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All Journal ARSHI Veterinary Letters Current Biomedicine
Sus Derthi Widhyari
Division of Internal Medicine, School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Canine monocytic Ehrlichiosis in Alaskan Malamute dog in GloriaVet Pet Health Solution, Bandung, Indonesia Aqila Zata Amani; Kinanti Dwi Rahma; Aryani Sismin Satyaningtijas; Ivan Satriawan; Nurul Nadelia; Sus Derthi Widhyari
Current Biomedicine Vol. 4 No. 1 (2026): January
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.4.1.24

Abstract

Background Ehrlichiosis is an infection caused by the bacterium Ehrlichia canis, which attacks monocytes. Ehrlichiosis is characterized by anemia, lethargy, lameness, pancytopenia, hemorrhage, and weight loss. Objective This study aimed to describe the clinical findings and treatment of a dog diagnosed with Ehrlichia canis infection. Case A 5-year-old female Alaskan Malamute dog named Salt was brought to the clinic of GloriaVet Pet Health Solution, Bandung, Indonesia, with lameness and weakness, accompanied by high fever and very pale mucous membranes (pallor). Examination and treatments Dog was examined using a general examination, hematology test, biochemistry test, native smear, and IDExx SNAP© 4dx test kit. The examinations showed a positive result for Ehrlichia canis infection, along with severe pancytopenia, hyperglobulinemia, and thrombocytopenia. Diagnosis heavily relied on serology and clinical manifestation, and further PCR testing was not performed. The treatment consisted of doxycycline 10 mg/kg/day for 28 days, a 0.75% ketamine drip infusion, darbepoetin alfa, and a blood transfusion. Conclusion Dog was infected with chronic ehrlichiosis with several clinical symptoms including severe anemia. Treatment with doxycycline as the treatment of choice for ehrlichiosis infection and a blood transfusion for treating severe anemia showed signs of improvement, but were ultimately ineffective due to the poor prognosis associated with chronic ehrlichiosis and severe pancytopenia.
Infeksi Babesia spesies bersamaan dengan virus corona enterik kucing dan giardiasis pada dua kucing betina Retno Wulansari; Roro Soesatyoratih; Sus Derthi Widhyari; Suryono
ARSHI Veterinary Letters Vol. 9 No. 3 (2025): ARSHI Veterinary Letters - August 2025
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.9.3.63-64

Abstract

The premunition stage of babesiosis poses a significant risk of relapse due to immune suppression. This report describes two cats that presented to a veterinary clinic with lethargy, anorexia of several days’ duration, watery eyes, and loose stools. Both cats were unvaccinated and lived in an open environment shared with their owners. Initial clinical evaluation suggested feline coronavirus (FCoV) infection and giardiasis; however, subsequent peripheral blood smears revealed intracellular parasites consistent with Babesia sp.. The initial treatment targeted viral and protozoal infections using antiprotozoal and antiviral agents for seven days, followed by a 21-day regimen of clindamycin and multivitamins to manage babesiosis. Hematological analysis and Giemsa-stained peripheral blood smears revealed anemia, thrombocytopenia, and persistent babesiosis. Clindamycin therapy effectively reduced parasitemia and alleviated clinical signs, including anemia, anorexia, and weakness, although complete clearance of Babesia sp. from the peripheral blood was not achieved at the administered dosage.
Co-Authors Aqila Zata Amani Aryani Satyaningtijas Ivan Satriawan Kinanti Dwi Rahma Nurul Nadelia Retno Wulansari Roro Soesatyoratih Suryono