Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Indonesian Journal of Cancer
Cindy Adityoputri
Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Exploring the Key Factors Influencing Survival in Pediatric Acute Lymphoblastic Leukemia: A Literature Review Cindy Adityoputri; Olga Rasiyanti Siregar; Rini Savitri Daulay; Rina Amelia; Bidasari Lubis; Hendri Wijaya
Indonesian Journal of Cancer Vol. 20 No. 2 (2026): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v20i2.1464

Abstract

Acute lymphoblastic leukemia (ALL) is a hematologic malignancy characterized by the uncontrolled proliferation of immature B-cell or T-cell lymphoid progenitors. This malignancy predominantly affects children, with a peak incidence between the ages of 2 and 5 years. Data from Indonesia show an incidence of leukemia of around 4 per 100,000 children, with an estimated 2,000-3,200 new cases per year. The survival rate for childhood leukemia in Indonesia is only around 20-30%, while in developed countries, it is nearly 90%. This article aims to explore deeply the factors influencing survival in pediatric ALL through a systematic literature review of records from 1981 to 2024. Our findings suggest that low-middle-income countries, age < 1 year, male gender, malnutrition, splenomegaly, hepatomegaly, severe anemia, leukocytosis, thrombocytopenia, high-risk stratification, and poor quality of life are linked to lower survival rates.
Co-Authors Bidasari Lubis Hendri Wijaya Olga Rasiyanti Siregar Rina Amelia Rini Savitri Daulay