework for evaluating the environmental impacts of packaging materials across their entire life cycle. Algae-based biopolymers have emerged as a promising solution due to their renewable origin and biodegradability. This study aims to assess the environmental and functional feasibility of transitioning from conventional polymers to algae-based biopolymers in pharmaceutical packaging. Purpose. A mixed-methods approach was employed, integrating LCA modeling with experimental evaluation of material performance. Representative packaging systems were analyzed using standardized LCA tools to measure global warming potential, energy consumption, water use, and waste generation. Mechanical and barrier properties were tested under controlled laboratory conditions, and comparative analysis was conducted using inferential statistical techniques. Method. Results indicate that algae-based biopolymers significantly reduce carbon emissions, energy use, and waste generation, although they require higher water inputs and exhibit slightly lower mechanical strength. Functional performance remains within acceptable pharmaceutical standards, and environmental improvements are statistically significant. Results. Findings suggest that algae-based biopolymers offer a viable pathway toward sustainable pharmaceutical packaging, balancing environmental benefits with functional requirements.. Conclusion. Representative packaging systems were analyzed using standardized LCA tools to measure global warming potential, energy consumption, water use, and waste generation. Mechanical and barrier properties were tested under controlled laboratory conditions, and comparative analysis was conducted using inferential statistical techniques.
Analisis Kelelahan Kerja: Integrasi NASA-TLX dan Metrik Fisiologis dalam Evaluasi Beban Mental dan Fisik Praktikan Permesinan Nabila Yudisha; Sepriandi Parningotan; Dhiya Luqyana; Bayu Asta Tarrosa
Jurnal Akuntansi Bisnis dan Humaniora Vol. 13 No. 2 (2026): Jurnal Akuntansi Bisnis dan Humaniora
Publisher : Politeknik Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33795/jabh.v13i2.9864

Abstract

Kelelahan kerja merupakan kondisi multidimensional yang mencakup aspek fisik, mental, dan kognitif akibat beban aktivitas yang melebihi kapasitas individu. Penelitian ini bertujuan untuk menganalisis tingkat kelelahan mahasiswa praktik permesinan dengan mengombinasikan metode subjektif NASA-TLX dan metode fisiologis melalui pengukuran denyut jantung (Heart Rate) serta konsumsi oksigen. Penelitian dilakukan terhadap mahasiswa Jurusan Teknik Mesin yang mengikuti kegiatan praktik di bengkel, dengan pengumpulan data melalui kuesioner dan pengukuran denyut jantung pada tiga kondisi: sebelum, saat, dan sesudah praktik. Hasil analisis NASA-TLX menunjukkan bahwa tingkat beban kerja mental berada pada kategori tinggi dengan skor rata-rata 64, menandakan tuntutan kognitif dan fisik yang besar selama kegiatan berlangsung. Pengukuran fisiologis memperlihatkan peningkatan konsumsi energi dari 0,90 kkal/menit sebelum praktik menjadi 1,02 kkal/menit saat praktik, lalu menurun menjadi 0,94 kkal/menit setelahnya. Temuan ini menunjukkan adanya peningkatan aktivitas metabolik dan beban kerja selama praktik. Keselarasan antara hasil subjektif dan objektif menegaskan bahwa beban kerja mahasiswa cukup tinggi, sehingga diperlukan evaluasi sistem pembelajaran praktik agar keseimbangan antara tuntutan fisik dan mental dapat tercapai.
Implementing OSA-CBM Architecture for Operational Readiness Assessment of Aging Motor Grader Engines Nova Pangastuti; Muhammad Ilham Muslimin; Sepriandi Parningotan
International Journal of Innovation in Mechanical Engineering and Advanced Materials Vol. 8 No. 1 (2026)
Publisher : Universitas Mercu Buana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22441/ijimeam.v8i1.38575

Abstract

Traditional interval-based maintenance policies for diesel engines often rely on fixed overhaul schedules recommended by Original Equipment Manufacturers (OEM), which may not accurately reflect the actual health status of aging heavy equipment in harsh mining environments. Such static approaches risk either premature, costly overhauls or catastrophic, unexpected failures. This study proposes a robust methodology by integrating Interquartile Range (IQR)-based statistical control limits within the Open System Architecture for Condition-Based Maintenance (OSA-CBM) framework to evaluate the operational readiness of an aging motor grader engine. Historical oil analysis data from May 2024 to November 2025, covering an extended operational period from 13,515 to 19,755 hours, were examined to identify wear behavior and lubricant degradation. The implementation of the seven functional layers of OSA-CBM, from data acquisition to advisory generation, ensures a structured and traceable diagnostic process. The results indicate that primary wear metal parameters, specifically iron (Fe) and chromium (Cr), remained stable with Risk Index (RI) values below unity (RI < 1), signifying a steady-state wear condition despite the engine operating far beyond typical overhaul intervals. Although a significant isolated spike in aluminum (Al) was detected with a Risk Index of 3.20, the absence of correlated increases in Fe or Cr suggests episodic contamination or a transient event rather than progressive mechanical wear. Furthermore, lubricant condition indicators, including kinematic viscosity and Total Base Number (TBN), consistently complied with SAE 15W-40 specifications. These findings demonstrate that embedding unit-specific statistical boundaries within the OSA-CBM architecture provides reliable, data-driven decision support, enabling justified operational life extension and optimized maintenance strategies for aging heavy-duty engines.
Co-Authors Bayu Asta Tarrosa Dhiya Luqyana Eleni Dimitriou Muhammad Ilham Muslimin Nabila Yudisha Nova Pangastuti