Typhoid fever is said to be an acute infectious disease of the digestive system caused by the bacteria Salmonella Typhi and is a global infectious disease. According to the World Health Organization (WHO), approximately 11–20 million cases occur each year with a mortality rate of 128,000–161,000 people. In Indonesia, the prevalence of typhoid fever reaches 1.7% with a morbidity rate of around 500 per 100,000 people, and predominantly occurs in children aged 5–14 years. In West Sumatra Province, the incidence rate reaches 1.51% and in Pariaman City it is 1.6%. Data at Aisyiyah Pariaman Hospital shows that in 2025 there were 225. The purpose of this Scientific Paper is to provide Nursing Care to Patient Mr. B, With Typhoid Fever. The method used is a case study with 1 patient, this case study was conducted in the Muzdalifah Room of Aisyiyah Pariaman Hospital on January 28 - February 3, 2026, after the assessment, a nursing diagnosis emerged, namely: Hyperthermia, Risk of Nutritional Deficit, Constipation and Risk of Bleeding. The implementation carried out includes Hyperthermia Management, Nutritional Management, Constipation Management and Prevention of Bleeding. The evaluation obtained during 5 days of nursing care for the patient is that the Risk of nutritional deficit and constipation can be resolved on the 5th day, Hyperthermia and Risk of Bleeding can be resolved in 4 days. It is recommended to patients and families to maintain personal and environmental hygiene, consume hygienic food and drinks, and comply with treatment to prevent recurrence of typhoid fever.