Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Community Empowerment Nursing and Health Sciences Journal (NHSJ)
I Made Dwi Mertha Adnyana
Royal Society of Tropical Medicine and Hygiene
Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Maternal nutritional intervention for preeclampsia prevention: Integrating video-based education and local fish cooking workshops Dea Anenta Veonika; Tia Wida Ekaputri Hz; Niken Irfa Nastiti; Annissa Delfira; I Made Dwi Mertha Adnyana
Community Empowerment Vol. 11 No. 2 (2026)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.15501

Abstract

Preeclampsia remains a primary driver of maternal mortality in Indonesia, highlighting the urgency of addressing maternal nutritional status as a critical, modifiable risk factor through targeted community programs. This community service aims to elevate pregnant women's literacy regarding balanced prenatal nutrition for preeclampsia prevention while mapping their baseline nutritional profiles and risk factors. The program integrated comprehensive health screenings (anthropometric and blood pressure measurements, and medical history assessments) with interactive video screenings and hands-on cooking demonstrations featuring local fish resources. Clinical screenings revealed a high prevalence of metabolic risks: 40% of participants were obese and 35% presented with anemia. A remarkably strong positive correlation was observed between BMI and MUAC (r=0.788; p<0.001). Post-intervention assessments demonstrated a substantial surge in nutritional knowledge, most notably regarding calcium requirements (131.6%) and protein needs (104.8%). Ultimately, combining visual education with experiential cooking workshops serves as an effective, highly practical strategy to improve maternal nutritional literacy and reinforce preeclampsia prevention frameworks at primary healthcare levels.
Interleukin 10 gene promoter polymorphism –819 T/C modulates IL-10 levels independently of PGE2 in multibacillary leprosy Fitriyanti; Lipinwati; Attiya Istarini; Tia Wida Ekaputri; Niken Irfa Nastiti; I Made Dwi Mertha Adnyana; Rini Pratiwi
Nursing and Health Sciences Journal (NHSJ) Vol. 6 No. 2 (2026): June 2026
Publisher : KHD-Production

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53713/nhsj.v6i2.684

Abstract

The IL-10 –819 T/C promoter polymorphism influences cytokine production in leprosy, yet its functional interplay with serum IL-10 and prostaglandin E2 (PGE2) in Indonesian populations remains undefined. This study investigated its association with multibacillary (MB) leprosy susceptibility and systemic mediator levels. In a case–control design, 35 MB patients and 35 healthy controls from Banyuasin Regency, South Sumatra, were enrolled. PCR-RFLP was used for genotyping, and ELISA was used to quantify serum IL-10 and PGE2. Genotype and allele frequencies did not differ between groups (OR = 1.121; 95% CI: 0.439–2.863; p = 0.811), indicating no susceptibility effect. Serum IL-10 was significantly elevated in patients (median 2.15 pg/mL) versus controls (1.23 pg/mL; p = 0.033). Within cases, IL-10 exhibited a C-allele dose-dependent gradient (TT: 3.82; CT: 4.96; CC: 16.20 pg/mL), though statistically underpowered (H = 0.452; p = 0.798). PGE2 showed no intergroup differences (p = 0.142), nor correlations with genotype (p = 0.915) or IL-10 (rₛ = −0.057; p = 0.639). The IL-10 –819 T/C variant does not predict MB susceptibility but, in a pathogen-context-dependent manner, functionally amplifies IL-10 production. This genetic effect operates independently of systemic PGE2 regulation, highlighting distinct immunomodulatory pathways and supporting the CC genotype as a potential biomarker of immune-suppression severity.
Co-Authors Annissa Delfira Attiya Istarini Dea Anenta Veonika Fitriyanti Lipinwati Niken Irfa Nastiti Niken Irfa Nastiti Rini Pratiwi Tia Wida Ekaputri Tia Wida Ekaputri Hz