Claim Missing Document
Check
Articles

Found 3 Documents
Search

Formulation and Evaluation of Liquid Soap Containing Ethanolic Extract of Eleutherine palmifolia (L.) Merr. Leaves Erna Prihandiwati; Nur Ainah; Muhammad Ma'ruf; Senya Puteri Amalia; Eka Kumalasari; Muhammad Aulia Irwansyah; Olivia Olivia
Journal of Food and Pharmaceutical Sciences Vol 14, No 3 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.30088

Abstract

Eleutherine palmifolia (L.) Merr is a native plant of South Kalimantan with considerable potential for health applications. Previous studies have reported that its leaves contain various bioactive compounds, including alkaloids, flavonoids, steroids, tannins, and saponins, which contribute to antibacterial and antioxidant activities. Liquid soap is one of the most practical and widely used dosage forms for antibacterial purposes. Therefore, this study aimed to formulate and evaluate the physical characteristics of liquid soap containing ethanol extract of E. palmifolia leaves and to determine the optimal formulation that meets quality standards. An experimental study was conducted using three formulations with different concentrations of Cocamide DEA (0.5%, 1%, and 1.5%). The formulations consisted of E. palmifolia leaf extract, virgin coconut oil (VCO), potassium hydroxide (KOH), Na-CMC, stearic acid, BHT, lemongrass oil, and distilled water. The prepared liquid soaps were evaluated for pH, viscosity, foam stability, storage stability, hedonic properties, antibacterial activity, and irritation potential. The results showed that Formula 2 containing 1% Cocamide DEA exhibited the most favorable overall characteristics, providing a balance between physical stability, user comfort, and respondent acceptance. Formula 3 produced the highest foam stability but caused a dry sensation on the skin. Furthermore, Formula 2 containing 1.5% E. palmifolia extract demonstrated strong inhibitory activity against Staphylococcus aureus and moderate inhibitory activity against Escherichia coli. All formulations met the required quality parameters and showed no irritation effects. In conclusion, liquid soap formulated with 1% Cocamide DEA and 1.5% E. palmifolia leaf extract was identified as the optimal formulation. The conclusion of the results of this product meets the requirements of SNI 06-4085-1996, exhibited good physical stability, was non-irritating, and showed potential as a natural antiseptic liquid soap.
Formulation and Evaluation of Liquid Soap Containing Ethanolic Extract of Eleutherine palmifolia (L.) Merr. Leaves Erna Prihandiwati; Nur Ainah; Muhammad Ma'ruf; Senya Puteri Amalia; Eka Kumalasari; Muhammad Aulia Irwansyah; Olivia Olivia
Journal of Food and Pharmaceutical Sciences Vol 14, No 3 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.30088

Abstract

Eleutherine palmifolia (L.) Merr is a native plant of South Kalimantan with considerable potential for health applications. Previous studies have reported that its leaves contain various bioactive compounds, including alkaloids, flavonoids, steroids, tannins, and saponins, which contribute to antibacterial and antioxidant activities. Liquid soap is one of the most practical and widely used dosage forms for antibacterial purposes. Therefore, this study aimed to formulate and evaluate the physical characteristics of liquid soap containing ethanol extract of E. palmifolia leaves and to determine the optimal formulation that meets quality standards. An experimental study was conducted using three formulations with different concentrations of Cocamide DEA (0.5%, 1%, and 1.5%). The formulations consisted of E. palmifolia leaf extract, virgin coconut oil (VCO), potassium hydroxide (KOH), Na-CMC, stearic acid, BHT, lemongrass oil, and distilled water. The prepared liquid soaps were evaluated for pH, viscosity, foam stability, storage stability, hedonic properties, antibacterial activity, and irritation potential. The results showed that Formula 2 containing 1% Cocamide DEA exhibited the most favorable overall characteristics, providing a balance between physical stability, user comfort, and respondent acceptance. Formula 3 produced the highest foam stability but caused a dry sensation on the skin. Furthermore, Formula 2 containing 1.5% E. palmifolia extract demonstrated strong inhibitory activity against Staphylococcus aureus and moderate inhibitory activity against Escherichia coli. All formulations met the required quality parameters and showed no irritation effects. In conclusion, liquid soap formulated with 1% Cocamide DEA and 1.5% E. palmifolia leaf extract was identified as the optimal formulation. The conclusion of the results of this product meets the requirements of SNI 06-4085-1996, exhibited good physical stability, was non-irritating, and showed potential as a natural antiseptic liquid soap.
PENGARUH EKSTRAK BATANG AKAR KUNING (Arcangelisia flava (L.) Merr.) TERHADAP AKTIVITAS SEKSUAL MENCIT JANTAN (Mus musculus) SECARA IN VIVO Farida Istiqamah; Fajar Jamaluddin Sandhori; Nur Ainah; Senya Puteri Amalia; Desy Ayu Lestari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 11 No 1 (2026): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v11i1.2799

Abstract

Disfungsi seksual merupakan masalah umum di kalangan banyak orang dewasa dan dapat diobati dengan mengonsumsi obat herbal. Salah satu tanaman yang berpotensi sebagai afrodisiak adalah Akar Kuning (Arcangelisia flava (L.) Merr.). Penelitian ini bertujuan untuk menentukan aktivitas afrodisiak ekstrak etanol 70% dari Akar Kuning (Arcangelisia flava (L.) Merr.) menggunakan uji in vivo. Penelitian ini menggunakan uji perilaku seksual mencit jantan pendekatan, menunggangi , dan kawin. Jumlah mencit percobaan adalah 25 pasang (25 mencit jantan dan 25 mencit betina) yang dibagi menjadi lima kelompok. Kelompok I (suspensi CMC-Na), kelompok II, III, dan IV masing-masing menggunakan ekstrak etanol 70% akar kuning (150 mg/kgBB, 200 mg/kgBB, dan 250 mg/kgBB), dan kelompok V (sildenafil 0,13 mg/20g BB tikus). Pengamatan dilakukan selama satu hari menggunakan kotak libidometer yang dilengkapi dengan CCTV, kipas angin, dan lampu merah. Data dianalisis menggunakan SPSS versi 25. Berdasarkan hasil, kelompok IV (250 mg/kgBB) merupakan dosis paling optimal karena menghasilkan efek afrodisiak tertinggi pada semua parameter dibandingkan dengan kelompok II (150 mg/kgBB) dan kelompok III (200 mg/kgBB). Berdasarkan hasil penelitian ini, dapat disimpulkan bahwa ekstrak etanol 70% akar kuning (Arcangelisia flava (L.) Merr.) dapat meningkatkan efek afrodisiak.