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All Journal WMJ (Warmadewa Medical Journal)
I Gusti Ayu Sri Anjani
Universitas Warmadewa
Health Professions Medicine & Pharmacology

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The Association Between Treatment Failure of Bacterial Vaginosis with Metronidazole and the Incidence of the Maternal–Perinatal Composite Index Kennedy Winartan; I Gusti Ayu Sri Anjani; Anak Agung Raka Budayasa
WMJ (Warmadewa Medical Journal) Vol 11 No 1 (2026): May 2026
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.11.1.13975.17-21

Abstract

There is high incidence of Bacterial vaginosis (BV) in pregnancy and increasing rate of treatment failure with metronidazole, the drug of choise in BV in pregnancy. The occurrence of bacterial vaginosis in pregnancy results in morbidity and complications for both the mother and the fetus, especially in untreated cases or cases of treatment failure. This study aims to determine the association between treatment failure and the incidence of the maternal–perinatal composite index (preterm labour, PPROM, low birth weight ). This is a cohort  study,  conducted at Sanjiwani Hospital, Gianyar, from September 2024 to April 2025.  involving 52 pregnant less than 20 weeks  diagnosed with BV who received metronidazole therapy, divided into two groups, 26 pregnant woman with successful treatment and 26 pregnant woman  with treatment failure.The results demonstrated that pregnant women with treatment failure of bacterial vaginosis had a 5.33-fold higher risk of maternal–perinatal complications (OR 5.33; 95% CI = 1.008–28.209; p = 0.049) compared to those with successful treatment.
Co-Authors Anak Agung Raka Budayasa Kennedy Winartan