Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kesehatan dan Gizi
Najwa Trisari
Unknown Affiliation
Health Professions

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
A Review: Perbandingan Stabilitas Fisik Tablet Zat Aktif Sintesis dengan Ekstrak Tumbuhan Fadil Priyangan; Yasmin Nurfitriyanti; Cantika Abelya Febrien Wijaya; Sulton Farrel Nuruddin; Najwa Trisari; Rifqi Muhammad Hajid; Ghefira Najwa Akmila
Jurnal Ilmu Kesehatan dan Gizi Vol. 4 No. 3 (2026): Juli: Jurnal Ilmu Kesehatan dan Gizi
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jig.v4i3.9319

Abstract

Tablets are one of the most widely used pharmaceutical dosage forms because they offer various advantages, such as accurate dosing, ease of use, practicality in storage and distribution, and good stability compared to other dosage forms. The physical stability of tablets is a critical factor in ensuring the quality, safety, and efficacy of medications. In the pharmaceutical industry, the active ingredients used in tablet formulations can be derived from synthetic compounds or natural sources, such as plant extracts. This study was conducted to compare the physical stability of tablets containing synthetic active ingredients and tablets containing plant extract active ingredients. This study employed a literature review method with a descriptive-comparative approach. The results showed that tablets formulated using the wet granulation method with synthetic active ingredients exhibited consistent values for hardness, friability, and disintegration time regarding physical stability. In contrast, tablets with a plant extract active ingredients showed more variable results because the characteristics of natural materials can affect the physical stability of the tablets. Therefore, tablets with synthetic active ingredients demonstrated better physical stability compared to herbal extract tablets because the properties of synthetic active substances are more homogeneous and easier to formulate using the wet granulation method.
Co-Authors Cantika Abelya Febrien Wijaya Fadil Priyangan Ghefira Najwa Akmila Rifqi Muhammad Hajid Sulton Farrel Nuruddin Yasmin Nurfitriyanti