Endang Darmawan
Fakultas Farmasi, Universitas Ahmad Dahlan

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Profile of Pulmonary Tuberculosis Patients with dan without Diabetes at Prof. Dr. H. Aloei Saboe Regional General Hospital Gorontalo City Siti Nur Rahmatiya Abas; Sugiyarto Surono; Haafizah Dania; Lolita; Endang Darmawan
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/7aryfn34

Abstract

Background: Pulmonary tuberculosis (TB) is still a leading cause of death from infectious diseases worldwide, and diabetes mellitus (DM) exacerbates its impact by increasing the risk of infection, worsening clinical manifestations, and lowering treatment success. Objective: To compare the characteristics of pulmonary TB patients with and without DM. Methods: An observational analytic study with a retrospective design was conducted using medical records of pulmonary TB patients at Prof. Dr. H. Aloei Saboe Hospital, Gorontalo, from January to September 2024. Results: TB-DM is most frequently found in the 55–64 years age group, whereas TB without DM is most prevalent in the 45–54 years group. Female patients dominate the TB-DM group, while male patients are more common in the TB without DM group. Conclusion: that age and sex are important determinants in the distribution of TB-DM and TB without DM, emphasizing the need for integrated screening in patients aged ≥45 years and gender-sensitive interventions for TB control.
Multimorbidity and Clinical Characteristics in Physiotherapy Utilization Among Osteoarthritis Patients: An Association Rules Mining Approach Dewi Nirmala Sari; Endang Darmawan; Sugiyarto Surono; Woro Supadmi; Abdul Fadlil
Jurnal FARMASIMED (JFM) Vol 9 No 1 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v9i1.3763

Abstract

Osteoarthritis (OA) is a chronic degenerative joint disease frequently accompanied by multimorbidity, defined as the coexistence of two or more chronic conditions in an individual. Physiotherapy is recommended as a first-line conservative modality in OA management. This study aimed to identify multimorbidity patterns associated with physiotherapy utilization and to analyze sociodemographic and clinical factors associated with physiotherapy utilization among patients with OA. This retrospective cohort study was conducted using electronic medical records of patients with OA at Sultan Agung Islamic Hospital, Semarang, Indonesia, from 2020 to 2025. Total sampling was employed, resulting in 704 patients with OA who underwent physiotherapy. Descriptive analysis was performed to characterize the patients, while logistic regression was used to identify factors associated with physiotherapy utilization. Multimorbidity patterns were identified using the FP-Growth algorithm based on support, confidence, and lift values. Most patients were aged ≥60 years (494 patients), female (448 patients), diagnosed with knee OA (633 patients), and obese (429 patients). ARM identified 22 association rules, with the combination of diabetes mellitus, hyperlipidemia, and grade 2 OA showing the highest lift value (1.24). Factors associated with physiotherapy utilization included age ≥60 years (aOR 1.82), knee OA (aOR 1.48), grade 3–4 OA (aOR 1.34), and ≥2 comorbidities (aOR 1.71). In conclusion, specific multimorbidity patterns and clinical characteristics were associated with physiotherapy utilization among patients with OA, particularly older age, knee OA, higher disease severity, and multimorbidity.